A85-Feruloyl-Esterase

Family: A85-Feruloyl-Esterase

Block: X

Parent Family: Antigen85c

Comment

Feruloyl esterases play a key role in the degradation of the intricate structure of the plant cell wall by hydrolysing the ferulate ester groups involved in the cross-linking between hemicelluloses and between hemicellulose and lignin. It belongs to a supramolecular assembly termed a cellulosome. This multienzyme complex possesses in addition to its well-described cellulolytic activity an apparatus specific for xylan degradation. Feruloyl esterases, Cinnamic acid esterases hydrolyze the ferulate groups involved in the crosslinking of arabinoxylans to lignin and thus play a key role in the degradation of the plant cell wall. clotm-xyny corresponds to the feruloyl esterase module from a 5 domain xylanase Xyn10B. This family contains enzymes corresponding to a subset of the Carbohydrate Esterase family CE1 in CAZy - Carbohydrate-Active enZYmes database (CE_1) with Ser His Asp catalytic triad. Here most of the A85-Feruloyl-Esterase are bacterial enzymes but there are few fungi proteins that belong to this family and are farther related to the other fungi feruloyl esterase belonging to other families (Tannase (Aspergillus Niger FaeB) ; 6_AlphaBeta_hydrolase, Lipase_3 (Aspergillus Niger FaeA); Esterase_phb (Penicillium funiculosum FaeB Piromyces equi ESTA). Feruloyl esterases are distributed in different sub-classes type-A B C,D and E and fall respectively in the following families. Type-A in Lipase_3, Type-B in Esterase_phb (PHB depolymerase), Type-C in Tannase, Type-D in FaeC, Type-E in A85-Feruloyl-Esterase, Type-F in BD-FAE