Bacterial_lip_FamI.3
Relationship
Comment
This family corresponds to family I.3 of the classification of Arpigny and Jaeger (1999) The N-catalytic domain (residues 1-370) contains the active site residues, Ser207, Asp255, and His313 4, 5. The C-domain contains several repeats of the RTX motif and a putative secretion signal near the C-terminus. The C-domain contains two beta-roll motifs, laterally stacked together forming the so called beta-roll sandwich. The first beta-roll motif consists of residues 373-417, containing five RTX repeats and binds three Ca2+ ions. The second beta-roll motif consists of residues 493-568, containing eight RTX repeats and binds five Ca2+ ions. HemolysinCabind (PF00353). This family contains Polyurethanases (PURase)Database
Interpro : No interpro
PIRSF : No PIRSF
Pdoc : No Pdoc
Pfam : No Pfam
Prints : No Print
EC Number : No EC Number
References (7)
| Title : Enhanced enzyme thermostability of a family I.3 lipase LipSR1 by T118A mutation at the calcium-binding site - Jiang_2023_Biotechnol.Lett__ |
| Author(s) : Jiang S , Zhou Z , Han J , Fan Q , Long Z , Wang J |
| Ref : Biotechnol Lett , : , 2023 |
| Abstract : Jiang_2023_Biotechnol.Lett__ |
| ESTHER : Jiang_2023_Biotechnol.Lett__ |
| PubMedSearch : Jiang_2023_Biotechnol.Lett__ |
| PubMedID: 37439931 |
| Gene_locus related to this paper: lacac-q5fi30 |
| Title : X-ray crystallographic and MD simulation studies on the mechanism of interfacial activation of a family I.3 lipase with two lids - Angkawidjaja_2010_J.Mol.Biol_400_82 |
| Author(s) : Angkawidjaja C , Matsumura H , Koga Y , Takano K , Kanaya S |
| Ref : Journal of Molecular Biology , 400 :82 , 2010 |
| Abstract : Angkawidjaja_2010_J.Mol.Biol_400_82 |
| ESTHER : Angkawidjaja_2010_J.Mol.Biol_400_82 |
| PubMedSearch : Angkawidjaja_2010_J.Mol.Biol_400_82 |
| PubMedID: 20438738 |
| Gene_locus related to this paper: psesp-Q9RBY1 |
| Title : Importance of the Ca2+-binding sites in the N-catalytic domain of a family I.3 lipase for activity and stability - Kuwahara_2008_Protein.Eng.Des.Sel_21_737 |
| Author(s) : Kuwahara K , Angkawidjaja C , Matsumura H , Koga Y , Takano K , Kanaya S |
| Ref : Protein Engineering Des Sel , 21 :737 , 2008 |
| Abstract : Kuwahara_2008_Protein.Eng.Des.Sel_21_737 |
| ESTHER : Kuwahara_2008_Protein.Eng.Des.Sel_21_737 |
| PubMedSearch : Kuwahara_2008_Protein.Eng.Des.Sel_21_737 |
| PubMedID: 18987131 |
| Gene_locus related to this paper: psesp-Q9RBY1 |
| Title : A calcium-gated lid and a large beta-roll sandwich are revealed by the crystal structure of extracellular lipase from Serratia marcescens - Meier_2007_J.Biol.Chem_282_31477 |
| Author(s) : Meier R , Drepper T , Svensson V , Jaeger KE , Baumann U |
| Ref : Journal of Biological Chemistry , 282 :31477 , 2007 |
| Abstract : Meier_2007_J.Biol.Chem_282_31477 |
| ESTHER : Meier_2007_J.Biol.Chem_282_31477 |
| PubMedSearch : Meier_2007_J.Biol.Chem_282_31477 |
| PubMedID: 17728256 |
| Gene_locus related to this paper: serma-lipasA |
| Title : Crystal structure of a family I.3 lipase from Pseudomonas sp. MIS38 in a closed conformation - Angkawidjaja_2007_FEBS.Lett_581_5060 |
| Author(s) : Angkawidjaja C , You DJ , Matsumura H , Kuwahara K , Koga Y , Takano K , Kanaya S |
| Ref : FEBS Letters , 581 :5060 , 2007 |
| Abstract : Angkawidjaja_2007_FEBS.Lett_581_5060 |
| ESTHER : Angkawidjaja_2007_FEBS.Lett_581_5060 |
| PubMedSearch : Angkawidjaja_2007_FEBS.Lett_581_5060 |
| PubMedID: 17923123 |
| Gene_locus related to this paper: psesp-Q9RBY1 |
| Title : Lipases for biotechnology - Jaeger_2002_Curr.Opin.Biotechnol_13_390 |
| Author(s) : Jaeger KE , Eggert T |
| Ref : Curr Opin Biotechnol , 13 :390 , 2002 |
| Abstract : Jaeger_2002_Curr.Opin.Biotechnol_13_390 |
| ESTHER : Jaeger_2002_Curr.Opin.Biotechnol_13_390 |
| PubMedSearch : Jaeger_2002_Curr.Opin.Biotechnol_13_390 |
| PubMedID: 12323363 |
| Title : Bacterial lipolytic enzymes: classification and properties - Arpigny_1999_Biochem.J_343_177 |
| Author(s) : Arpigny JL , Jaeger KE |
| Ref : Biochemical Journal , 343 :177 , 1999 |
| Abstract : Arpigny_1999_Biochem.J_343_177 |
| ESTHER : Arpigny_1999_Biochem.J_343_177 |
| PubMedSearch : Arpigny_1999_Biochem.J_343_177 |
| PubMedID: 10493927 |
Structures (9)
Genes Proteins in Bacterial_lip_FamI.3 family (34)
No fragment of genes
Structures in Bacterial_lip_FamI.3 family (9)Substrates in Bacterial_lip_FamI.3 family (8)
Inhibitors in Bacterial_lip_FamI.3 family (1)