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Family Report for: MEST-like

MEST-like



Relationship
Family MEST-like
Block X
Parent Family : Epoxide-hydrolase_like

Comment
Mesoderm-specific transcript (Mest) predominantly expressed in mesoderm and its derivatives is also an imprinted gene whose expression is dependent on parental origin and is designated Peg1 (paternally expressed gene-1). Curiously orthologues seem present in vertebrates, few invertebrates (molluscs, ticks, amphioxus) but not in insects or nematodes. Absent in plants and present in a limited number of bacteria

Database
Sequences
Interpro
|
PIRSF
|
Pdoc
|
PFam
|
PF12697 (Abhydrolase_6)
Prints
|
Prosite
|
no EC number



Peptide in
|Fasta
Nucleotide in
|Fasta
Alignment with Multalin
|Text only/graphic display
Seed alignment with MAFFT
|No colour/coloured with Mview
Alignment with MAFFT
|No colour/coloured with Mview
Dendrogram
|Graphical display, obtained with the dnd file produced by Clustalw

References
11 more
    Title: Mesoderm-specific transcript is associated with fat mass expansion in response to a positive energy balance
    Nikonova L, Koza RA, Mendoza T, Chao PM, Curley JP, Kozak LP
    Ref: FASEB Journal, 22:3925, 2008 : PubMed

            

    Title: Abnormal maternal behaviour and growth retardation associated with loss of the imprinted gene Mest
    Lefebvre L, Viville S, Barton SC, Ishino F, Keverne EB, Surani MA
    Ref: Nat Genet, 20:163, 1998 : PubMed

            

    Title: Genomic structure and parent-of-origin-specific methylation of Peg1
    Lefebvre L, Viville S, Barton SC, Ishino F, Surani MA
    Ref: Hum Mol Genet, 6:1907, 1997 : PubMed

            

Other Papers


No structure scheme yet for this family

No Structure yet in this family

Genes Proteins in MEST-like family (58)

Fragments of genes in MEST-like family (2)

No Substrate

No Inhibitor



Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page
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