Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1) Hydrolyase ccsE
Cytochalasin biosynthesis protein E. Hydrolyase\; part of the gene cluster that mediates the biosynthesis of a family of the mycotoxins cytochalasins E and K. The hydrolyase ccsE may catalyze hydrolysis of epoxide bond in cytochalasin E to afford cytochalasin K
MHKLFKNAPF FDFEAIRILG TTCYGGADVA EVFEAVDQIK NNDPETWETA WRIQAERAEK LAAEALEHGD RDAALAGYLR ASNYTRASGY MYVSRAESSG EALVQDARAL PIAEKVGELF RKAIPLMKGS VHTLGIPYEE YALPGYLYLP PPWRRIPGRK IPILVNSGGA DSCQEELFYL NPAAGPGQGY AVVTFDGPGQ GIMLRKYGLE MRPDWEAVTG RVIDFLEEYA AENPHLELDL NCIAVSGASM GGYYALRAAA DQRVKACVSI DPFYDMWDFG TAHVSPIFIH AWTSGWISGG FVDNLMALLS RLSFQLRWEI SVTGTFFGLS SPSQILLHMK KYTLRSTEEE PEGFLSRVIC PVLLSGAGKS LYLDVDNHTR QCYDGLVNVA ERNKQLWIPE SEGQGSLQAK MGAFRLCNQR TYRFLDECFG IMRKSL
| Title : Chemical and Genetic Studies on the Formation of Pyrrolones During the Biosynthesis of Cytochalasans - Zhang_2021_Chemistry_10_3106 |
| Author(s) : Zhang H , Hantke V , Bruhnke P , Skellam E , Cox RJ |
| Ref : Chemistry , 10 :3106 , 2021 |
| Abstract : Zhang_2021_Chemistry_10_3106 |
| ESTHER : Zhang_2021_Chemistry_10_3106 |
| PubMedSearch : Zhang_2021_Chemistry_10_3106 |
| PubMedID: 33146923 |
| Gene_locus related to this paper: phano-phmG , aspcl-CCSE , aspfu-psoB , mago7-ORFZB , maggr-pyie |
| Title : Investigating the Function of Cryptic Cytochalasan Cytochrome P450 Monooxygenases Using Combinatorial Biosynthesis - Wang_2019_Org.Lett_21_8756 |
| Author(s) : Wang C , Becker K , Pfutze S , Kuhnert E , Stadler M , Cox RJ , Skellam E |
| Ref : Org Lett , 21 :8756 , 2019 |
| Abstract : Wang_2019_Org.Lett_21_8756 |
| ESTHER : Wang_2019_Org.Lett_21_8756 |
| PubMedSearch : Wang_2019_Org.Lett_21_8756 |
| PubMedID: 31644300 |
| Gene_locus related to this paper: phano-phmG , aspcl-CCSE , aspfu-psoB , mago7-ORFZB , maggr-pyie |
| Title : Heterologous expression of the avirulence gene ACE1 from the fungal rice pathogen Magnaporthe oryzae - Song_2015_Chem.Sci_6_4837 |
| Author(s) : Song Z , Bakeer W , Marshall JW , Yakasai AA , Khalid RM , Collemare J , Skellam E , Tharreau D , Lebrun MH , Lazarus CM , Bailey AM , Simpson TJ , Cox RJ |
| Ref : Chem Sci , 6 :4837 , 2015 |
| Abstract : Song_2015_Chem.Sci_6_4837 |
| ESTHER : Song_2015_Chem.Sci_6_4837 |
| PubMedSearch : Song_2015_Chem.Sci_6_4837 |
| PubMedID: 29142718 |
| Gene_locus related to this paper: phano-phmG , aspcl-CCSE , aspfu-psoB , mago7-ORFZB |
| Title : Identification and engineering of the cytochalasin gene cluster from Aspergillus clavatus NRRL 1 - Qiao_2011_Metab.Eng_13_723 |
| Author(s) : Qiao K , Chooi YH , Tang Y |
| Ref : Metab Eng , 13 :723 , 2011 |
| Abstract : Qiao_2011_Metab.Eng_13_723 |
| ESTHER : Qiao_2011_Metab.Eng_13_723 |
| PubMedSearch : Qiao_2011_Metab.Eng_13_723 |
| PubMedID: 21983160 |
| Gene_locus related to this paper: aspcl-CCSE |