Aspergillus usamii; Aspergillus niger; Aspergillus lacticoffeatus; Aspergillus brasiliensis AuEH2 Microsomal epoxide hyddrolase (EC 3.3.2.3)
Other strains: Aspergillus usamii E001\; Aspergillus niger (strain ATCC 1015 \/ CBS 113.46 \/ FGSC A1144 \/ LSHB Ac4 \/ NCTC 3858a \/ NRRL 328 \/ USDA 3528.7) Aspergillus lacticoffeatus CBS 101883\; Aspergillus brasiliensis CBS 101740. The sequence of Aspergillus usamii has been published and the structure of the enzyme is anounced (only 2 residues different between species
MALAYSNIPL GATVIPSPFQ VHISDEQIEE LQLLVKLSKL APPTYEGLQQ DRRYGITNEW LANAKEAWKS FDWRPAESRI NSFPQFTYDI EGLTIHFVAL FSEKKDAIPI VLLHGWPGSF LEFLPVLTSI RDKYSPETLP YHIVVPSLPG YTFSSGPPLD VNFNGEDTAR VINKVMLNLG FEDGYVAQGG DIGSKIGRIL AVDHDACKAV HLNACYMGKP SSIPDTAITE EDKRALARAQ WFATFGSGYA VEHGTRPSTI GNALSTSPVA LLSWIGEKFL DWAGETIPLE TILESVTLYW FTETFPRSIY HYRENFPPPK LRHTEDPRWY IRKPFGFSYY PMELVPTPRA WVETTGNLVF WQAHEKGGHF AALERPQDYL DDLTAFCEQV WAGRK
Title : Structure-Guided Regulation in the Enantioselectivity of an Epoxide Hydrolase to Produce Enantiomeric Monosubstituted Epoxides and Vicinal Diols via Kinetic Resolution - Hu_2022_Org.Lett__ |
Author(s) : Hu D , Hu BC , Hou XD , Zhang D , Lei YQ , Rao YJ , Wu MC |
Ref : Org Lett , : , 2022 |
Abstract : Hu_2022_Org.Lett__ |
ESTHER : Hu_2022_Org.Lett__ |
PubMedSearch : Hu_2022_Org.Lett__ |
PubMedID: 35229602 |
Gene_locus related to this paper: aspng-q1ktb5 |
Title : Structure-guided improvement in the enantioselectivity of an Aspergillus usamii epoxide hydrolase for the gram-scale kinetic resolution of ortho-trifluoromethyl styrene oxide - Wen_2021_Enzyme.Microb.Technol_146_109778 |
Author(s) : Wen Z , Hu D , Hu BC , Zhang D , Huang JF , Wu MC |
Ref : Enzyme Microb Technol , 146 :109778 , 2021 |
Abstract : Wen_2021_Enzyme.Microb.Technol_146_109778 |
ESTHER : Wen_2021_Enzyme.Microb.Technol_146_109778 |
PubMedSearch : Wen_2021_Enzyme.Microb.Technol_146_109778 |
PubMedID: 33812566 |
Gene_locus related to this paper: aspng-q1ktb5 |
Title : Nearly perfect kinetic resolution of racemic o-nitrostyrene oxide by AuEH2, a microsomal epoxide hydrolase from Aspergillus usamii, with high enantio- and regio-selectivity - Hu_2021_Int.J.Biol.Macromol_169_1 |
Author(s) : Hu D , Hu BC , Wen Z , Zhang D , Liu YY , Zang J , Wu MC |
Ref : Int J Biol Macromol , 169 :1 , 2021 |
Abstract : Hu_2021_Int.J.Biol.Macromol_169_1 |
ESTHER : Hu_2021_Int.J.Biol.Macromol_169_1 |
PubMedSearch : Hu_2021_Int.J.Biol.Macromol_169_1 |
PubMedID: 33316339 |
Gene_locus related to this paper: aspng-q1ktb5 |
Title : Near-perfect kinetic resolution of racemic p-chlorostyrene oxide by SlEH1, a novel epoxide hydrolase from Solanum lycopersicum with extremely high enantioselectivity - Hu_2020_Int.J.Biol.Macromol_147_1213 |
Author(s) : Hu BC , Hu D , Li C , Xu XF , Wen Z , Wu MC |
Ref : Int J Biol Macromol , 147 :1213 , 2020 |
Abstract : Hu_2020_Int.J.Biol.Macromol_147_1213 |
ESTHER : Hu_2020_Int.J.Biol.Macromol_147_1213 |
PubMedSearch : Hu_2020_Int.J.Biol.Macromol_147_1213 |
PubMedID: 31739010 |
Gene_locus related to this paper: aspng-q1ktb5 |
Title : Enantioconvergent hydrolysis of racemic styrene oxide at high concentration by a pair of novel epoxide hydrolases into (R)-phenyl-1,2-ethanediol - Wang_2017_Biotechnol.Lett_39_1917 |
Author(s) : Wang R , Hu D , Zong X , Li J , Ding L , Wu M |
Ref : Biotechnol Lett , 39 :1917 , 2017 |
Abstract : Wang_2017_Biotechnol.Lett_39_1917 |
ESTHER : Wang_2017_Biotechnol.Lett_39_1917 |
PubMedSearch : Wang_2017_Biotechnol.Lett_39_1917 |
PubMedID: 28875350 |
Gene_locus related to this paper: vigra-Vreh3 , aspng-q1ktb5 |
Title : Kinetic resolution of racemic styrene oxide at a high concentration by recombinant Aspergillus usamii epoxide hydrolase in an n-hexanol\/buffer biphasic system - Hu_2016_J.Biotechnol_236_152 |
Author(s) : Hu D , Wang R , Shi XL , Ye HH , Wu Q , Wu MC , Chu JJ |
Ref : J Biotechnol , 236 :152 , 2016 |
Abstract : Hu_2016_J.Biotechnol_236_152 |
ESTHER : Hu_2016_J.Biotechnol_236_152 |
PubMedSearch : Hu_2016_J.Biotechnol_236_152 |
PubMedID: 27546798 |
Gene_locus related to this paper: aspng-q1ktb5 |
Title : Expression of a novel epoxide hydrolase of Aspergillus usamii E001 in Escherichia coli and its performance in resolution of racemic styrene oxide - Hu_2015_J.Ind.Microbiol.Biotechnol_42_671 |
Author(s) : Hu D , Tang CD , Yang B , Liu JC , Yu T , Deng C , Wu MC |
Ref : J Ind Microbiol Biotechnol , 42 :671 , 2015 |
Abstract : Hu_2015_J.Ind.Microbiol.Biotechnol_42_671 |
ESTHER : Hu_2015_J.Ind.Microbiol.Biotechnol_42_671 |
PubMedSearch : Hu_2015_J.Ind.Microbiol.Biotechnol_42_671 |
PubMedID: 25733186 |
Gene_locus related to this paper: aspng-q1ktb5 |