bunfa-ACHE

Comment

Alternate Cterminus: S or T peptide (Trembl O73748)

Relationship

Family : ACHE

Block : C

Position in NCBI Life Tree : Bungarus fasciatus

Molecular evidence

No mutation

4QWW

Acetylthiocholine_WT_bunfa-ACHE Acetylthiocholine_M70Y_bunfa-ACHE Acetylthiocholine_K285D_bunfa-ACHE Acetylthiocholine_M70Y\/K285D_bunfa-ACHE Decamethonium_WT_bunfa-ACHE Decamethonium_M70Y_bunfa-ACHE Decamethonium_K285D_bunfa-ACHE Decamethonium_M70Y\/K285D_bunfa-ACHE BW284C51_WT_bunfa-ACHE BW284C51_M70Y_bunfa-ACHE BW284C51_K285D_bunfa-ACHE BW284C51_M70Y\/K285D_bunfa-ACHE Edrophonium_WT_bunfa-ACHE Edrophonium_M70Y_bunfa-ACHE Edrophonium_K285D_bunfa-ACHE Edrophonium_M70Y\/K285D_bunfa-ACHE Propidium_WT_bunfa-ACHE Propidium_M70Y_bunfa-ACHE Propidium_K285D_bunfa-ACHE Propidium_M70Y\/K285D_bunfa-ACHE Gallamine~Flaxedil_WT_bunfa-ACHE Gallamine~Flaxedil_M70Y_bunfa-ACHE Gallamine~Flaxedil_K285D_bunfa-ACHE Gallamine~Flaxedil_M70Y\/K285D_bunfa-ACHE D-tubocurarine_WT_bunfa-ACHE D-tubocurarine_M70Y_bunfa-ACHE D-tubocurarine_K285D_bunfa-ACHE D-tubocurarine_M70Y\/K285D_bunfa-ACHE WT-fasciculin2_WT_bunfa-ACHE WT-fasciculin2_M70Y_bunfa-ACHE WT-fasciculin2_K285D_bunfa-ACHE WT-fasciculin2_M70Y\/K285D_bunfa-ACHE

No disease

Acetylcholine Acetylthiocholine

No inhibitor

Database

AAC59905 U54591 BFU54591 AAC16421

Q92035

Sequence

Peptide

MPSCQPGKMP APWPWWLQLL LCIPSCVAVL PGRAGELKVS TQTGSVRGLS LPVLDGHVSA FLGIPFAEPP LGRMRFLRPE PVKPWQHVLD ATSYKPACYQ MVDTSYPGFQ GTEMWNPNRG MSEDCLYLNI WVPSPRPKDA PVLVWIYGGG FYSGAASLDV YDGRFLTYTQ NVILVSLSYR VGAFGFLGLP GSPEAPGNMG LLDQRLALQW IQNNIHPFGG NPRAVTVFGE SAGAASVGMH LLSTQSRTLF QRAILQSGGP NAPWATVTPA ESRGRAALLG KQLGCHFNND SELVSCLRSK NPQELIDEEW SVLPYKSIFR FPFVPVIDGD FFPDTPEAML SSGNFKETQV LLGVVKDEGS YFLIYGLPGF SKDNESLISR ADFLEGVRMS VPHANDIATD AVVLQYTDWQ DQDNREKNRE ALDDIVGDHN VICPVVQFAN DYAKRNSKVY AYLFDHRASN LLWPPWMGVP HGYEIEFVFG LPLNDSLNYT PQEKELSRRM MRYWANFART GNPTDPADKS GAWPTYTASQ PQYVQLNTQP LATQPSLRAQ ICAFWNHFLP KLLNATVDPP RADRRRRSAR A

References

Title : Crystal Structure of Snake Venom Acetylcholinesterase in Complex with Inhibitory Antibody Fragment Fab410 Bound at the Peripheral Site: EVIDENCE FOR OPEN AND CLOSED STATES OF A BACK DOOR CHANNEL - Bourne_2015_J.Biol.Chem_290_1522

Author(s) : Bourne Y , Renault L , Marchot P

Ref : Journal of Biological Chemistry , 290 :1522 , 2015

Abstract : Bourne_2015_J.Biol.Chem_290_1522

ESTHER : Bourne_2015_J.Biol.Chem_290_1522

PubMedSearch : Bourne_2015_J.Biol.Chem_290_1522

PubMedID: 25411244

Gene_locus related to this paper: bunfa-ACHE

Title : Cloning and expression of acetylcholinesterase from Bungarus fasciatus venom. A new type of cooh-terminal domain\; involvement of a positively charged residue in the peripheral site - Cousin_1996_J.Biol.Chem_271_15099

Author(s) : Cousin X , Bon S , Duval N , Massoulie J , Bon C

Ref : Journal of Biological Chemistry , 271 :15099 , 1996

Abstract : Cousin_1996_J.Biol.Chem_271_15099

ESTHER : Cousin_1996_J.Biol.Chem_271_15099

PubMedSearch : Cousin_1996_J.Biol.Chem_271_15099

PubMedID: 8662867

Gene_locus related to this paper: bunfa-ACHE

bunfa-ACHE

Comment

Relationship

Molecular evidence

Mutation (0)

Structure (1)

Kinetic (32)

Disease (0)

Substrate (2)

Inhibitor (0)

Database

Genbank (3)

Interpro (1)

Pfam (1)

UniProt (1)

PIRSF (1)

SUPERFAM (1)

Sequence

Peptide

References

Crystal Structure of Snake Venom Acetylcholinesterase in Complex with Inhibitory Antibody Fragment Fab410 Bound at the Peripheral Site: EVIDENCE FOR OPEN AND CLOSED STATES OF A BACK DOOR CHANNEL

Cloning and expression of acetylcholinesterase from Bungarus fasciatus venom. A new type of cooh-terminal domain\; involvement of a positively charged residue in the peripheral site