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cioin-ACHE2

Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis) Acetylcholinesterase ciad078c14 gene ci0100131198

Comment

This is the second AChE (not a cholinesterase see Frederick et al.)(the first introduced in ESTHER) It is farther related to vertebrates acche and is found only in adult cDNA library .It is not a contaminant as it is found in the genome ci0100131198. (Warning ci0100131198 is not properly conceptually spliced there is extra N-term unrelated sequence and some sequence is missing in C-term). The cioin-ACHE1 ( pointed to us by Leo Pezzementi) is found more often and is be the real AChE || F7A0M2 F6Y1Y9 partial

Relationship

Family : Cholinesterase-like

Block : C

Position in NCBI Life Tree : Ciona intestinalis

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

KIVMMVQMRI ALCVVFFINC AWSWESEPLA QEIAELLYSA SSGVDFEFGN ARQFSEEFST RQVLANPTAD TTSGEFTGSS TEQVHAFYSV PYAKPPVGMF RFKPPVAAEH GGSINVSVPN YAQCSQSPQQ CSDGTCGTTK TEDCLVLNIY APASVNLDST NNMNELLPVM FWIHGGAFFA GSGTNPGYDG GWLSNKTNTV VVNINYRLDA LGFLVFEEGD EKFDGNQGFK DQQLALKWVR DNIAKFGGDK NKVTIFGNSA GAQSVMLHVL SQESDPLFHR AIMQSNPAVF YYYTTDEAKV VTEELLDVLN CTTNKLDCLM NTEAHTLVNA RAKVMAKAAL RRNIFDGVEP YRPVTDGIEF IGQPLDQFQS GNWQKNKALI VGSNTEELEF INVVFRNRTV RKNSFEAVNN FVLGDYYGPI VSERYMQLAG ERPGAQYDYT AILAQEIGDM FFVCPSRALA RLASRSSPAS DTVYLYSNSH PADLGACTSE ASTCGHAYHG SEPRYVFNTV PNATADDMTV SDIFSDYWGS FAYTGYPQSD KYTAWPAYVP QSETIEGMSQ WTNILLKAPN SETETGYKED LCDFWDEIGF YVNITSPGDV TTLSTPVVSD VTEQAENEKT TVGSATMFGV TFNFTEKLMI AAGYFLFMMI NL

References

Title : Acetylcholinesterase from the invertebrate Ciona intestinalis is capable of assembling into asymmetric forms when co-expressed with vertebrate collagenic tail peptide - Frederick_2008_FEBS.J_275_1309
Author(s) : Frederick A , Tsigelny I , Cohenour F , Spiker C , Krejci E , Chatonnet A , Bourgoin S , Richards G , Allen T , Whitlock MH , Pezzementi L
Ref : Febs J , 275 :1309 , 2008
Abstract : Frederick_2008_FEBS.J_275_1309
ESTHER : Frederick_2008_FEBS.J_275_1309
PubMedSearch : Frederick_2008_FEBS.J_275_1309
PubMedID: 18279391
Gene_locus related to this paper: cioin-ACHE1 , cioin-ACHE2

Title : The draft genome of Ciona intestinalis: insights into chordate and vertebrate origins - Dehal_2002_Science_298_2157
Author(s) : Dehal P , Satou Y , Campbell RK , Chapman J , Degnan B , De Tomaso A , Davidson B , Di Gregorio A , Gelpke M , Goodstein DM , Harafuji N , Hastings KE , Ho I , Hotta K , Huang W , Kawashima T , Lemaire P , Martinez D , Meinertzhagen IA , Necula S , Nonaka M , Putnam N , Rash S , Saiga H , Satake M , Terry A , Yamada L , Wang HG , Awazu S , Azumi K , Boore J , Branno M , Chin-Bow S , DeSantis R , Doyle S , Francino P , Keys DN , Haga S , Hayashi H , Hino K , Imai KS , Inaba K , Kano S , Kobayashi K , Kobayashi M , Lee BI , Makabe KW , Manohar C , Matassi G , Medina M , Mochizuki Y , Mount S , Morishita T , Miura S , Nakayama A , Nishizaka S , Nomoto H , Ohta F , Oishi K , Rigoutsos I , Sano M , Sasaki A , Sasakura Y , Shoguchi E , Shin-I T , Spagnuolo A , Stainier D , Suzuki MM , Tassy O , Takatori N , Tokuoka M , Yagi K , Yoshizaki F , Wada S , Zhang C , Hyatt PD , Larimer F , Detter C , Doggett N , Glavina T , Hawkins T , Richardson P , Lucas S , Kohara Y , Levine M , Satoh N , Rokhsar DS
Ref : Science , 298 :2157 , 2002
Abstract : Dehal_2002_Science_298_2157
ESTHER : Dehal_2002_Science_298_2157
PubMedSearch : Dehal_2002_Science_298_2157
PubMedID: 12481130
Gene_locus related to this paper: cioin-141645 , cioin-147959 , cioin-150181 , cioin-154370 , cioin-ACHE1 , cioin-ACHE2 , cioin-cxest , cioin-f6qcp0 , cioin-f6r8z1 , cioin-f6u176 , cioin-f6vac9 , cioin-f6x584 , cioin-f6xa69 , cioin-f6y403 , cioin-h2xqb4 , cioin-H2XTI0 , cioin-F6T1M3 , cioin-H2XUP7 , cioin-CIN.7233 , cioin-F6V269 , cioin-Cin16330 , cioin-h2xua2 , cioin-f6vaa5 , cioin-f6v9x6 , cioin-f6swc9 , cioin-f7amz2 , cioin-f6s021 , cioin-h2xxq9 , cioin-h2xne6 , cioin-f6ynr2

Title : A cDNA resource from the basal chordate Ciona intestinalis -
Author(s) : Satou Y , Yamada L , Mochizuki Y , Takatori N , Kawashima T , Sasaki A , Hamaguchi M , Awazu S , Yagi K , Sasakura Y , Nakayama A , Ishikawa H , Inaba K , Satoh N
Ref : Genesis , 33 :153 , 2002
PubMedID: 12203911
Gene_locus related to this paper: cioin-141645 , cioin-147959 , cioin-150181 , cioin-154370 , cioin-ACHE1 , cioin-ACHE2 , cioin-cxest , cioin-F6V269