Homo sapiens (Human) LIPC hepatic triacylglycerol lipase HTGL
LIPC, which is synthesized in liver, is secreted and bound to hepatocytes and hepatic endothelial surfaces via heparin sulfate proteoglycans (HSPGs). Active LIPC exists as a homodimer and has broad substrate specificity, catalyzing the hydrolysis of fatty acyl chains at the sn-1 position of phospholipids and of mono-, di-, and triacylglycerols associated with a variety of lipoproteins, including high density lipoprotein (HDL). LIPC may also facilitate binding and uptake of lipoproteins and selective uptake of cholesteryl esters from lipoproteins (summary by Brown et al., 2004). (from OMIM) A Deficiency of HL is characterized by abnormally triglyceride-rich low and high density lipoproteins as well as beta-migrating very low density lipoproteins. Familial human hepatic lipase deficiency is a rare recessive disorder that results from mutations of the mature protein. The disease is characterised by premature atherosclerosis and abnormal circulating lipoproteins. One mutation (E97G) gives a gain of function phenotype and a different syndrome Hypobetalipoproteinemia
MDTSPLCFSI LLVLCIFIQS SALGQSLKPE PFGRRAQAVE TNKTLHEMKT RFLLFGETNQ GCQIRINHPD TLQECGFNSS LPLVMIIHGW SVDGVLENWI WQMVAALKSQ PAQPVNVGLV DWITLAHDHY TIAVRNTRLV GKEVAALLRW LEESVQLSRS HVHLIGYSLG AHVSGFAGSS IGGTHKIGRI TGLDAAGPLF EGSAPSNRLS PDDANFVDAI HTFTREHMGL SVGIKQPIGH YDFYPNGGSF QPGCHFLELY RHIAQHGFNA ITQTIKCSHE RSVHLFIDSL LHAGTQSMAY PCGDMNSFSQ GLCLSCKKGR CNTLGYHVRQ EPRSKSKRLF LVTRAQSPFK VYHYQLKIQF INQTETPIQT TFTMSLLGTK EKMQKIPITL GKGIASNKTY SFLITLDVDI GELIMIKFKW ENSAVWANVW DTVQTIIPWS TGPRHSGLVL KTIRVKAGET QQRMTFCSEN TDDLLLRPTQ EKIFVKCEIK SKTSKRKIR
| Title : Identification of a Gain-of-Function LIPC Variant as a Novel Cause of Familial Combined Hypocholesterolemia - Dijk_2022_Circulation__ |
| Author(s) : Dijk W , Di Filippo M , Kooijman S , van Eenige R , Rimbert A , Caillaud A , Thedrez A , Arnaud L , Pronk A , Garcon D , Sotin T , Lindenbaum P , Garcia EO , Pais de Barros JP , Duvillard L , Si-Tayeb K , Amigo N , Le Questel JY , Rensen PCN , Le May C , Moulin P , Cariou B |
| Ref : Circulation , : , 2022 |
| Abstract : Dijk_2022_Circulation__ |
| ESTHER : Dijk_2022_Circulation__ |
| PubMedSearch : Dijk_2022_Circulation__ |
| PubMedID: 35899625 |
| Gene_locus related to this paper: human-LIPC |
| Title : The -250G\/A and -514C\/T Polymorphisms in Hepatic Lipase Gene Promoter Confers an Increased Risk of Hepatocellular Carcinoma in a Chinese Population - Niu_2018_Ann.Hepatol_17_992 |
| Author(s) : Niu CZ , Zhang FH , Li Y , Liu JJ , Bao CX |
| Ref : Ann Hepatol , 17 :992 , 2018 |
| Abstract : Niu_2018_Ann.Hepatol_17_992 |
| ESTHER : Niu_2018_Ann.Hepatol_17_992 |
| PubMedSearch : Niu_2018_Ann.Hepatol_17_992 |
| PubMedID: 30600300 |
| Gene_locus related to this paper: human-LIPC |
| Title : Characterization of a peptide containing the major heparin binding domain of human hepatic lipase - Coady_2018_J.Pept.Sci__e3123 |
| Author(s) : Coady BM , Marshall JD , Hattie LE , Brannan AM , Fitzpatrick MN , Hickey KE , Wallin S , Booth V , Brown RJ |
| Ref : J Pept Sci , :e3123 , 2018 |
| Abstract : Coady_2018_J.Pept.Sci__e3123 |
| ESTHER : Coady_2018_J.Pept.Sci__e3123 |
| PubMedSearch : Coady_2018_J.Pept.Sci__e3123 |
| PubMedID: 30288870 |
| Gene_locus related to this paper: human-LIPC |
| Title : Hormone-sensitive lipase preferentially redistributes to lipid droplets associated with perilipin-5 in human skeletal muscle during moderate-intensity exercise - Whytock_2018_J.Physiol_596_2077 |
| Author(s) : Whytock KL , Shepherd SO , Wagenmakers AJM , Strauss JA |
| Ref : Journal de Physiologie , 596 :2077 , 2018 |
| Abstract : Whytock_2018_J.Physiol_596_2077 |
| ESTHER : Whytock_2018_J.Physiol_596_2077 |
| PubMedSearch : Whytock_2018_J.Physiol_596_2077 |
| PubMedID: 29527681 |
| Gene_locus related to this paper: human-LIPC |
| Title : Incidental finding of severe hypertriglyceridemia in children. Role of multiple rare variants in genes affecting plasma triglyceride - Buonuomo_2017_J.Clin.Lipidol_11_1329 |
| Author(s) : Buonuomo PS , Rabacchi C , Macchiaiolo M , Trenti C , Fasano T , Tarugi P , Bartuli A , Bertolini S , Calandra S |
| Ref : J Clin Lipidol , 11 :1329 , 2017 |
| Abstract : Buonuomo_2017_J.Clin.Lipidol_11_1329 |
| ESTHER : Buonuomo_2017_J.Clin.Lipidol_11_1329 |
| PubMedSearch : Buonuomo_2017_J.Clin.Lipidol_11_1329 |
| PubMedID: 28951076 |
| Gene_locus related to this paper: human-LIPC , human-LPL |
| Title : The role of plasma lipoprotein lipase, hepatic lipase and GPIHBP1 in the metabolism of remnant lipoproteins and small dense LDL in patients with coronary artery disease - Muraba_2017_Clin.Chim.Acta_476_146 |
| Author(s) : Muraba Y , Koga T , Shimomura Y , Ito Y , Hirao Y , Kobayashi J , Kimura T , Nakajima K , Murakami M |
| Ref : Clinica Chimica Acta , 476 :146 , 2017 |
| Abstract : Muraba_2017_Clin.Chim.Acta_476_146 |
| ESTHER : Muraba_2017_Clin.Chim.Acta_476_146 |
| PubMedSearch : Muraba_2017_Clin.Chim.Acta_476_146 |
| PubMedID: 29174344 |
| Gene_locus related to this paper: human-LIPC , human-LPL |
| Title : The Contribution of GWAS Loci in Familial Dyslipidemias - Ripatti_2016_PLoS.Genet_12_e1006078 |
| Author(s) : Ripatti P , Ramo JT , Soderlund S , Surakka I , Matikainen N , Pirinen M , Pajukanta P , Sarin AP , Service SK , Laurila PP , Ehnholm C , Salomaa V , Wilson RK , Palotie A , Freimer NB , Taskinen MR , Ripatti S |
| Ref : PLoS Genet , 12 :e1006078 , 2016 |
| Abstract : Ripatti_2016_PLoS.Genet_12_e1006078 |
| ESTHER : Ripatti_2016_PLoS.Genet_12_e1006078 |
| PubMedSearch : Ripatti_2016_PLoS.Genet_12_e1006078 |
| PubMedID: 27227539 |
| Gene_locus related to this paper: human-LIPC |
| Title : Role of SN1 lipases on plasma lipids in metabolic syndrome and obesity - Miksztowicz_2014_Arterioscler.Thromb.Vasc.Biol_34_669 |
| Author(s) : Miksztowicz V , Schreier L , McCoy M , Lucero D , Fassio E , Billheimer J , Rader DJ , Berg G |
| Ref : Arterioscler Thromb Vasc Biol , 34 :669 , 2014 |
| Abstract : Miksztowicz_2014_Arterioscler.Thromb.Vasc.Biol_34_669 |
| ESTHER : Miksztowicz_2014_Arterioscler.Thromb.Vasc.Biol_34_669 |
| PubMedSearch : Miksztowicz_2014_Arterioscler.Thromb.Vasc.Biol_34_669 |
| PubMedID: 24458708 |
| Gene_locus related to this paper: human-LIPC , human-LPL , human-LIPG |
| Title : Lipidomic analyses of female mice lacking hepatic lipase and endothelial lipase indicate selective modulation of plasma lipid species - Yang_2014_Lipids_49_505 |
| Author(s) : Yang Y , Kuwano T , Lagor WR , Albert CJ , Brenton S , Rader DJ , Ford DA , Brown RJ |
| Ref : Lipids , 49 :505 , 2014 |
| Abstract : Yang_2014_Lipids_49_505 |
| ESTHER : Yang_2014_Lipids_49_505 |
| PubMedSearch : Yang_2014_Lipids_49_505 |
| PubMedID: 24777581 |
| Gene_locus related to this paper: human-LIPC , human-LIPG |
| Title : An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome - Bian_2014_J.Proteomics_96_253 |
| Author(s) : Bian Y , Song C , Cheng K , Dong M , Wang F , Huang J , Sun D , Wang L , Ye M , Zou H |
| Ref : J Proteomics , 96 :253 , 2014 |
| Abstract : Bian_2014_J.Proteomics_96_253 |
| ESTHER : Bian_2014_J.Proteomics_96_253 |
| PubMedSearch : Bian_2014_J.Proteomics_96_253 |
| PubMedID: 24275569 |
| Gene_locus related to this paper: human-LIPC |
| Title : Functional characterization of novel variants in the CETP promoter and the LIPC gene in subjects with hyperalphalipoproteinemia - Plengpanich_2013_Clin.Chim.Acta_416_92 |
| Author(s) : Plengpanich W , Tongkobpetch S , Shotelersuk V , Le Goff W , Khovidhunkit W |
| Ref : Clinica Chimica Acta , 416 :92 , 2013 |
| Abstract : Plengpanich_2013_Clin.Chim.Acta_416_92 |
| ESTHER : Plengpanich_2013_Clin.Chim.Acta_416_92 |
| PubMedSearch : Plengpanich_2013_Clin.Chim.Acta_416_92 |
| PubMedID: 23219720 |
| Gene_locus related to this paper: human-LIPC |
| Title : The -514C\/T Polymorphism of Hepatic Lipase Gene among Iranian Patients with Coronary Heart Disease - Ghatreh_2012_Iran.J.Public.Health_41_59 |
| Author(s) : Ghatreh Samani K , Noori M , Nobar MR , Chaleshtory MH , Farrokhi E , Amin MD |
| Ref : Iran J Public Health , 41 :59 , 2012 |
| Abstract : Ghatreh_2012_Iran.J.Public.Health_41_59 |
| ESTHER : Ghatreh_2012_Iran.J.Public.Health_41_59 |
| PubMedSearch : Ghatreh_2012_Iran.J.Public.Health_41_59 |
| PubMedID: 23113123 |
| Gene_locus related to this paper: human-LIPC |
| Title : Resequencing CETP, LIPC and LIPG genes in Thai subjects with hyperalphalipoproteinemia - Khovidhunkit_2012_Am.J.Cardiol_110_62 |
| Author(s) : Khovidhunkit W , Chartyingcharoen P , Siriwong S , Limumpornpetch P , Plengpanich W |
| Ref : American Journal of Cardiology , 110 :62 , 2012 |
| Abstract : Khovidhunkit_2012_Am.J.Cardiol_110_62 |
| ESTHER : Khovidhunkit_2012_Am.J.Cardiol_110_62 |
| PubMedSearch : Khovidhunkit_2012_Am.J.Cardiol_110_62 |
| PubMedID: 22464213 |
| Gene_locus related to this paper: human-LIPC |
| Title : Role of hepatic lipase and endothelial lipase in high-density lipoprotein-mediated reverse cholesterol transport - Annema_2011_Curr.Atheroscler.Rep_13_257 |
| Author(s) : Annema W , Tietge UJ |
| Ref : Curr Atheroscler Rep , 13 :257 , 2011 |
| Abstract : Annema_2011_Curr.Atheroscler.Rep_13_257 |
| ESTHER : Annema_2011_Curr.Atheroscler.Rep_13_257 |
| PubMedSearch : Annema_2011_Curr.Atheroscler.Rep_13_257 |
| PubMedID: 21424685 |
| Gene_locus related to this paper: human-LIPC , human-LIPG |
| Title : Hepatic lipase deficiency in a Middle-Eastern-Arabic male. - Al Riyami_2010_BMJ.Case.Rep__ |
| Author(s) : Al Riyami N , Al-Ali AM , Al-Sarraf AJ , Hill J , Sachs-Barrable K , Hegele R , Wasan KM , Frohlich J |
| Ref : BMJ Case Rep , : , 2010 |
| Abstract : Al Riyami_2010_BMJ.Case.Rep__ |
| ESTHER : Al Riyami_2010_BMJ.Case.Rep__ |
| PubMedSearch : Al Riyami_2010_BMJ.Case.Rep__ |
| PubMedID: 22798447 |
| Gene_locus related to this paper: human-LIPC |
| Title : Polymorphisms in the hepatic lipase gene affect plasma HDL-cholesterol levels in a Turkish population - Hodoglugil_2010_J.Lipid.Res_51_422 |
| Author(s) : Hodoglugil U , Williamson DW , Mahley RW |
| Ref : J Lipid Res , 51 :422 , 2010 |
| Abstract : Hodoglugil_2010_J.Lipid.Res_51_422 |
| ESTHER : Hodoglugil_2010_J.Lipid.Res_51_422 |
| PubMedSearch : Hodoglugil_2010_J.Lipid.Res_51_422 |
| PubMedID: 19734193 |
| Gene_locus related to this paper: human-LIPC |
| Title : Impact of combined deficiency of hepatic lipase and endothelial lipase on the metabolism of both high-density lipoproteins and apolipoprotein B-containing lipoproteins - Brown_2010_Circ.Res_107_357 |
| Author(s) : Brown RJ , Lagor WR , Sankaranaravanan S , Yasuda T , Quertermous T , Rothblat GH , Rader DJ |
| Ref : Circulation Research , 107 :357 , 2010 |
| Abstract : Brown_2010_Circ.Res_107_357 |
| ESTHER : Brown_2010_Circ.Res_107_357 |
| PubMedSearch : Brown_2010_Circ.Res_107_357 |
| PubMedID: 20558822 |
| Gene_locus related to this paper: human-LIPC , human-LIPG |
| Title : LIPC variants in the promoter and intron 1 modify HDL-C levels in a sex-specific fashion - Feitosa_2009_Atherosclerosis_204_171 |
| Author(s) : Feitosa MF , Myers RH , Pankow JS , Province MA , Borecki IB |
| Ref : Atherosclerosis , 204 :171 , 2009 |
| Abstract : Feitosa_2009_Atherosclerosis_204_171 |
| ESTHER : Feitosa_2009_Atherosclerosis_204_171 |
| PubMedSearch : Feitosa_2009_Atherosclerosis_204_171 |
| PubMedID: 19101670 |
| Gene_locus related to this paper: human-LIPC |
| Title : Two novel mutations and functional analyses of the CETP and LIPC genes underlying severe hyperalphalipoproteinemia - Plengpanich_2009_Metabolism_58_1178 |
| Author(s) : Plengpanich W , Siriwong S , Khovidhunkit W |
| Ref : Metabolism , 58 :1178 , 2009 |
| Abstract : Plengpanich_2009_Metabolism_58_1178 |
| ESTHER : Plengpanich_2009_Metabolism_58_1178 |
| PubMedSearch : Plengpanich_2009_Metabolism_58_1178 |
| PubMedID: 19428034 |
| Gene_locus related to this paper: human-LIPC |
| Title : [Association of the hepatic lipase gene -250G\/A promoter polymorphism with the susceptibility to type 2 diabetes mellitus combining with coronary heart disease] - Wei_2009_Zhonghua.Yi.Xue.Yi.Chuan.Xue.Za.Zhi_26_219 |
| Author(s) : Wei M , Lu YS , Li PP |
| Ref : Zhonghua Yi Xue Yi Chuan Xue Za Zhi , 26 :219 , 2009 |
| Abstract : Wei_2009_Zhonghua.Yi.Xue.Yi.Chuan.Xue.Za.Zhi_26_219 |
| ESTHER : Wei_2009_Zhonghua.Yi.Xue.Yi.Chuan.Xue.Za.Zhi_26_219 |
| PubMedSearch : Wei_2009_Zhonghua.Yi.Xue.Yi.Chuan.Xue.Za.Zhi_26_219 |
| PubMedID: 19350521 |
| Gene_locus related to this paper: human-LIPC |
| Title : Combined hepatic lipase -514C\/T and cholesteryl ester transfer protein I405V polymorphisms are associated with the risk of coronary artery disease - Ghatrehsamani_2009_Genet.Test.Mol.Biomarkers_13_809 |
| Author(s) : Ghatrehsamani K , Darabi M , Rahbani M , Hashemzadeh Chaleshtory M , Farrokhi E , Noori M |
| Ref : Genet Test Mol Biomarkers , 13 :809 , 2009 |
| Abstract : Ghatrehsamani_2009_Genet.Test.Mol.Biomarkers_13_809 |
| ESTHER : Ghatrehsamani_2009_Genet.Test.Mol.Biomarkers_13_809 |
| PubMedSearch : Ghatrehsamani_2009_Genet.Test.Mol.Biomarkers_13_809 |
| PubMedID: 19810818 |
| Gene_locus related to this paper: human-LIPC |
| Title : Association of the -250G\/A promoter polymorphism of the hepatic lipase gene with the risk of peripheral arterial disease in type 2 diabetic patients - Valdivielso_2008_J.Diabetes.Complications_22_273 |
| Author(s) : Valdivielso P , Ariza MJ , de la Vega-Roman C , Gonzalez-Alegre T , Rioja J , Ulzurrun E , Gonzalez-Santos P |
| Ref : J Diabetes Complications , 22 :273 , 2008 |
| Abstract : Valdivielso_2008_J.Diabetes.Complications_22_273 |
| ESTHER : Valdivielso_2008_J.Diabetes.Complications_22_273 |
| PubMedSearch : Valdivielso_2008_J.Diabetes.Complications_22_273 |
| PubMedID: 18413186 |
| Gene_locus related to this paper: human-LIPC |
| Title : The -250G>A promoter variant in hepatic lipase associates with elevated fasting serum high-density lipoprotein cholesterol modulated by interaction with physical activity in a study of 16,156 Danish subjects - Grarup_2008_J.Clin.Endocrinol.Metab_93_2294 |
| Author(s) : Grarup N , Andreasen CH , Andersen MK , Albrechtsen A , Sandbaek A , Lauritzen T , Borch-Johnsen K , Jorgensen T , Schmitz O , Hansen T , Pedersen O |
| Ref : J Clinical Endocrinology Metab , 93 :2294 , 2008 |
| Abstract : Grarup_2008_J.Clin.Endocrinol.Metab_93_2294 |
| ESTHER : Grarup_2008_J.Clin.Endocrinol.Metab_93_2294 |
| PubMedSearch : Grarup_2008_J.Clin.Endocrinol.Metab_93_2294 |
| PubMedID: 18364377 |
| Gene_locus related to this paper: human-LIPC |
| Title : Hepatic lipase gene -514C\/T polymorphism in the Guangxi Hei Yi Zhuang and Han populations - Wu_2008_Lipids_43_733 |
| Author(s) : Wu J , Yin R , Lin W , Pan S , Yang D |
| Ref : Lipids , 43 :733 , 2008 |
| Abstract : Wu_2008_Lipids_43_733 |
| ESTHER : Wu_2008_Lipids_43_733 |
| PubMedSearch : Wu_2008_Lipids_43_733 |
| PubMedID: 18592285 |
| Gene_locus related to this paper: human-LIPC |
| Title : The -250G\/A polymorphism in the hepatic lipase gene promoter influences the postprandial lipemic response in healthy men - Jimenez-Gomez_2008_Nutr.Metab.Cardiovasc.Dis_18_173 |
| Author(s) : Jimenez-Gomez Y , Perez-Jimenez F , Marin C , Gomez P , Moreno R , Delgado J , Perez-Martinez P , Gomez MJ , Lopez-Miranda J |
| Ref : Nutr Metab Cardiovasc Dis , 18 :173 , 2008 |
| Abstract : Jimenez-Gomez_2008_Nutr.Metab.Cardiovasc.Dis_18_173 |
| ESTHER : Jimenez-Gomez_2008_Nutr.Metab.Cardiovasc.Dis_18_173 |
| PubMedSearch : Jimenez-Gomez_2008_Nutr.Metab.Cardiovasc.Dis_18_173 |
| PubMedID: 17399967 |
| Gene_locus related to this paper: human-LIPC |
| Title : [Association of hepatic lipase gene promoter polymorphism -514C\/T with nonalcoholic fatty liver disease] - Zhan_2008_Zhonghua.Gan.Zang.Bing.Za.Zhi_16_375 |
| Author(s) : Zhan Q , Li YY , Nie YQ , Zhou YJ , Du YL , Sha WH , Wang H |
| Ref : Zhonghua Gan Zang Bing Za Zhi , 16 :375 , 2008 |
| Abstract : Zhan_2008_Zhonghua.Gan.Zang.Bing.Za.Zhi_16_375 |
| ESTHER : Zhan_2008_Zhonghua.Gan.Zang.Bing.Za.Zhi_16_375 |
| PubMedSearch : Zhan_2008_Zhonghua.Gan.Zang.Bing.Za.Zhi_16_375 |
| PubMedID: 18510853 |
| Gene_locus related to this paper: human-LIPC |
| Title : Association of sixty-one non-synonymous polymorphisms in forty-one hypertension candidate genes with blood pressure variation and hypertension - Kokubo_2006_Hypertens.Res_29_611 |
| Author(s) : Kokubo Y , Tomoike H , Tanaka C , Banno M , Okuda T , Inamoto N , Kamide K , Kawano Y , Miyata T |
| Ref : Hypertens Res , 29 :611 , 2006 |
| Abstract : Kokubo_2006_Hypertens.Res_29_611 |
| ESTHER : Kokubo_2006_Hypertens.Res_29_611 |
| PubMedSearch : Kokubo_2006_Hypertens.Res_29_611 |
| PubMedID: 17137217 |
| Gene_locus related to this paper: human-LIPC |
| Title : The -514C\/T polymorphism of the hepatic lipase gene significantly modulates the HDL-cholesterol response to statin treatment - Lahoz_2005_Atherosclerosis_182_129 |
| Author(s) : Lahoz C , Pena R , Mostaza JM , Laguna F , Garcia-Iglesias MF , Taboada M , Pinto X |
| Ref : Atherosclerosis , 182 :129 , 2005 |
| Abstract : Lahoz_2005_Atherosclerosis_182_129 |
| ESTHER : Lahoz_2005_Atherosclerosis_182_129 |
| PubMedSearch : Lahoz_2005_Atherosclerosis_182_129 |
| PubMedID: 16115483 |
| Gene_locus related to this paper: human-LIPC |
| Title : Effect of fenofibrate on plasma lipoprotein composition and kinetics in patients with complete hepatic lipase deficiency - Ruel_2005_Arterioscler.Thromb.Vasc.Biol_25_2600 |
| Author(s) : Ruel IL , Lamarche B , Mauger JF , Badellino KO , Cohn JS , Marcil M , Couture P |
| Ref : Arterioscler Thromb Vasc Biol , 25 :2600 , 2005 |
| Abstract : Ruel_2005_Arterioscler.Thromb.Vasc.Biol_25_2600 |
| ESTHER : Ruel_2005_Arterioscler.Thromb.Vasc.Biol_25_2600 |
| PubMedSearch : Ruel_2005_Arterioscler.Thromb.Vasc.Biol_25_2600 |
| PubMedID: 16224048 |
| Gene_locus related to this paper: human-LIPC |
| Title : Association between -250G\/A polymorphism of the hepatic lipase gene promoter and coronary artery disease and HDL-C levels in a Southern Brazilian population - de Andrade_2004_Clin.Genet_65_390 |
| Author(s) : de Andrade FM , Silveira FR , Arsand M , Antunes AL , Torres MR , Zago AJ , Callegari-Jaques SM , Hutz MH |
| Ref : Clin Genet , 65 :390 , 2004 |
| Abstract : de Andrade_2004_Clin.Genet_65_390 |
| ESTHER : de Andrade_2004_Clin.Genet_65_390 |
| PubMedSearch : de Andrade_2004_Clin.Genet_65_390 |
| PubMedID: 15099346 |
| Gene_locus related to this paper: human-LIPC |
| Title : Characterization of a novel mutation causing hepatic lipase deficiency among French Canadians - Ruel_2003_J.Lipid.Res_44_1508 |
| Author(s) : Ruel IL , Couture P , Gagne C , Deshaies Y , Simard J , Hegele RA , Lamarche B |
| Ref : J Lipid Res , 44 :1508 , 2003 |
| Abstract : Ruel_2003_J.Lipid.Res_44_1508 |
| ESTHER : Ruel_2003_J.Lipid.Res_44_1508 |
| PubMedSearch : Ruel_2003_J.Lipid.Res_44_1508 |
| PubMedID: 12777476 |
| Gene_locus related to this paper: human-LIPC |
| Title : Evidence that hepatic lipase and endothelial lipase have different substrate specificities for high-density lipoprotein phospholipids - Duong_2003_Biochemistry_42_13778 |
| Author(s) : Duong M , Psaltis M , Rader DJ , Marchadier D , Barter PJ , Rye KA |
| Ref : Biochemistry , 42 :13778 , 2003 |
| Abstract : Duong_2003_Biochemistry_42_13778 |
| ESTHER : Duong_2003_Biochemistry_42_13778 |
| PubMedSearch : Duong_2003_Biochemistry_42_13778 |
| PubMedID: 14622025 |
| Gene_locus related to this paper: human-LIPC , human-LIPG |
| Title : Association of extreme blood lipid profile phenotypic variation with 11 reverse cholesterol transport genes and 10 non-genetic cardiovascular disease risk factors - Morabia_2003_Hum.Mol.Genet_12_2733 |
| Author(s) : Morabia A , Cayanis E , Costanza MC , Ross BM , Flaherty MS , Alvin GB , Das K , Gilliam TC |
| Ref : Hum Mol Genet , 12 :2733 , 2003 |
| Abstract : Morabia_2003_Hum.Mol.Genet_12_2733 |
| ESTHER : Morabia_2003_Hum.Mol.Genet_12_2733 |
| PubMedSearch : Morabia_2003_Hum.Mol.Genet_12_2733 |
| PubMedID: 12966036 |
| Gene_locus related to this paper: human-LIPC |
| Title : The V73M mutation in the hepatic lipase gene is associated with elevated cholesterol levels in four Dutch pedigrees with familial combined hyperlipidemia - Hoffer_2000_Atherosclerosis_151_443 |
| Author(s) : Hoffer MJ , Snieder H , Bredie SJ , Demacker PN , Kastelein JJ , Frants RR , Stalenhoef AF |
| Ref : Atherosclerosis , 151 :443 , 2000 |
| Abstract : Hoffer_2000_Atherosclerosis_151_443 |
| ESTHER : Hoffer_2000_Atherosclerosis_151_443 |
| PubMedSearch : Hoffer_2000_Atherosclerosis_151_443 |
| PubMedID: 10924721 |
| Gene_locus related to this paper: human-LIPC |
| Title : Characterization of single-nucleotide polymorphisms in coding regions of human genes - Cargill_1999_Nat.Genet_22_231 |
| Author(s) : Cargill M , Altshuler D , Ireland J , Sklar P , Ardlie K , Patil N , Shaw N , Lane CR , Lim EP , Kalyanaraman N , Nemesh J , Ziaugra L , Friedland L , Rolfe A , Warrington J , Lipshutz R , Daley GQ , Lander ES |
| Ref : Nat Genet , 22 :231 , 1999 |
| Abstract : Cargill_1999_Nat.Genet_22_231 |
| ESTHER : Cargill_1999_Nat.Genet_22_231 |
| PubMedSearch : Cargill_1999_Nat.Genet_22_231 |
| PubMedID: 10391209 |
| Gene_locus related to this paper: human-LIPC |
| Title : Hepatic lipase: new insights from genetic and metabolic studies - Cohen_1999_Curr.Opin.Lipidol_10_259 |
| Author(s) : Cohen JC , Vega GL , Grundy SM |
| Ref : Curr Opin Lipidol , 10 :259 , 1999 |
| Abstract : Cohen_1999_Curr.Opin.Lipidol_10_259 |
| ESTHER : Cohen_1999_Curr.Opin.Lipidol_10_259 |
| PubMedSearch : Cohen_1999_Curr.Opin.Lipidol_10_259 |
| PubMedID: 10431662 |
| Gene_locus related to this paper: human-LIPC |
| Title : 18 bp Insertion\/Duplication With Internal Missense Mutation in Human Hepatic Lipase Gene Exon 3. - |
| Author(s) : Tiebel O , Gehrisch S , Pietzsch J , Gromeier S , Jaross W |
| Ref : Hum Mutat , 12 :216 , 1998 |
| PubMedID: 10660332 |
| Gene_locus related to this paper: human-LIPC |
| Title : A hepatic lipase (LIPC) allele associated with high plasma concentrations of high density lipoprotein cholesterol - Guerra_1997_Proc.Natl.Acad.Sci.U.S.A_94_4532 |
| Author(s) : Guerra R , Wang J , Grundy SM , Cohen JC |
| Ref : Proc Natl Acad Sci U S A , 94 :4532 , 1997 |
| Abstract : Guerra_1997_Proc.Natl.Acad.Sci.U.S.A_94_4532 |
| ESTHER : Guerra_1997_Proc.Natl.Acad.Sci.U.S.A_94_4532 |
| PubMedSearch : Guerra_1997_Proc.Natl.Acad.Sci.U.S.A_94_4532 |
| PubMedID: 9114024 |
| Gene_locus related to this paper: human-LIPC |
| Title : Heterozygous hepatic lipase deficiency, due to two missense mutations R186H and L334F, in the HL gene - Knudsen_1997_Atherosclerosis_128_165 |
| Author(s) : Knudsen P , Antikainen M , Uusi-Oukari M , Ehnholm S , Lahdenpera S , Bensadoun A , Funke H , Wiebusch H , Assmann G , Taskinen MR , Ehnholm C |
| Ref : Atherosclerosis , 128 :165 , 1997 |
| Abstract : Knudsen_1997_Atherosclerosis_128_165 |
| ESTHER : Knudsen_1997_Atherosclerosis_128_165 |
| PubMedSearch : Knudsen_1997_Atherosclerosis_128_165 |
| PubMedID: 9050773 |
| Gene_locus related to this paper: human-LIPC |
| Title : An AvaII polymorphism in exon 5 of the human hepatic triglyceride lipase gene - |
| Author(s) : Mori A , Takagi A , Ikeda Y , Ashida Y , Yamamoto A |
| Ref : Mol Cell Probes , 10 :309 , 1996 |
| PubMedID: 8865179 |
| Gene_locus related to this paper: human-LIPC |
| Title : Identification of a BstNI polymorphism in exon 9 of the human hepatic triglyceride lipase gene - |
| Author(s) : Takagi A , Ikeda Y , Mori A , Ashida Y , Yamamoto A |
| Ref : Mol Cell Probes , 10 :313 , 1996 |
| PubMedID: 8865180 |
| Gene_locus related to this paper: human-LIPC |
| Title : Isolation and characterization of the human hepatic lipase gene - Ameis_1990_J.Biol.Chem_265_6552 |
| Author(s) : Ameis D , Stahnke G , Kobayashi J , McLean J , Lee G , Buscher M , Schotz MC , Will H |
| Ref : Journal of Biological Chemistry , 265 :6552 , 1990 |
| Abstract : Ameis_1990_J.Biol.Chem_265_6552 |
| ESTHER : Ameis_1990_J.Biol.Chem_265_6552 |
| PubMedSearch : Ameis_1990_J.Biol.Chem_265_6552 |
| PubMedID: 2324091 |
| Gene_locus related to this paper: human-LIPC |
| Title : Structure of the human hepatic triglyceride lipase gene - Cai_1989_Biochemistry_28_8966 |
| Author(s) : Cai SJ , Wong DM , Chen SH , Chan L |
| Ref : Biochemistry , 28 :8966 , 1989 |
| Abstract : Cai_1989_Biochemistry_28_8966 |
| ESTHER : Cai_1989_Biochemistry_28_8966 |
| PubMedSearch : Cai_1989_Biochemistry_28_8966 |
| PubMedID: 2605236 |
| Gene_locus related to this paper: human-LIPC |
| Title : Isolation and cDNA sequence of human postheparin plasma hepatic triglyceride lipase - Martin_1988_J.Biol.Chem_263_10907 |
| Author(s) : Martin GA , Busch SJ , Meredith GD , Cardin AD , Blankenship DT , Mao SJ , Rechtin AE , Woods CW , Racke MM , Schafer MP , Fitzgerald MC , Burke DM , Flanagan MA , Jackson RL |
| Ref : Journal of Biological Chemistry , 263 :10907 , 1988 |
| Abstract : Martin_1988_J.Biol.Chem_263_10907 |
| ESTHER : Martin_1988_J.Biol.Chem_263_10907 |
| PubMedSearch : Martin_1988_J.Biol.Chem_263_10907 |
| PubMedID: 2839510 |
| Gene_locus related to this paper: human-LIPC |
| Title : Human hepatic lipase. Cloned cDNA sequence, restriction fragment length polymorphisms, chromosomal localization, and evolutionary relationships with lipoprotein lipase and pancreatic lipase - Datta_1988_J.Biol.Chem_263_1107 |
| Author(s) : Datta S , Luo CC , Li WH , VanTuinen P , Ledbetter DH , Brown MA , Chen SH , Liu SW , Chan L |
| Ref : Journal of Biological Chemistry , 263 :1107 , 1988 |
| Abstract : Datta_1988_J.Biol.Chem_263_1107 |
| ESTHER : Datta_1988_J.Biol.Chem_263_1107 |
| PubMedSearch : Datta_1988_J.Biol.Chem_263_1107 |
| PubMedID: 2447084 |
| Gene_locus related to this paper: human-LIPC |
| Title : Human hepatic triglyceride lipase: cDNA cloning, amino acid sequence and expression in a cultured cell line - Stahnke_1987_Differentiation_35_45 |
| Author(s) : Stahnke G , Sprengel R , Augustin J , Will H |
| Ref : Differentiation , 35 :45 , 1987 |
| Abstract : Stahnke_1987_Differentiation_35_45 |
| ESTHER : Stahnke_1987_Differentiation_35_45 |
| PubMedSearch : Stahnke_1987_Differentiation_35_45 |
| PubMedID: 2828141 |
| Gene_locus related to this paper: human-LIPC |
| Title : Preparation, characterization, and measurement of hepatic lipase - |
| Author(s) : Ehnholm C , Kuusi T |
| Ref : Methods Enzymol , 129 :716 , 1986 |
| PubMedID: 3724551 |
| Gene_locus related to this paper: human-LIPC |