human-LYPLA2

Homo sapiens (Human) acyl-protein thioesterase dJ886K2.4 lysophospholipase II APT2

Comment

another gene human-apthio2 DJ570F3.6 OldTrembl Q9UGE0 Ncbi_pid 6624592 ENSG00000206168 situated very close is a processed pseudo gene

Relationship

Family : LYsophospholipase_carboxylesterase

Block : X

Position in NCBI Life Tree : Homo sapiens

Molecular evidence

No mutation

No kinetic

No disease

Sequence

Peptide

MCGNTMSVPL LTDAATVSGA ERETAAVIFL HGLGDTGHSW ADALSTIRLP HVKYICPHAP RIPVTLNMKM VMPSWFDLMG LSPDAPEDEA GIKKAAENIK ALIEHEMKNG IPANRIVLGG FSQGGALSLY TALTCPHPLA GIVALSCWLP LHRAFPQAAN GSAKDLAILQ CHGELDPMVP VRFGALTAEK LRSVVTPARV QFKTYPGVMH SSCPQEMAAV KEFLEKLLPP V

References

Title : Palmitoylated acyl protein thioesterase APT2 deforms membranes to extract substrate acyl chains - Abrami_2021_Nat.Chem.Biol_17_438
Author(s) : Abrami L , Audagnotto M , Ho S , Marcaida MJ , Mesquita FS , Anwar MU , Sandoz PA , Fonti G , Pojer F , Dal Peraro M , van der Goot FG
Ref : Nat Chemical Biology , 17 :438 , 2021
Abstract : Abrami_2021_Nat.Chem.Biol_17_438
ESTHER : Abrami_2021_Nat.Chem.Biol_17_438
PubMedSearch : Abrami_2021_Nat.Chem.Biol_17_438
PubMedID: 33707782
Gene_locus related to this paper: human-LYPLA1 , human-LYPLA2

Title : Human leukocytes differentially express endocannabinoid-glycerol lipases and hydrolyze 2-arachidonoyl-glycerol and its metabolites from the 15-lipoxygenase and cyclooxygenase pathways - Turcotte_2019_J.Leukoc.Biol_106_1337
Author(s) : Turcotte C , Dumais E , Archambault AS , Martin C , Blanchet MR , Bissonnette E , Boulet LP , Laviolette M , Di Marzo V , Flamand N
Ref : J Leukoc Biol , 106 :1337 , 2019
Abstract : Turcotte_2019_J.Leukoc.Biol_106_1337
ESTHER : Turcotte_2019_J.Leukoc.Biol_106_1337
PubMedSearch : Turcotte_2019_J.Leukoc.Biol_106_1337
PubMedID: 31556464
Gene_locus related to this paper: human-ABHD6 , human-ABHD12 , human-ABHD16A , human-CES1 , human-LYPLA2 , human-PPT1

Title : Lysophospholipases cooperate to mediate lipid homeostasis and lysophospholipid signaling - Wepy_2019_J.Lipid.Res_60_360
Author(s) : Wepy JA , Galligan JJ , Kingsley PJ , Xu S , Goodman MC , Tallman KA , Rouzer CA , Marnett LJ
Ref : J Lipid Res , 60 :360 , 2019
Abstract : Wepy_2019_J.Lipid.Res_60_360
ESTHER : Wepy_2019_J.Lipid.Res_60_360
PubMedSearch : Wepy_2019_J.Lipid.Res_60_360
PubMedID: 30482805
Gene_locus related to this paper: human-LYPLA2

Title : Molecular Mechanism for Isoform-Selective Inhibition of Acyl Protein Thioesterases 1 and 2 (APT1 and APT2) - Won_2016_ACS.Chem.Biol_11_3374
Author(s) : Won SJ , Davda D , Labby KJ , Hwang SY , Pricer R , Majmudar JD , Armacost KA , Rodriguez LA , Rodriguez CL , Chong FS , Torossian KA , Palakurthi J , Hur ES , Meagher JL , Brooks CL, 3rd , Stuckey JA , Martin BR
Ref : ACS Chemical Biology , 11 :3374 , 2016
Abstract : Won_2016_ACS.Chem.Biol_11_3374
ESTHER : Won_2016_ACS.Chem.Biol_11_3374
PubMedSearch : Won_2016_ACS.Chem.Biol_11_3374
PubMedID: 27748579
Gene_locus related to this paper: human-LYPLA2

Title : Identification of the major prostaglandin glycerol ester hydrolase in human cancer cells - Manna_2014_J.Biol.Chem_289_33741
Author(s) : Manna JD , Wepy JA , Hsu KL , Chang JW , Cravatt BF , Marnett LJ
Ref : Journal of Biological Chemistry , 289 :33741 , 2014
Abstract : Manna_2014_J.Biol.Chem_289_33741
ESTHER : Manna_2014_J.Biol.Chem_289_33741
PubMedSearch : Manna_2014_J.Biol.Chem_289_33741
PubMedID: 25301951
Gene_locus related to this paper: human-LYPLA2

Title : Identification of acyl protein thioesterases 1 and 2 as the cellular targets of the Ras-signaling modulators palmostatin B and M - Rusch_2011_Angew.Chem.Int.Ed.Engl_50_9838
Author(s) : Rusch M , Zimmermann TJ , Burger M , Dekker FJ , Gormer K , Triola G , Brockmeyer A , Janning P , Bottcher T , Sieber SA , Vetter IR , Hedberg C , Waldmann H
Ref : Angew Chem Int Ed Engl , 50 :9838 , 2011
Abstract : Rusch_2011_Angew.Chem.Int.Ed.Engl_50_9838
ESTHER : Rusch_2011_Angew.Chem.Int.Ed.Engl_50_9838
PubMedSearch : Rusch_2011_Angew.Chem.Int.Ed.Engl_50_9838
PubMedID: 21905186
Gene_locus related to this paper: human-LYPLA1 , human-LYPLA2

Title : Acyl-protein thioesterase 2 catalyzes the deacylation of peripheral membrane-associated GAP-43 - Tomatis_2010_PLoS.One_5_e15045
Author(s) : Tomatis VM , Trenchi A , Gomez GA , Daniotti JL
Ref : PLoS ONE , 5 :e15045 , 2010
Abstract : Tomatis_2010_PLoS.One_5_e15045
ESTHER : Tomatis_2010_PLoS.One_5_e15045
PubMedSearch : Tomatis_2010_PLoS.One_5_e15045
PubMedID: 21152083
Gene_locus related to this paper: human-LYPLA2