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hypsb-hpm3

Hypomyces subiculosus (Nectria subiculosa). Hypothemycin biosynthesis cluster protein hpm3. Thioesterase domain

Comment

Relationship

Family : Thioesterase

Block : X

Position in NCBI Life Tree : Hypomyces subiculosus

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

PVKTEVKKIS SSESELFHTI LESIAKETGT QVSDFTDDME LAELGVDSIM GIEIAAGVSS RTGLDVLLPS FVVDYPTIGD LRNEFARSST STPPSKTFSE FSIVDATPES TRSSSRAPSE KKEPAPASEK SEELVIVPSA VVEDSSPLPS ARITLIQGRS SSGKQPFYLI ADGAGSIATY IHLAPFKDKR PVYGIDSPFL RCPSRLTTQV GIEGVAKIIF EALIKCQPEG PFDLGGFSGG AMLSYEVSRQ LAAAGRVVSS LLLIDMCSPR PLGVEDTIEV GWKVYETIAS QDKLWNASSN TQQHLKAVFA CVAAYHPPPI TPAQRPKRTA IIWAKKGMVD RCSRDEKVMK FLADKGIPTE SYPGFMEDPK LGAVAWGLPH KSAADLGPNG WDKFLGETLC LSIDSDHLDM PMPGHVHLLQ AAMEESFKYF SEAN

References

Title : Enzymatic synthesis of resorcylic acid lactones by cooperation of fungal iterative polyketide synthases involved in hypothemycin biosynthesis - Zhou_2010_J.Am.Chem.Soc_132_4530
Author(s) : Zhou H , Qiao K , Gao Z , Meehan MJ , Li JW , Zhao X , Dorrestein PC , Vederas JC , Tang Y
Ref : Journal of the American Chemical Society , 132 :4530 , 2010
Abstract : Zhou_2010_J.Am.Chem.Soc_132_4530
ESTHER : Zhou_2010_J.Am.Chem.Soc_132_4530
PubMedSearch : Zhou_2010_J.Am.Chem.Soc_132_4530
PubMedID: 20222707
Gene_locus related to this paper: hypsb-hpm3

Title : Genes for the biosynthesis of the fungal polyketides hypothemycin from Hypomyces subiculosus and radicicol from Pochonia chlamydosporia - Reeves_2008_Appl.Environ.Microbiol_74_5121
Author(s) : Reeves CD , Hu Z , Reid R , Kealey JT
Ref : Applied Environmental Microbiology , 74 :5121 , 2008
Abstract : Reeves_2008_Appl.Environ.Microbiol_74_5121
ESTHER : Reeves_2008_Appl.Environ.Microbiol_74_5121
PubMedSearch : Reeves_2008_Appl.Environ.Microbiol_74_5121
PubMedID: 18567690
Gene_locus related to this paper: hypsb-hpm3 , metcm-rdc1

Title : Hypothemycin inhibits the proliferative response and modulates the production of cytokines during T cell activation - Camacho_1999_Immunopharmacology_44_255
Author(s) : Camacho R , Staruch MJ , Dasilva C , Koprak S , Sewell T , Salituro G , Dumont FJ
Ref : Immunopharmacology , 44 :255 , 1999
Abstract : Camacho_1999_Immunopharmacology_44_255
ESTHER : Camacho_1999_Immunopharmacology_44_255
PubMedSearch : Camacho_1999_Immunopharmacology_44_255
PubMedID: 10598882
Gene_locus related to this paper: hypsb-hpm3