luccu-E3aest7
Lucilia cuprina (and Lucilia sericata (Green bottle fly) (Phaenicia sericata)) alpha cluster carboxylesterase (OP resistance (LcaE7) E3
Comment
Relationship
Molecular evidence
No mutation
No kinetic
No disease
Database
Sequence
Peptide
MNFNVSLMEK LKWKIKCIEN KFLNYRLTTN ETVVAETEYG KVKGVKRLTV YDDSYYSFEG IPYAQPPVGE LRFKAPQRPT PWDGVRDCCN HKDKSVQVDF ITGKVCGSED CLYLSVYTNN LNPETKRPVL VYIHGGGFII GENHRDMYGP DYFIKKDVVL INIQYRLGAL GFLSLNSEDL NVPGNAGLKD QVMALRWIKN NCANFGGNPD NITVFGESAG AASTHYMMLT EQTRGLFHRG ILMSGNAICP WANTQCQHRA FTLAKLAGYK GEDNDKDVLE FLMKAKPQDL IKLEEKVLTL EERTNKVMFP FGPTVEPYQT ADCVLPKHPR EMVKTAWGNS IPTMMGNTSY EGLFFTSILK QMPMLVKELE TCVNFVPSEL ADAERTAPET LEMGAKIKKA HVTGETPTAD NFMDLCSHIY FWFPMHRLLQ LRFNHTSGTP VYLYRFDFDS EDLINPYRIM RSGRGVKGVS HADELTYFFW NQLAKRMPKE SREYKTIERM TGIWIQFATT GNPYSNEIEG MENVSWDPIK KSDEVYKCLN ISDELKMIDV PEMDKIKQWE SMFEKHRDLF
References
| Title : Overcoming insecticide resistance through computational inhibitor design - Correy_2019_Proc.Natl.Acad.Sci.U.S.A_116_21012 |
| Author(s) : Correy GJ , Zaidman D , Harmelin A , Carvalho S , Mabbitt PD , Calaora V , James PJ , Kotze AC , Jackson CJ , London N |
| Ref : Proc Natl Acad Sci U S A , 116 :21012 , 2019 |
| Abstract : Correy_2019_Proc.Natl.Acad.Sci.U.S.A_116_21012 |
| ESTHER : Correy_2019_Proc.Natl.Acad.Sci.U.S.A_116_21012 |
| PubMedSearch : Correy_2019_Proc.Natl.Acad.Sci.U.S.A_116_21012 |
| PubMedID: 31575743 |
| Gene_locus related to this paper: luccu-E3aest7 |
| Title : Conformational Disorganization within the Active Site of a Recently Evolved Organophosphate Hydrolase Limits Its Catalytic Efficiency - Mabbitt_2016_Biochemistry_55_1408 |
| Author(s) : Mabbitt PD , Correy GJ , Meirelles T , Fraser NJ , Coote ML , Jackson CJ |
| Ref : Biochemistry , 55 :1408 , 2016 |
| Abstract : Mabbitt_2016_Biochemistry_55_1408 |
| ESTHER : Mabbitt_2016_Biochemistry_55_1408 |
| PubMedSearch : Mabbitt_2016_Biochemistry_55_1408 |
| PubMedID: 26881849 |
| Gene_locus related to this paper: luccu-E3aest7 |
| Title : Evolution of Protein Quaternary Structure in Response to Selective Pressure for Increased Thermostability - Fraser_2016_J.Mol.Biol_428_2359 |
| Author(s) : Fraser NJ , Liu JW , Mabbitt PD , Correy GJ , Coppin CW , Lethier M , Perugini MA , Murphy JM , Oakeshott JG , Weik M , Jackson CJ |
| Ref : Journal of Molecular Biology , 428 :2359 , 2016 |
| Abstract : Fraser_2016_J.Mol.Biol_428_2359 |
| ESTHER : Fraser_2016_J.Mol.Biol_428_2359 |
| PubMedSearch : Fraser_2016_J.Mol.Biol_428_2359 |
| PubMedID: 27016206 |
| Gene_locus related to this paper: luccu-E3aest7 |
| Title : Mapping the Accessible Conformational Landscape of an Insect Carboxylesterase Using Conformational Ensemble Analysis and Kinetic Crystallography - Correy_2016_Structure_24_977 |
| Author(s) : Correy GJ , Carr PD , Meirelles T , Mabbitt PD , Fraser NJ , Weik M , Jackson CJ |
| Ref : Structure , 24 :977 , 2016 |
| Abstract : Correy_2016_Structure_24_977 |
| ESTHER : Correy_2016_Structure_24_977 |
| PubMedSearch : Correy_2016_Structure_24_977 |
| PubMedID: 27210287 |
| Gene_locus related to this paper: luccu-E3aest7 |
| Title : Structure and function of an insect alpha-carboxylesterase (alphaEsterase7) associated with insecticide resistance - Jackson_2013_Proc.Natl.Acad.Sci.U.S.A_110_10177 |
| Author(s) : Jackson CJ , Liu JW , Carr PD , Younus F , Coppin C , Meirelles T , Lethier M , Pandey G , Ollis DL , Russell RJ , Weik M , Oakeshott JG |
| Ref : Proc Natl Acad Sci U S A , 110 :10177 , 2013 |
| Abstract : Jackson_2013_Proc.Natl.Acad.Sci.U.S.A_110_10177 |
| ESTHER : Jackson_2013_Proc.Natl.Acad.Sci.U.S.A_110_10177 |
| PubMedSearch : Jackson_2013_Proc.Natl.Acad.Sci.U.S.A_110_10177 |
| PubMedID: 23733941 |
| Gene_locus related to this paper: luccu-E3aest7 |
| Title : Testing the evolvability of an insect carboxylesterase for the detoxification of synthetic pyrethroid insecticides - Coppin_2012_Insect.Biochem.Mol.Biol_42_343 |
| Author(s) : Coppin CW , Jackson CJ , Sutherland T , Hart PJ , Devonshire AL , Russell RJ , Oakeshott JG |
| Ref : Insect Biochemistry & Molecular Biology , 42 :343 , 2012 |
| Abstract : Coppin_2012_Insect.Biochem.Mol.Biol_42_343 |
| ESTHER : Coppin_2012_Insect.Biochem.Mol.Biol_42_343 |
| PubMedSearch : Coppin_2012_Insect.Biochem.Mol.Biol_42_343 |
| PubMedID: 22300675 |
| Gene_locus related to this paper: luccu-E3aest7 |
| Title : Hydrolysis of individual isomers of fluorogenic pyrethroid analogs by mutant carboxylesterases from Lucilia cuprina - Devonshire_2007_Insect.Biochem.Mol.Biol_37_891 |
| Author(s) : Devonshire AL , Heidari R , Huang HZ , Hammock BD , Russell RJ , Oakeshott JG |
| Ref : Insect Biochemistry & Molecular Biology , 37 :891 , 2007 |
| Abstract : Devonshire_2007_Insect.Biochem.Mol.Biol_37_891 |
| ESTHER : Devonshire_2007_Insect.Biochem.Mol.Biol_37_891 |
| PubMedSearch : Devonshire_2007_Insect.Biochem.Mol.Biol_37_891 |
| PubMedID: 17681228 |
| Gene_locus related to this paper: luccu-E3aest7 |
| Title : Multiple mutations and gene duplications conferring organophosphorus insecticide resistance have been selected at the Rop-1 locus of the sheep blowfly, Lucilia cuprina - Newcomb_2005_J.Mol.Evol_60_207 |
| Author(s) : Newcomb RD , Gleeson DM , Yong CG , Russell RJ , Oakeshott JG |
| Ref : Journal of Molecular Evolution , 60 :207 , 2005 |
| Abstract : Newcomb_2005_J.Mol.Evol_60_207 |
| ESTHER : Newcomb_2005_J.Mol.Evol_60_207 |
| PubMedSearch : Newcomb_2005_J.Mol.Evol_60_207 |
| PubMedID: 15785849 |
| Gene_locus related to this paper: luccu-E3aest7 |
| Title : Hydrolysis of pyrethroids by carboxylesterases from Lucilia cuprina and Drosophila melanogaster with active sites modified by in vitro mutagenesis - Heidari_2005_Insect.Biochem.Mol.Biol_35_597 |
| Author(s) : Heidari R , Devonshire AL , Campbell BE , Dorrian SJ , Oakeshott JG , Russell RJ |
| Ref : Insect Biochemistry & Molecular Biology , 35 :597 , 2005 |
| Abstract : Heidari_2005_Insect.Biochem.Mol.Biol_35_597 |
| ESTHER : Heidari_2005_Insect.Biochem.Mol.Biol_35_597 |
| PubMedSearch : Heidari_2005_Insect.Biochem.Mol.Biol_35_597 |
| PubMedID: 15857765 |
| Gene_locus related to this paper: drome-EST23aes07 , luccu-E3aest7 |
| Title : Hydrolysis of organophosphorus insecticides by in vitro modified carboxylesterase E3 from Lucilia cuprina - Heidari_2004_Insect.Biochem.Mol.Biol_34_353 |
| Author(s) : Heidari R , Devonshire AL , Campbell BE , Bell KL , Dorrian SJ , Oakeshott JG , Russell RJ |
| Ref : Insect Biochemistry & Molecular Biology , 34 :353 , 2004 |
| Abstract : Heidari_2004_Insect.Biochem.Mol.Biol_34_353 |
| ESTHER : Heidari_2004_Insect.Biochem.Mol.Biol_34_353 |
| PubMedSearch : Heidari_2004_Insect.Biochem.Mol.Biol_34_353 |
| PubMedID: 15041019 |
| Gene_locus related to this paper: luccu-E3aest7 |
| Title : Kinetic efficiency of mutant carboxylesterases implicated in organophosphate insecticide resistance - Devonshire_2003_Pestic.Biochem.Physiol_76_1 |
| Author(s) : Devonshire AL , Heidari R , Bell KL , Campbell PM , Campbell BE , Odgers WA , Oakeshott JG , Russell RJ |
| Ref : Pesticide Biochemistry and Physiology , 76 :1 , 2003 |
| Abstract : Devonshire_2003_Pestic.Biochem.Physiol_76_1 |
| ESTHER : Devonshire_2003_Pestic.Biochem.Physiol_76_1 |
| PubMedSearch : Devonshire_2003_Pestic.Biochem.Physiol_76_1 |
| PubMedID: |
| Gene_locus related to this paper: luccu-E3aest7 , musdo-EST23aes07 |
| Title : Two different amino acid substitutions in the ali-esterase, E3, confer alternative types of organophosphorus insecticide resistance in the sheep blowfly, Lucilia cuprina - Campbell_1998_Insect.Biochem.Mol.Biol_28_139 |
| Author(s) : Campbell PM , Newcomb RD , Russell RJ , Oakeshott JG |
| Ref : Insect Biochemistry & Molecular Biology , 28 :139 , 1998 |
| Abstract : Campbell_1998_Insect.Biochem.Mol.Biol_28_139 |
| ESTHER : Campbell_1998_Insect.Biochem.Mol.Biol_28_139 |
| PubMedSearch : Campbell_1998_Insect.Biochem.Mol.Biol_28_139 |
| PubMedID: |
| Gene_locus related to this paper: luccu-E3aest7 |
| Title : Biochemistry of esterases associated with organophosphate resistance in Lucilia cuprina with comparisons to putative orthologues in other Diptera - Campbell_1997_Biochem.Genet_35_17 |
| Author(s) : Campbell PM , Trott JF , Claudianos C , Smyth KA , Russell RJ , Oakeshott JG |
| Ref : Biochemical Genetics , 35 :17 , 1997 |
| Abstract : Campbell_1997_Biochem.Genet_35_17 |
| ESTHER : Campbell_1997_Biochem.Genet_35_17 |
| PubMedSearch : Campbell_1997_Biochem.Genet_35_17 |
| PubMedID: 9238516 |
| Gene_locus related to this paper: luccu-E3aest7 |
| Title : A single amino acid substitution converts a carboxylesterase to an organophosphorus hydrolase and confers insecticide resistance on a blowfly - Newcomb_1997_Proc.Natl.Acad.Sci.U.S.A_94_7464 |
| Author(s) : Newcomb RD , Campbell PM , Ollis DL , Cheah E , Russell RJ , Oakeshott JG |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 94 :7464 , 1997 |
| Abstract : Newcomb_1997_Proc.Natl.Acad.Sci.U.S.A_94_7464 |
| ESTHER : Newcomb_1997_Proc.Natl.Acad.Sci.U.S.A_94_7464 |
| PubMedSearch : Newcomb_1997_Proc.Natl.Acad.Sci.U.S.A_94_7464 |
| PubMedID: 9207114 |
| Gene_locus related to this paper: luccu-ACHE , luccu-E3aest7 |
| Title : Isolation of alpha cluster esterase genes associated with organophosphate resistance in Lucilia cuprina - Newcomb_1996_Insect.Mol.Biol_5_211 |
| Author(s) : Newcomb RD , East PD , Russell RJ , Oakeshott JG |
| Ref : Insect Molecular Biology , 5 :211 , 1996 |
| Abstract : Newcomb_1996_Insect.Mol.Biol_5_211 |
| ESTHER : Newcomb_1996_Insect.Mol.Biol_5_211 |
| PubMedSearch : Newcomb_1996_Insect.Mol.Biol_5_211 |
| PubMedID: 8799740 |
| Gene_locus related to this paper: luccu-E3aest7 |