Mus musculus (C57 Black/6X CBA) LAL mRNA for lysosomal acid lipase
Q8C2G7 from Okazaki differs by 4 aa || Q6PDR1 Q9Z0M5 some differences
MQLQGLVFVF TIGILLSRVP TGTVSAVDPE VNMNVTEIIM RWGYPGEEHS VLTGDGYILS IHRIPRGWKN HFGKGPRPVV YLQHGLLADS SNWVTNIDNS SLGFLLADRG FDVWMGNSRG NTWSLKHKTL SVSQDEFWAF SFDEMAKYDL PASINYILNK TGQEQIYYVG HSQGCTIGFI AFSQMPELAK KIKMFLVLAP VLSLNFASGP LLQLGRLPDP LLKDMFGQKQ FLPQSAMLKW LSIHVCTHVI MKELCANVFF LLCGFNEKNL NMSRVDVYTT HCPAELLVQN MLHWGQVFKY RKLQAFDWGS SEKNYFHYNQ SFPPSYNIKN MRLPTALWSG GRDWLADIND ITILLTQIPK LVYHKNIPEW DHLDFIWGLD APWKLYDEII SLMKKYQ
Title : Metabolic changes and propensity for inflammation, fibrosis, and cancer in livers of mice lacking lysosomal acid lipase - Bradic_2023_J.Lipid.Res__100427 |
Author(s) : Bradic I , Liesinger L , Kuentzel KB , Vujic N , Trauner M , Birner-Gruenberger R , Kratky D |
Ref : J Lipid Res , :100427 , 2023 |
Abstract : Bradic_2023_J.Lipid.Res__100427 |
ESTHER : Bradic_2023_J.Lipid.Res__100427 |
PubMedSearch : Bradic_2023_J.Lipid.Res__100427 |
PubMedID: 37595802 |
Gene_locus related to this paper: human-LIPA , mouse-1llip |
Title : JLR-D-23-00401-R1 Dissecting cell type-specific impact in lysosomal acid lipase deficiency-associated disorders - |
Author(s) : Westerterp M , Li F , Zhang H |
Ref : J Lipid Res , :100474 , 2023 |
PubMedID: 37972729 |
Gene_locus related to this paper: human-LIPA , mouse-1llip |
Title : LAL deficiency induced myeloid-derived suppressor cells as targets and biomarkers for lung cancer - Zhao_2023_J.Immunother.Cancer_11_ |
Author(s) : Zhao T , Liu S , Hanna NH , Jalal S , Ding X , Wan J , Yan C , Du H |
Ref : J Immunother Cancer , 11 : , 2023 |
Abstract : Zhao_2023_J.Immunother.Cancer_11_ |
ESTHER : Zhao_2023_J.Immunother.Cancer_11_ |
PubMedSearch : Zhao_2023_J.Immunother.Cancer_11_ |
PubMedID: 36914206 |
Gene_locus related to this paper: mouse-1llip |
Title : Loss of lysosomal acid lipase results in mitochondrial dysfunction and fiber switch in skeletal muscles of mice - Akhmetshina_2023_Mol.Metab__101869 |
Author(s) : Akhmetshina A , Bianco V , Bradic I , Korbelius M , Pirchheim A , Kuentzel KB , Eichmann TO , Hinteregger H , Kolb D , Habisch H , Liesinger L , Madl T , Sattler W , Radovic B , Sedej S , Birner-Gruenberger R , Vujic N , Kratky D |
Ref : Mol Metab , :101869 , 2023 |
Abstract : Akhmetshina_2023_Mol.Metab__101869 |
ESTHER : Akhmetshina_2023_Mol.Metab__101869 |
PubMedSearch : Akhmetshina_2023_Mol.Metab__101869 |
PubMedID: 38160938 |
Gene_locus related to this paper: human-LIPA , mouse-1llip |
Title : Therapeutic efficacy of rscAAVrh74.miniCMV.LIPA gene therapy in a mouse model of lysosomal acid lipase deficiency - Lam_2022_Mol.Ther.Methods.Clin.Dev_26_413 |
Author(s) : Lam P , Ashbrook A , Zygmunt DA , Yan C , Du H , Martin PT |
Ref : Mol Ther Methods Clin Dev , 26 :413 , 2022 |
Abstract : Lam_2022_Mol.Ther.Methods.Clin.Dev_26_413 |
ESTHER : Lam_2022_Mol.Ther.Methods.Clin.Dev_26_413 |
PubMedSearch : Lam_2022_Mol.Ther.Methods.Clin.Dev_26_413 |
PubMedID: 36092360 |
Gene_locus related to this paper: mouse-1llip , human-LIPA |
Title : Loss of Function of Lysosomal Acid Lipase (LAL) Profoundly Impacts Osteoblastogenesis and Increases Fracture Risk in Humans - Helderman_2021_Bone__115946 |
Author(s) : Helderman RC , Whitney DG , Duta-Mare M , Akhmetshina A , Vujic N , Jayapalan S , Nyman JS , Misra BB , Rosen CJ , Czech MP , Kratky D , Rendina-Ruedy E |
Ref : Bone , :115946 , 2021 |
Abstract : Helderman_2021_Bone__115946 |
ESTHER : Helderman_2021_Bone__115946 |
PubMedSearch : Helderman_2021_Bone__115946 |
PubMedID: 33838322 |
Gene_locus related to this paper: human-LIPA , mouse-1llip |
Title : Hepatocyte-specific lysosomal acid lipase deficiency protects mice from diet-induced obesity but promotes hepatic inflammation - Leopold_2019_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1864_500 |
Author(s) : Leopold C , Duta-Mare M , Sachdev V , Goeritzer M , Maresch LK , Kolb D , Reicher H , Wagner B , Stojakovic T , Ruelicke T , Haemmerle G , Hoefler G , Sattler W , Kratky D |
Ref : Biochimica & Biophysica Acta Molecular & Cellular Biology Lipids , 1864 :500 , 2019 |
Abstract : Leopold_2019_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1864_500 |
ESTHER : Leopold_2019_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1864_500 |
PubMedSearch : Leopold_2019_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1864_500 |
PubMedID: 30639734 |
Gene_locus related to this paper: mouse-1llip |
Title : Lysosomal acid lipase regulates fatty acid channeling in brown adipose tissue to maintain thermogenesis - Duta-Mare_2018_Biochim.Biophys.Acta_1863_467 |
Author(s) : Duta-Mare M , Sachdev V , Leopold C , Kolb D , Vujic N , Korbelius M , Hofer DC , Xia W , Huber K , Auer M , Gottschalk B , Magnes C , Graier WF , Prokesch A , Radovic B , Bogner-Strauss JG , Kratky D |
Ref : Biochimica & Biophysica Acta , 1863 :467 , 2018 |
Abstract : Duta-Mare_2018_Biochim.Biophys.Acta_1863_467 |
ESTHER : Duta-Mare_2018_Biochim.Biophys.Acta_1863_467 |
PubMedSearch : Duta-Mare_2018_Biochim.Biophys.Acta_1863_467 |
PubMedID: 29374543 |
Gene_locus related to this paper: mouse-1llip |
Title : Lysosomal lipid hydrolysis provides substrates for lipid mediator synthesis in murine macrophages - Schlager_2017_Oncotarget_8_40037 |
Author(s) : Schlager S , Vujic N , Korbelius M , Duta-Mare M , Dorow J , Leopold C , Rainer S , Wegscheider M , Reicher H , Ceglarek U , Sattler W , Radovic B , Kratky D |
Ref : Oncotarget , 8 :40037 , 2017 |
Abstract : Schlager_2017_Oncotarget_8_40037 |
ESTHER : Schlager_2017_Oncotarget_8_40037 |
PubMedSearch : Schlager_2017_Oncotarget_8_40037 |
PubMedID: 28402950 |
Gene_locus related to this paper: mouse-1llip |
Title : Endothelial Rab7 GTPase mediates tumor growth and metastasis in lysosomal acid lipase-deficient mice - Zhao_2017_J.Biol.Chem_292_19198 |
Author(s) : Zhao T , Ding X , Yan C , Du H |
Ref : Journal of Biological Chemistry , 292 :19198 , 2017 |
Abstract : Zhao_2017_J.Biol.Chem_292_19198 |
ESTHER : Zhao_2017_J.Biol.Chem_292_19198 |
PubMedSearch : Zhao_2017_J.Biol.Chem_292_19198 |
PubMedID: 28924047 |
Gene_locus related to this paper: mouse-1llip |
Title : Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover - Grumet_2016_J.Biol.Chem_291_17977 |
Author(s) : Grumet L , Eichmann TO , Taschler U , Zierler KA , Leopold C , Moustafa T , Radovic B , Romauch M , Yan C , Du H , Haemmerle G , Zechner R , Fickert P , Kratky D , Zimmermann R , Lass A |
Ref : Journal of Biological Chemistry , 291 :17977 , 2016 |
Abstract : Grumet_2016_J.Biol.Chem_291_17977 |
ESTHER : Grumet_2016_J.Biol.Chem_291_17977 |
PubMedSearch : Grumet_2016_J.Biol.Chem_291_17977 |
PubMedID: 27354281 |
Gene_locus related to this paper: human-LIPA , mouse-1llip |
Title : Hepatocyte-Specific Expression of Human Lysosome Acid Lipase Corrects Liver Inflammation and Tumor Metastasis in lal(-\/-) Mice - Du_2015_Am.J.Pathol_185_2379 |
Author(s) : Du H , Zhao T , Ding X , Yan C |
Ref : American Journal of Pathology , 185 :2379 , 2015 |
Abstract : Du_2015_Am.J.Pathol_185_2379 |
ESTHER : Du_2015_Am.J.Pathol_185_2379 |
PubMedSearch : Du_2015_Am.J.Pathol_185_2379 |
PubMedID: 26212911 |
Gene_locus related to this paper: mouse-1llip |
Title : Reversal of advanced disease in lysosomal acid lipase deficient mice: a model for lysosomal acid lipase deficiency disease - Sun_2014_Mol.Genet.Metab_112_229 |
Author(s) : Sun Y , Xu YH , Du H , Quinn B , Liou B , Stanton L , Inskeep V , Ran H , Jakubowitz P , Grilliot N , Grabowski GA |
Ref : Mol Genet Metab , 112 :229 , 2014 |
Abstract : Sun_2014_Mol.Genet.Metab_112_229 |
ESTHER : Sun_2014_Mol.Genet.Metab_112_229 |
PubMedSearch : Sun_2014_Mol.Genet.Metab_112_229 |
PubMedID: 24837159 |
Gene_locus related to this paper: mouse-1llip |
Title : Quantitative role of LAL, NPC2, and NPC1 in lysosomal cholesterol processing defined by genetic and pharmacological manipulations - Ramirez_2011_J.Lipid.Res_52_688 |
Author(s) : Ramirez CM , Liu B , Aqul A , Taylor AM , Repa JJ , Turley SD , Dietschy JM |
Ref : J Lipid Res , 52 :688 , 2011 |
Abstract : Ramirez_2011_J.Lipid.Res_52_688 |
ESTHER : Ramirez_2011_J.Lipid.Res_52_688 |
PubMedSearch : Ramirez_2011_J.Lipid.Res_52_688 |
PubMedID: 21289032 |
Gene_locus related to this paper: mouse-1llip |
Title : Critical roles of lysosomal acid lipase in myelopoiesis - Qu_2010_Am.J.Pathol_176_2394 |
Author(s) : Qu P , Shelley WC , Yoder MC , Wu L , Du H , Yan C |
Ref : American Journal of Pathology , 176 :2394 , 2010 |
Abstract : Qu_2010_Am.J.Pathol_176_2394 |
ESTHER : Qu_2010_Am.J.Pathol_176_2394 |
PubMedSearch : Qu_2010_Am.J.Pathol_176_2394 |
PubMedID: 20348241 |
Gene_locus related to this paper: mouse-1llip |
Title : Critical roles of lysosomal acid lipase in T cell development and function - Qu_2009_Am.J.Pathol_174_944 |
Author(s) : Qu P , Du H , Wilkes DS , Yan C |
Ref : American Journal of Pathology , 174 :944 , 2009 |
Abstract : Qu_2009_Am.J.Pathol_174_944 |
ESTHER : Qu_2009_Am.J.Pathol_174_944 |
PubMedSearch : Qu_2009_Am.J.Pathol_174_944 |
PubMedID: 19179613 |
Gene_locus related to this paper: mouse-1llip |
Title : Wolman disease\/cholesteryl ester storage disease: efficacy of plant-produced human lysosomal acid lipase in mice - Du_2008_J.Lipid.Res_49_1646 |
Author(s) : Du H , Cameron TL , Garger SJ , Pogue GP , Hamm LA , White E , Hanley KM , Grabowski GA |
Ref : J Lipid Res , 49 :1646 , 2008 |
Abstract : Du_2008_J.Lipid.Res_49_1646 |
ESTHER : Du_2008_J.Lipid.Res_49_1646 |
PubMedSearch : Du_2008_J.Lipid.Res_49_1646 |
PubMedID: 18413899 |
Gene_locus related to this paper: mouse-1llip |
Title : Lysosomal acid lipase over-expression disrupts lamellar body genesis and alveolar structure in the lung - Li_2007_Int.J.Exp.Pathol_88_427 |
Author(s) : Li Y , Qin Y , Li H , Wu R , Yan C , Du H |
Ref : International Journal of Experimental Pathology , 88 :427 , 2007 |
Abstract : Li_2007_Int.J.Exp.Pathol_88_427 |
ESTHER : Li_2007_Int.J.Exp.Pathol_88_427 |
PubMedSearch : Li_2007_Int.J.Exp.Pathol_88_427 |
PubMedID: 18039279 |
Gene_locus related to this paper: mouse-1llip |
Title : Neutral lipids and peroxisome proliferator-activated receptor-{gamma} control pulmonary gene expression and inflammation-triggered pathogenesis in lysosomal acid lipase knockout mice - Lian_2005_Am.J.Pathol_167_813 |
Author(s) : Lian X , Yan C , Qin Y , Knox L , Li T , Du H |
Ref : American Journal of Pathology , 167 :813 , 2005 |
Abstract : Lian_2005_Am.J.Pathol_167_813 |
ESTHER : Lian_2005_Am.J.Pathol_167_813 |
PubMedSearch : Lian_2005_Am.J.Pathol_167_813 |
PubMedID: 16127159 |
Gene_locus related to this paper: mouse-1llip |
Title : Lysosomal acid lipase deficiency causes respiratory inflammation and destruction in the lung - Lian_2004_Am.J.Physiol.Lung.Cell.Mol.Physiol_286_L801 |
Author(s) : Lian X , Yan C , Yang L , Xu Y , Du H |
Ref : American Journal of Physiology Lung Cell Mol Physiol , 286 :L801 , 2004 |
Abstract : Lian_2004_Am.J.Physiol.Lung.Cell.Mol.Physiol_286_L801 |
ESTHER : Lian_2004_Am.J.Physiol.Lung.Cell.Mol.Physiol_286_L801 |
PubMedSearch : Lian_2004_Am.J.Physiol.Lung.Cell.Mol.Physiol_286_L801 |
PubMedID: 14644759 |
Gene_locus related to this paper: mouse-1llip |
Title : Lysosomal Acid lipase deficiency: correction of lipid storage by adenovirus-mediated gene transfer in mice - Du_2002_Hum.Gene.Ther_13_1361 |
Author(s) : Du H , Heur M , Witte DP , Ameis D , Grabowski GA |
Ref : Hum Gene Therapy , 13 :1361 , 2002 |
Abstract : Du_2002_Hum.Gene.Ther_13_1361 |
ESTHER : Du_2002_Hum.Gene.Ther_13_1361 |
PubMedSearch : Du_2002_Hum.Gene.Ther_13_1361 |
PubMedID: 12162818 |
Gene_locus related to this paper: mouse-1llip |
Title : Enzyme therapy for lysosomal acid lipase deficiency in the mouse - Du_2001_Hum.Mol.Genet_10_1639 |
Author(s) : Du H , Schiavi S , Levine M , Mishra J , Heur M , Grabowski GA |
Ref : Hum Mol Genet , 10 :1639 , 2001 |
Abstract : Du_2001_Hum.Mol.Genet_10_1639 |
ESTHER : Du_2001_Hum.Mol.Genet_10_1639 |
PubMedSearch : Du_2001_Hum.Mol.Genet_10_1639 |
PubMedID: 11487567 |
Gene_locus related to this paper: mouse-1llip |
Title : Targeted disruption of the mouse lysosomal acid lipase gene: long-term survival with massive cholesteryl ester and triglyceride storage - Du_1998_Hum.Mol.Genet_7_1347 |
Author(s) : Du H , Duanmu M , Witte D , Grabowski GA |
Ref : Hum Mol Genet , 7 :1347 , 1998 |
Abstract : Du_1998_Hum.Mol.Genet_7_1347 |
ESTHER : Du_1998_Hum.Mol.Genet_7_1347 |
PubMedSearch : Du_1998_Hum.Mol.Genet_7_1347 |
PubMedID: 9700186 |
Gene_locus related to this paper: mouse-1llip |
Title : Tissue and cellular specific expression of murine lysosomal acid lipase mRNA and protein - Du_1996_J.Lipid.Res_37_937 |
Author(s) : Du H , Witte DP , Grabowski GA |
Ref : J Lipid Res , 37 :937 , 1996 |
Abstract : Du_1996_J.Lipid.Res_37_937 |
ESTHER : Du_1996_J.Lipid.Res_37_937 |
PubMedSearch : Du_1996_J.Lipid.Res_37_937 |
PubMedID: 8725147 |
Gene_locus related to this paper: human-LIPA , mouse-1llip |