Mus musculus (Mouse)acyl-CoA thioesterase 6 (EC 3.1.2.2). Weakly similar to peroxisomal acyl-coenzyme A thioester hydrolase2
The mouse ACOT gene cluster comprises six genes with localizations in cytosol (ACOT1), mitochondria (ACOT2), and peroxisomes (ACOT3-6). The corresponding human gene cluster contains only three genes (ACOT1, ACOT2, and ACOT4) coding for full-length thioesterase proteins only ACOT4 is peroxisomal
MAATLSVEPA GRSCWDEPLS IAVRGLAPEQ PVTLRSVLRD EKGMLFRAHA RYRADSHGEL DLARTPALGG SFSGLEPMGL LWAMEPDRPF WRLIKRDVQI PFVVELEVLD GHEPDGGQRL ARAVHERHFM APGVRRVPVR EGRVRATLFL PPGKGQFPGI IDLYGSIGGL CEHRASLLAG HGFAVLALAY FQFEDLPENL SDVRLEYFEE ALALMLRHPQ VKGPNIGLIG VSKGADLCLS MAAFLKDNIT ATVLINACVA NTLVPLYYKD LFVPELGCDQ TKNKSGLMDL RDMWNNPLEE PNHQSLIPLE KAQGPFLFLV GMDDHNWKSD VYARIACERL QAHGKDRPQI IYYPETGHCI EPPYFPPPIA TVHFVLGEAV FNGGKPRAQS RAQLDAWQRI QTFFQKYLNG EKPARHSKL
Title : Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs - Hunt_2006_FASEB.J_20_1855 |
Author(s) : Hunt MC , Rautanen A , Westin MA , Svensson LT , Alexson SE |
Ref : FASEB Journal , 20 :1855 , 2006 |
Abstract : Hunt_2006_FASEB.J_20_1855 |
ESTHER : Hunt_2006_FASEB.J_20_1855 |
PubMedSearch : Hunt_2006_FASEB.J_20_1855 |
PubMedID: 16940157 |
Gene_locus related to this paper: human-ACOT1 , human-ACOT2 , human-ACOT4 , human-ACOT6 , mouse-acot1 , mouse-acot2 , mouse-acot3 , mouse-acot4 , mouse-acot5 , mouse-ACOT6 |