neime-r0tza2
Neisseria meningitidis. Capsule biosynthesis protein sacC CsaC
Comment
Capsular polysaccharide (CPS) is the major virulence factor of Nessaria meningentidis and serves for raising potent vaccines. The repeating unit [->6)-alpha-D-ManNAc-(1->OPO3-->] is O-acetylated at position C3 and C4 in Nm serogroup A (NmA-CPS). O-acetyltransferase CsaC (MynC) is responsible for the acetylation. Other strains: Neisseria meningitidis (NM606\; NM3642\; 65012\; 2001212\; 2007056\; 63041\; 96024\; 2003022\; 2004090\; 68094\; 69155\; 64182\; 61103\; 98005\; 2004085\;\; 70012\; NM604\;\; 69096\; 96023\; 88050\; 63049\; 96060\; 70030\; 97018\; NM3652\; 97008\; serogroup A \/ serotype 4\; 63006\; 63023\; 2000063\; 94018\; 75689\; 75643\; 2000080\; 69176\; NM607\; 61106\; 2002007\; 97020\; 70082\; serogroup A\; 70021\; 69100\; 65014\; 69166)
Relationship
Database
Sequence
Peptide
MLSNLKTGNN ILGLPEFELN GCRFLYKKGI EKTIITFSAF PPKDIAQKYN YIKDFLSSNY TFLAFLDTKY PEDDARGTYY ITNELDNGYL QTIHCIIQLL SNTNQEDTYL LGSSKGGVGA LLLGLTYNYP NIIINAPQAK LADYIKTRSK TILSYMLGTS KRFQDINYDY INDFLLSKIK TCDSSLKWNI HITCGKDDSY HLNELEILKN EFNIKAITIK TKLISGGHDN EAIAHYREYF KTIIQNI
References
| Title : Structural and mechanistic basis of capsule O-acetylation in Neisseria meningitidis serogroup A - Fiebig_2020_Nat.Commun_11_4723 |
| Author(s) : Fiebig T , Cramer JT , Bethe A , Baruch P , Curth U , Fuhring JI , Buettner FFR , Vogel U , Schubert M , Fedorov R , Muhlenhoff M |
| Ref : Nat Commun , 11 :4723 , 2020 |
| Abstract : Fiebig_2020_Nat.Commun_11_4723 |
| ESTHER : Fiebig_2020_Nat.Commun_11_4723 |
| PubMedSearch : Fiebig_2020_Nat.Commun_11_4723 |
| PubMedID: 32948778 |
| Gene_locus related to this paper: neime-r0tza2 |
| Title : Complete Genome Sequence of Neisseria meningitidis Serogroup A Strain NMA510612, Isolated from a Patient with Bacterial Meningitis in China - Zhang_2014_Genome.Announc_2_e00360 |
| Author(s) : Zhang Y , Yang J , Xu L , Zhu Y , Liu B , Shao Z , Zhang X , Jin Q |
| Ref : Genome Announc , 2 :e00360 , 2014 |
| Abstract : Zhang_2014_Genome.Announc_2_e00360 |
| ESTHER : Zhang_2014_Genome.Announc_2_e00360 |
| PubMedSearch : Zhang_2014_Genome.Announc_2_e00360 |
| PubMedID: 24812217 |
| Gene_locus related to this paper: neime-r0tza2 |
| Title : Whole-genome sequence of the transformable Neisseria meningitidis serogroup A strain WUE2594 - Schoen_2011_J.Bacteriol_193_2064 |
| Author(s) : Schoen C , Weber-Lehmann J , Blom J , Joseph B , Goesmann A , Strittmatter A , Frosch M |
| Ref : Journal of Bacteriology , 193 :2064 , 2011 |
| Abstract : Schoen_2011_J.Bacteriol_193_2064 |
| ESTHER : Schoen_2011_J.Bacteriol_193_2064 |
| PubMedSearch : Schoen_2011_J.Bacteriol_193_2064 |
| PubMedID: 21296965 |
| Gene_locus related to this paper: neigo-pip , neima-metx , neime-ESD , neime-NMB0276 , neime-NMB1877 , neime-r0tza2 |
| Title : Genetic study of capsular switching between Neisseria meningitidis sequence type 7 serogroup A and C strains - Wang_2010_Infect.Immun_78_3883 |
| Author(s) : Wang Q , Shao Z , Wang X , Gao Y , Li M , Xu L , Xu J , Wang L |
| Ref : Infect Immun , 78 :3883 , 2010 |
| Abstract : Wang_2010_Infect.Immun_78_3883 |
| ESTHER : Wang_2010_Infect.Immun_78_3883 |
| PubMedSearch : Wang_2010_Infect.Immun_78_3883 |
| PubMedID: 20624905 |
| Gene_locus related to this paper: neime-r0tza2 |
| Title : Complete DNA sequence of a serogroup A strain of Neisseria meningitidis Z2491 - Parkhill_2000_Nature_404_502 |
| Author(s) : Parkhill J , Achtman M , James KD , Bentley SD , Churcher C , Klee SR , Morelli G , Basham D , Brown D , Chillingworth T , Davies RM , Davis P , Devlin K , Feltwell T , Hamlin N , Holroyd S , Jagels K , Leather S , Moule S , Mungall K , Quail MA , Rajandream MA , Rutherford KM , Simmonds M , Skelton J , Whitehead S , Spratt BG , Barrell BG |
| Ref : Nature , 404 :502 , 2000 |
| Abstract : Parkhill_2000_Nature_404_502 |
| ESTHER : Parkhill_2000_Nature_404_502 |
| PubMedSearch : Parkhill_2000_Nature_404_502 |
| PubMedID: 10761919 |
| Gene_locus related to this paper: neima-metx , neimb-q9k0t9 , neime-ESD , neime-NMA2216 , neime-NMB0276 , neime-NMB1877 , neimf-a1kta9 , neime-r0tza2 |
| Title : Characterization of the gene cassette required for biosynthesis of the (alpha1-->\;6)-linked N-acetyl-D-mannosamine-1-phosphate capsule of serogroup A Neisseria meningitidis - Swartley_1998_J.Bacteriol_180_1533 |
| Author(s) : Swartley JS , Liu LJ , Miller YK , Martin LE , Edupuganti S , Stephens DS |
| Ref : Journal of Bacteriology , 180 :1533 , 1998 |
| Abstract : Swartley_1998_J.Bacteriol_180_1533 |
| ESTHER : Swartley_1998_J.Bacteriol_180_1533 |
| PubMedSearch : Swartley_1998_J.Bacteriol_180_1533 |
| PubMedID: 9515923 |
| Gene_locus related to this paper: neime-r0tza2 |