pseae-PA2934
Pseudomonas aeruginosa (strains PA01, PA2934 LESB58; 2192; UCBPP-PA14; C3719) the CFTR inhibitory factor Cif an epoxide hydrolase virulence factor
Comment
Relationship
Molecular evidence
No mutation
No kinetic
No disease
Sequence
Peptide
MILDRLCRGL LAGIALTFSL GGFAAEEFPV PNGFESAYRE VDGVKLHYVK GGQGPLVMLV HGFGQTWYEW HQLMPELAKR FTVIAPDLPG LGQSEPPKTG YSGEQVAVYL HKLARQFSPD RPFDLVAHDI GIWNTYPMVV KNQADIARLV YMEAPIPDAR IYRFPAFTAQ GESLVWHFSF FAADDRLAET LIAGKERFFL EHFIKSHSSN TEVFSERLLD LYARSYAKPH SLNASFEYYR ALNESVRQNA ELAKTRLQMP TMTLAGGGHG GMGTFQLEQM KAYADDVEGH VLPGCGHWLP EECAAPMNRL VIDFLSRGR
References
| Title : Molecular basis for the transcriptional regulation of an epoxide-based virulence circuit in Pseudomonas aeruginosa - He_2024_bioRxiv__ |
| Author(s) : He S , Taher NM , Hvorecny KL , Ragusa MJ , Bahl CD , Hickman AB , Dyda F , Madden DR |
| Ref : Biorxiv , : , 2024 |
| Abstract : He_2024_bioRxiv__ |
| ESTHER : He_2024_bioRxiv__ |
| PubMedSearch : He_2024_bioRxiv__ |
| PubMedID: 38293063 |
| Gene_locus related to this paper: pseae-PA2934 |
| Title : Pseudomonas aeruginosa sabotages the generation of host proresolving lipid mediators - Flitter_2017_Proc.Natl.Acad.Sci.U.S.A_114_136 |
| Author(s) : Flitter BA , Hvorecny KL , Ono E , Eddens T , Yang J , Kwak DH , Bahl CD , Hampton TH , Morisseau C , Hammock BD , Liu X , Lee JS , Kolls JK , Levy BD , Madden DR , Bomberger JM |
| Ref : Proc Natl Acad Sci U S A , 114 :136 , 2017 |
| Abstract : Flitter_2017_Proc.Natl.Acad.Sci.U.S.A_114_136 |
| ESTHER : Flitter_2017_Proc.Natl.Acad.Sci.U.S.A_114_136 |
| PubMedSearch : Flitter_2017_Proc.Natl.Acad.Sci.U.S.A_114_136 |
| PubMedID: 27980032 |
| Gene_locus related to this paper: pseae-PA2934 |
| Title : Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase - Hvorecny_2017_Structure_25_697 |
| Author(s) : Hvorecny KL , Bahl CD , Kitamura S , Lee KSS , Hammock BD , Morisseau C , Madden DR |
| Ref : Structure , 25 :697 , 2017 |
| Abstract : Hvorecny_2017_Structure_25_697 |
| ESTHER : Hvorecny_2017_Structure_25_697 |
| PubMedSearch : Hvorecny_2017_Structure_25_697 |
| PubMedID: 28392259 |
| Gene_locus related to this paper: pseae-PA2934 |
| Title : Visualizing the Mechanism of Epoxide Hydrolysis by the Bacterial Virulence Enzyme Cif - Bahl_2016_Biochemistry_55_788 |
| Author(s) : Bahl CD , Hvorecny KL , Morisseau C , Gerber SA , Madden DR |
| Ref : Biochemistry , 55 :788 , 2016 |
| Abstract : Bahl_2016_Biochemistry_55_788 |
| ESTHER : Bahl_2016_Biochemistry_55_788 |
| PubMedSearch : Bahl_2016_Biochemistry_55_788 |
| PubMedID: 26752215 |
| Gene_locus related to this paper: pseae-PA2934 |
| Title : Rational Design of Potent and Selective Inhibitors of an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa - Kitamura_2016_J.Med.Chem_59_4790 |
| Author(s) : Kitamura S , Hvorecny KL , Niu J , Hammock BD , Madden DR , Morisseau C |
| Ref : Journal of Medicinal Chemistry , 59 :4790 , 2016 |
| Abstract : Kitamura_2016_J.Med.Chem_59_4790 |
| ESTHER : Kitamura_2016_J.Med.Chem_59_4790 |
| PubMedSearch : Kitamura_2016_J.Med.Chem_59_4790 |
| PubMedID: 27120257 |
| Gene_locus related to this paper: pseae-PA2934 |
| Title : Inhibiting an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa Protects CFTR - Bahl_2015_Angew.Chem.Int.Ed.Engl_54_9881 |
| Author(s) : Bahl CD , Hvorecny KL , Bomberger JM , Stanton BA , Hammock BD , Morisseau C , Madden DR |
| Ref : Angew Chem Int Ed Engl , 54 :9881 , 2015 |
| Abstract : Bahl_2015_Angew.Chem.Int.Ed.Engl_54_9881 |
| ESTHER : Bahl_2015_Angew.Chem.Int.Ed.Engl_54_9881 |
| PubMedSearch : Bahl_2015_Angew.Chem.Int.Ed.Engl_54_9881 |
| PubMedID: 26136396 |
| Gene_locus related to this paper: pseae-PA2934 |
| Title : Signature motifs identify an acinetobacter cif virulence factor with epoxide hydrolase activity - Bahl_2014_J.Biol.Chem_289_7460 |
| Author(s) : Bahl CD , Hvorecny KL , Bridges AA , Ballok AE , Bomberger JM , Cady KC , O'Toole GA , Madden DR |
| Ref : Journal of Biological Chemistry , 289 :7460 , 2014 |
| Abstract : Bahl_2014_J.Biol.Chem_289_7460 |
| ESTHER : Bahl_2014_J.Biol.Chem_289_7460 |
| PubMedSearch : Bahl_2014_J.Biol.Chem_289_7460 |
| PubMedID: 24474692 |
| Gene_locus related to this paper: pseae-PA2934 , 9gamm-d0bwk6 |
| Title : Pseudomonas aeruginosa Cif Protein Enhances the Ubiquitination and Proteasomal Degradation of the Transporter Associated with Antigen Processing (TAP) and Reduces Major Histocompatibility Complex (MHC) Class I Antigen Presentation - Bomberger_2014_J.Biol.Chem_289_152 |
| Author(s) : Bomberger JM , Ely KH , Bangia N , Ye S , Green KA , Green WR , Enelow RI , Stanton BA |
| Ref : Journal of Biological Chemistry , 289 :152 , 2014 |
| Abstract : Bomberger_2014_J.Biol.Chem_289_152 |
| ESTHER : Bomberger_2014_J.Biol.Chem_289_152 |
| PubMedSearch : Bomberger_2014_J.Biol.Chem_289_152 |
| PubMedID: 24247241 |
| Gene_locus related to this paper: pseae-PA2934 |
| Title : Epoxide-mediated CifR repression of cif gene expression utilizes two binding sites in Pseudomonas aeruginosa - Ballok_2012_J.Bacteriol_194_5315 |
| Author(s) : Ballok AE , Bahl CD , Dolben EL , Lindsay AK , St Laurent JD , Hogan DA , Madden DR , O'Toole GA |
| Ref : Journal of Bacteriology , 194 :5315 , 2012 |
| Abstract : Ballok_2012_J.Bacteriol_194_5315 |
| ESTHER : Ballok_2012_J.Bacteriol_194_5315 |
| PubMedSearch : Ballok_2012_J.Bacteriol_194_5315 |
| PubMedID: 22843844 |
| Gene_locus related to this paper: pseae-PA2934 |
| Title : Pseudomonas aeruginosa Cif defines a distinct class of alpha\/beta epoxide hydrolases utilizing a His\/Tyr ring-opening pair - Bahl_2012_Protein.Pept.Lett_19_186 |
| Author(s) : Bahl CD , Madden DR |
| Ref : Protein Pept Lett , 19 :186 , 2012 |
| Abstract : Bahl_2012_Protein.Pept.Lett_19_186 |
| ESTHER : Bahl_2012_Protein.Pept.Lett_19_186 |
| PubMedSearch : Bahl_2012_Protein.Pept.Lett_19_186 |
| PubMedID: 21933119 |
| Gene_locus related to this paper: pseae-PA2934 |
| Title : A Pseudomonas aeruginosa toxin that hijacks the host ubiquitin proteolytic system - Bomberger_2011_PLoS.Pathog_7_e1001325 |
| Author(s) : Bomberger JM , Ye S , Maceachran DP , Koeppen K , Barnaby RL , O'Toole GA , Stanton BA |
| Ref : PLoS Pathog , 7 :e1001325 , 2011 |
| Abstract : Bomberger_2011_PLoS.Pathog_7_e1001325 |
| ESTHER : Bomberger_2011_PLoS.Pathog_7_e1001325 |
| PubMedSearch : Bomberger_2011_PLoS.Pathog_7_e1001325 |
| PubMedID: 21455491 |
| Gene_locus related to this paper: pseae-PA2934 |
| Title : Crystal structure of the CFTR inhibitory factor Cif reveals novel active-site features of an epoxide hydrolase virulence factor. - Bahl_2010_J.Bacteriol_192_1785 |
| Author(s) : Bahl CD , Morisseau C , Bomberger JM , Stanton BA , Hammock BD , O'Toole GA , Madden DR |
| Ref : Journal of Bacteriology , 192 :1785 , 2010 |
| Abstract : Bahl_2010_J.Bacteriol_192_1785 |
| ESTHER : Bahl_2010_J.Bacteriol_192_1785 |
| PubMedSearch : Bahl_2010_J.Bacteriol_192_1785 |
| PubMedID: 20118260 |
| Gene_locus related to this paper: pseae-PA2934 |
| Title : Purification, crystallization and preliminary X-ray diffraction analysis of Cif, a virulence factor secreted by Pseudomonas aeruginosa - Bahl_2010_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_66_26 |
| Author(s) : Bahl CD , Maceachran DP , O'Toole GA , Madden DR |
| Ref : Acta Crystallographica Sect F Struct Biol Cryst Commun , 66 :26 , 2010 |
| Abstract : Bahl_2010_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_66_26 |
| ESTHER : Bahl_2010_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_66_26 |
| PubMedSearch : Bahl_2010_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_66_26 |
| PubMedID: 20057063 |
| Gene_locus related to this paper: pseae-PA2934 |
| Title : Chemotoxicity of doxorubicin and surface expression of P-glycoprotein (MDR1) is regulated by the Pseudomonas aeruginosa toxin Cif - Ye_2008_Am.J.Physiol.Cell.Physiol_295_C807 |
| Author(s) : Ye S , Maceachran DP , Hamilton JW , O'Toole GA , Stanton BA |
| Ref : American Journal of Physiology Cell Physiol , 295 :C807 , 2008 |
| Abstract : Ye_2008_Am.J.Physiol.Cell.Physiol_295_C807 |
| ESTHER : Ye_2008_Am.J.Physiol.Cell.Physiol_295_C807 |
| PubMedSearch : Ye_2008_Am.J.Physiol.Cell.Physiol_295_C807 |
| PubMedID: 18650266 |
| Gene_locus related to this paper: pseae-PA2934 |
| Title : Cif is negatively regulated by the TetR family repressor CifR - MacEachran_2008_Infect.Immun_76_3197 |
| Author(s) : Maceachran DP , Stanton BA , O'Toole GA |
| Ref : Infect Immun , 76 :3197 , 2008 |
| Abstract : MacEachran_2008_Infect.Immun_76_3197 |
| ESTHER : MacEachran_2008_Infect.Immun_76_3197 |
| PubMedSearch : MacEachran_2008_Infect.Immun_76_3197 |
| PubMedID: 18458065 |
| Gene_locus related to this paper: pseae-PA2934 |
| Title : The Pseudomonas aeruginosa secreted protein PA2934 decreases apical membrane expression of the cystic fibrosis transmembrane conductance regulator - MacEachran_2007_Infect.Immun_75_3902 |
| Author(s) : Maceachran DP , Ye S , Bomberger JM , Hogan DA , Swiatecka-Urban A , Stanton BA , O'Toole GA |
| Ref : Infect Immun , 75 :3902 , 2007 |
| Abstract : MacEachran_2007_Infect.Immun_75_3902 |
| ESTHER : MacEachran_2007_Infect.Immun_75_3902 |
| PubMedSearch : MacEachran_2007_Infect.Immun_75_3902 |
| PubMedID: 17502391 |
| Gene_locus related to this paper: pseae-PA2934 |