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staep-GEHD

Staphylococcus epidermidis EH46 lipase precursor (EC 3.1.1.3) GehD SEL-2 serp2388

Comment

EH46 promiscuous activity 23\/96 substrates Martinez-Martinez et al. 2018 || Rosenstein R, Gotz F a review on Staphylococcal lipases. There is a long precursor which is cut to a 46kDa active form

Relationship

Family : Bacterial_lip_FamI.6

Block : L

Position in NCBI Life Tree : Staphylococcus epidermidis

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

VHKIGNTKTD KTVKTNQKKQ TSLTSPRVVK SKQTKHINQL TAQAQYKNQY PVVFVHGFVG LVGEDAFSMY PNYWGGIKYN VKKELTKLGY RVHEANVGAF SSNYDRAVEL YYYIKGGRVD YGAAHAAKYG HKRYGRTYEG IMPDWEPGKK IHLVGHSMGG QTIRLMEHFL RNGNQEEIDY QRQYGGTVSD LFKGGQDNMV STITTLGTPH NGTPAADKLG STKFIKDTIN RIGKIGGTKA LDLELGFSQW GFKQQPNESY AEYAKRIANS KVWETEDQAV NDLTTAGAEK LNQMTTLNPN IVYTSYTGAA THTGPLGNEV PNIRQFPLFD LTSRVIGGDD NKNVRVNDGI VPVSSSLHPS DEAFKKVGMM NLATDKGIWQ VRPVQYDWDH LDLVGLDTTD YKRTGEELGQ FYMSMINNML KVEELDGITR K

References

Title : Effects of alcohol concentration and temperature on the dynamics and stability of mutant Staphylococcal lipase - Ong_2023_J.Biomol.Struct.Dyn__1
Author(s) : Ong SN , Kamarudin NHA , Shariff FM , Noor NDM , Ali MSM , Rahman R
Ref : J Biomol Struct Dyn , :1 , 2023
Abstract : Ong_2023_J.Biomol.Struct.Dyn__1
ESTHER : Ong_2023_J.Biomol.Struct.Dyn__1
PubMedSearch : Ong_2023_J.Biomol.Struct.Dyn__1
PubMedID: 37968883
Gene_locus related to this paper: staep-GEHD

Title : Characterization of Serine Hydrolases Across Clinical Isolates of Commensal Skin Bacteria Staphylococcus epidermidis Using Activity-Based Protein Profiling - Keller_2020_ACS.Infect.Dis_6_930
Author(s) : Keller LJ , Lentz CS , Chen YE , Metivier RJ , Weerapana E , Fischbach MA , Bogyo M
Ref : ACS Infect Dis , 6 :930 , 2020
Abstract : Keller_2020_ACS.Infect.Dis_6_930
ESTHER : Keller_2020_ACS.Infect.Dis_6_930
PubMedSearch : Keller_2020_ACS.Infect.Dis_6_930
PubMedID: 32298574
Gene_locus related to this paper: staep-GEHD , staep-lipas , staep-SE0226 , staep-SE0245 , staep-SE0424 , staep-SE0564 , staep-SE0714 , staep-SE0980 , staep-SE1460 , staep-SE1780 , staep-SERP2035 , staep-SE2095 , staep-SE2213 , staep-SE2328 , staep-SE2403

Title : Determinants and prediction of esterase substrate promiscuity patterns - Martinez-Martinez_2018_ACS.Chem.Biol_13_225
Author(s) : Martinez-Martinez M , Coscolin C , Santiago G , Chow J , Stogios PJ , Bargiela R , Gertler C , Navarro-Fernandez J , Bollinger A , Thies S , Mendez-Garcia C , Popovic A , Brown G , Chernikova TN , Garcia-Moyano A , Bjergah GE , Perez-Garcia P , Hai T , Del Pozo MV , Stokke R , Steen IH , Cui H , Xu X , Nocek BP , Alcaide M , Distaso M , Mesa V , Pelaez AI , Sanchez J , Buchholz PCF , Pleiss J , Fernandez-Guerra A , Glockner FO , Golyshina OV , Yakimov MM , Savchenko A , Jaeger KE , Yakunin AF , Streit WR , Golyshin PN , Guallar V , Ferrer M
Ref : ACS Chemical Biology , 13 :225 , 2018
Abstract : Martinez-Martinez_2018_ACS.Chem.Biol_13_225
ESTHER : Martinez-Martinez_2018_ACS.Chem.Biol_13_225
PubMedSearch : Martinez-Martinez_2018_ACS.Chem.Biol_13_225
PubMedID: 29182315
Gene_locus related to this paper: 9zzzz-a0a2k8jn75 , 9zzzz-a0a2k8jt94 , 9zzzz-a0a0g3fj44 , 9zzzz-a0a0g3fh10 , 9zzzz-a0a0g3fh03 , 9bact-a0a1s5qkj8 , 9zzzz-a0a0g3feh5 , 9zzzz-a0a0g3fkz4 , 9zzzz-a0a0g3fh07 , 9zzzz-a0a0g3fh34 , 9zzzz-a0a0g3fh31 , 9bact-KY458167 , alcbs-q0vqa3 , 9bact-a0a1s5qki8 , 9zzzz-a0a0g3feq8 , 9zzzz-a0a0g3feh8 , 9zzzz-a0a0g3fh19 , 9bact-KY203037 , 9bact-a0a1s5ql22 , 9bact-a0a1s5qm34 , 9bact-KY203034 , 9bact-r9qzg0 , 9bact-a0a1s5qly8 , 9zzzz-a0a0g3fkz8 , 9zzzz-a0a0g3feg9 , 9zzzz-KY203033 , 9zzzz-a0a0g3fes4 , 9zzzz-a0a0g3fh42 , 9bact-a0a1s5qlx2 , 9zzzz-KY483651 , 9bact-a0a1s5qmh4 , 9zzzz-KY203032 , 9zzzz-EH87 , 9zzzz-a0a0g3fei1 , 9zzzz-a0a0g3fet2 , 9zzzz-KY483647 , 9zzzz-EH82 , 9zzzz-a0a0g3fe15 , 9bact-KY203031 , 9bact-t1w006 , 9zzzz-a0a0g3fet6 , 9bact-KY458164 , geoth-g8myf3 , 9bact-a0a1s5ql04 , 9gamm-a0a1y0ihk7 , 9bact-a0a1s5qly6 , 9bact-a0a1s5qkg4 , 9bact-a0a1s5qkm4 , 9gamm-s5tv80 , 9gamm-a0a0c4zhg2 , 9zzzz-t1b379 , 9gamm-KY483646 , 9bact-KY458160 , 9zzzz-a0a0g3fj57 , 9gamm-s5t8349 , 9arch-KY203036 , 9bact-KY458168 , 9zzzz-a0a0g3fes0 , 9zzzz-t1be47 , 9bact-KY458159 , 9zzzz-a0a0g3fh39 , 9bact-t1vzd5 , 9prot-EH41 , 9bact-Lip114 , alcbs-q0vt77 , 9bact-a0a1s5qke6 , 9bact-a0a1s5qkf3 , 9prot-SRP030024 , 9gamm-s5t532 , 9bact-a0a1s5qkl2 , 9bact-a0a1s5qkk8 , 9zzzz-KY203030 , 9zzzz-t1d4I7 , 9prot-KY019260 , 9bact-a0a1s5qm38 , 9arch-KY458161 , 9prot-KY010302 , 9zzzz-a0a0g3fl25 , 9actn-KY010298 , 9gamm-s5u059 , 9bact-a0a1s5qmi7 , 9bact-KY010297 , 9bact-KY483642 , 9bact-a0a1s5qkj1 , 9bact-KY010299 , 9bact-KY483648 , alcbs-q0vtl7 , 9bact-a0a1s5qf1 , 9bact-a0a1s5qkg0 , 9bact-a0a0h4tgu6 , 9bact-MilE3 , 9bact-LAE6 , 9alte-MGS-MT1 , 9bact-r9qzf7 , 9gamm-k0c6t6 , alcbs-q0vl36 , alcbs-q0vlq1 , alcbs-q0vq49 , bacsu-pnbae , canar-LipB , canan-lipasA , geost-lipas , marav-a1u5n0 , pseps-i7k8x5 , staep-GEHD , symth-q67mr3 , altma-s5cfn7 , cycsp-k0c2b8 , alcbs-q0vlk5 , 9bact-k7qe48 , 9bact-MGS-M1 , 9bact-MGS-M2 , 9bact-a0a0b5kns5 , 9zzzz-a0a0g3fej4 , 9zzzz-a0a0g3fj60 , 9zzzz-a0a0g3fej0 , 9zzzz-a0a0g3fj64 , 9bact-a0a0b5kc16 , 9zzzz-a0a0g3feg6 , 9zzzz-a0a0g3feu6

Title : Expression of an organic solvent stable lipase from Staphylococcus epidermidis AT2 - Rahman_2010_Int.J.Mol.Sci_11_3195
Author(s) : Rahman RNZRA , Kamarudin NH , Yunus J , Salleh AB , Basri M
Ref : Int J Mol Sci , 11 :3195 , 2010
Abstract : Rahman_2010_Int.J.Mol.Sci_11_3195
ESTHER : Rahman_2010_Int.J.Mol.Sci_11_3195
PubMedSearch : Rahman_2010_Int.J.Mol.Sci_11_3195
PubMedID: 20957088
Gene_locus related to this paper: staep-GEHD

Title : Genome-based analysis of virulence genes in a non-biofilm-forming Staphylococcus epidermidis strain (ATCC 12228) - Zhang_2003_Mol.Microbiol_49_1577
Author(s) : Zhang YQ , Ren SX , Li HL , Wang YX , Fu G , Yang J , Qin ZQ , Miao YG , Wang WY , Chen RS , Shen Y , Chen Z , Yuan ZH , Zhao GP , Qu D , Danchin A , Wen YM
Ref : Molecular Microbiology , 49 :1577 , 2003
Abstract : Zhang_2003_Mol.Microbiol_49_1577
ESTHER : Zhang_2003_Mol.Microbiol_49_1577
PubMedSearch : Zhang_2003_Mol.Microbiol_49_1577
PubMedID: 12950922
Gene_locus related to this paper: staep-GEHD , staep-lipas , staep-SE0011 , staep-SE0226 , staep-SE0386 , staep-SE0389 , staep-SE0424 , staep-SE0564 , staep-SE0714 , staep-SE0745 , staep-SE0980 , staep-SE1436 , staep-SE1460 , staep-SE1510 , staep-SE1780 , staep-SE1929 , staep-SERP2035 , staep-SE2050 , staep-SE2095 , staep-SE2213 , staep-SE2328 , staep-SE2403

Title : Identification of a second lipase gene, gehD, in Staphylococcus epidermidis: comparison of sequence with those of other staphylococcal lipases - Longshaw_2000_Microbiology_146 ( Pt 6)_1419
Author(s) : Longshaw CM , Farrell AM , Wright JD , Holland KT
Ref : Microbiology , 146 ( Pt 6) :1419 , 2000
Abstract : Longshaw_2000_Microbiology_146 ( Pt 6)_1419
ESTHER : Longshaw_2000_Microbiology_146 ( Pt 6)_1419
PubMedSearch : Longshaw_2000_Microbiology_146 ( Pt 6)_1419
PubMedID: 10846220
Gene_locus related to this paper: staep-GEHD