2-Bromopalmitate
General
Type : Fatty acid,Hexadecanoate,Palmitate
Chemical_Nomenclature : (2R)-2-bromohexadecanoic acid
Canonical SMILES : CCCCCCCCCCCCCCC(C(=O)O)Br
InChI : InChI=1S\/C16H31BrO2\/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15(17)16(18)19\/h15H,2-14H2,1H3,(H,18,19)\/t15-\/m1\/s1
InChIKey : DPRAYRYQQAXQPE-OAHLLOKOSA-N
Other name(s) : (R)-2-Bromohexadecanoic acid,(2R)-2-bromohexadecanoic acid,SCHEMBL3954525,ZINC14278029,UNII-7EI4G5X28Z,J1W
MW : 335.32
Formula : C16H31BrO2
CAS_number :
PubChem : 11056766
UniChem : DPRAYRYQQAXQPE-OAHLLOKOSA-N
IUPHAR :
Wikipedia :
Target
Families : 2-Bromopalmitate ligand of proteins in family: LYsophospholipase_carboxylesterase
Stucture : 6QGN Crystal structure of human acyl protein thioesterase APT1 bound to 2-Bromopalmitate
Protein : human-LYPLA1
References (2)
| Title : Palmitoylated acyl protein thioesterase APT2 deforms membranes to extract substrate acyl chains - Abrami_2021_Nat.Chem.Biol_17_438 |
| Author(s) : Abrami L , Audagnotto M , Ho S , Marcaida MJ , Mesquita FS , Anwar MU , Sandoz PA , Fonti G , Pojer F , Dal Peraro M , van der Goot FG |
| Ref : Nat Chemical Biology , 17 :438 , 2021 |
| Abstract : Abrami_2021_Nat.Chem.Biol_17_438 |
| ESTHER : Abrami_2021_Nat.Chem.Biol_17_438 |
| PubMedSearch : Abrami_2021_Nat.Chem.Biol_17_438 |
| PubMedID: 33707782 |
| Gene_locus related to this paper: human-LYPLA1 , human-LYPLA2 |
| Title : 2-Bromopalmitate reduces protein deacylation by inhibition of acyl-protein thioesterase enzymatic activities - Pedro_2013_PLoS.One_8_e75232 |
| Author(s) : Pedro MP , Vilcaes AA , Tomatis VM , Oliveira RG , Gomez GA , Daniotti JL |
| Ref : PLoS ONE , 8 :e75232 , 2013 |
| Abstract : Pedro_2013_PLoS.One_8_e75232 |
| ESTHER : Pedro_2013_PLoS.One_8_e75232 |
| PubMedSearch : Pedro_2013_PLoS.One_8_e75232 |
| PubMedID: 24098372 |