4-Mercuriphenylsulfonate
Compounds inhibiting cysteine - dependant enzymes, so not really inhibitors of serine hydrolases, but used as tools whene active serine is mutated to cysteins
General
Type : Sulfur Compound
Chemical_Nomenclature : (4-sulfophenyl)mercury
Canonical SMILES : C1=CC(=CC=C1S(=O)(=O)O)[Hg]
InChI : InChI=1S\/C6H5O3S.Hg\/c7-10(8,9)6-4-2-1-3-5-6\;\/h2-5H,(H,7,8,9)\;
InChIKey : KQAOIKIZSJJTII-UHFFFAOYSA-N
Other name(s) : 4-Mercuriphenylsulfonate,Para-mercury-benzensulfonic acid,P-mercuribenzenesulfonic acid,PMBS
MW : 357.75
Formula : C6H5HgO3S
CAS_number : 17014-79-8
PubChem : 65258
UniChem : KQAOIKIZSJJTII-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
Families : 4-Mercuriphenylsulfonate ligand of proteins in family: Cutinase
Stucture : 1XZC Fusarium solani cutinase S129C mutant + para-sulfurousphenylmercury
Protein : fusso-cutas
References (2)
| Title : Dynamics of Fusarium solani cutinase investigated through structural comparison among different crystal forms of its variants - Longhi_1996_Proteins_26_442 |
| Author(s) : Longhi S , Nicolas A , Creveld L , Egmond M , Verrips CT , de Vlieg J , Martinez C , Cambillau C |
| Ref : Proteins , 26 :442 , 1996 |
| Abstract : Longhi_1996_Proteins_26_442 |
| ESTHER : Longhi_1996_Proteins_26_442 |
| PubMedSearch : Longhi_1996_Proteins_26_442 |
| PubMedID: 8990497 |
| Gene_locus related to this paper: fusso-cutas |
| Title : Engineering cysteine mutants to obtain crystallographic phases with a cutinase from Fusarium solani pisi - Martinez_1993_Protein.Eng_6_157 |
| Author(s) : Martinez C , de Geus P , Stanssens P , Lauwereys M , Cambillau C |
| Ref : Protein Engineering , 6 :157 , 1993 |
| Abstract : Martinez_1993_Protein.Eng_6_157 |
| ESTHER : Martinez_1993_Protein.Eng_6_157 |
| PubMedSearch : Martinez_1993_Protein.Eng_6_157 |
| PubMedID: 8475042 |
| Gene_locus related to this paper: fusso-cutas |