Bis(N-propylcarbamic-acid)ethylene-ester
1,2-Ethylene-di-N-n-propylcarbamate is an essential activator of Pseudomonas species lipase while 1,2-ethylene-di-N-n-butyl-, t-butyl-, n-heptyl-, and n-octyl-carbamates are inhibitors in the presence of the detergent taurocholate or triton X-100. It binds outside the active site of PSL and probably at the co-lipase binding site of Pseudomonas species lipase
General
Type : Carbamate
Chemical_Nomenclature : 2-(propylcarbamoyloxy)ethyl N-propylcarbamate
Canonical SMILES : CCCNC(=O)OCCOC(=O)NCCC
InChI : InChI=1S\/C10H20N2O4\/c1-3-5-11-9(13)15-7-8-16-10(14)12-6-4-2\/h3-8H2,1-2H3,(H,11,13)(H,12,14)
InChIKey : HYFRFSBFAPEDJM-UHFFFAOYSA-N
Other name(s) : Bis(N-propylcarbamic acid)ethylene ester,1,2-Ethylene-di-N-n-propylcarbamate
MW : 232.28
Formula : C10H20N2O4
CAS_number :
PubChem : 101852196
UniChem : HYFRFSBFAPEDJM-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
ethylene-ester.gif)
Target
Families : Bis(N-propylcarbamic-acid)ethylene-ester ligand of proteins in family: Bacterial_lip_FamI.1
Stucture :
Protein : pseae-llipa
References (1)
| Title : Inhibition or activation of Pseudomonas species lipase by 1,2-ethylene-di-N-alkylcarbamates in detergents - Lin_2007_Chem.Phys.Lipids_146_85 |
| Author(s) : Lin MC , Lu CP , Cheng YR , Lin YF , Lin CS , Lin G |
| Ref : Chemistry & Physic of Lipids , 146 :85 , 2007 |
| Abstract : Lin_2007_Chem.Phys.Lipids_146_85 |
| ESTHER : Lin_2007_Chem.Phys.Lipids_146_85 |
| PubMedSearch : Lin_2007_Chem.Phys.Lipids_146_85 |
| PubMedID: 17274971 |