Bromophenyl-tacrine6i
General
Type : Derivative of Tacrine
Chemical_Nomenclature : Ethyl 5-amino-4-(3-bromophenyl)-2-phenyl-6,7,8,9-tetrahydro-4H-pyrano [2,3-b]quinoline-3-carboxylate
Canonical SMILES : CCOC(=O)C1=C(OC4=C(C1C2=CC(=CC=C2)Br)C(=C3CCCCC3=N4)N)C5=CC=CC=C5
InChI : InChI=1S\/C27H25BrN2O3\/c1-2-32-27(31)23-21(17-11-8-12-18(28)15-17)22-24(29)19-13-6-7-14-20(19)30-26(22)33-25(23)16-9-4-3-5-10-16\/h3-5,8-12,15,21H,2,6-7,13-14H2,1H3,(H2,29,30)
InChIKey : PVQMHOFRGQMXAP-UHFFFAOYSA-N
Other name(s) : CHEMBL4077932
MW : 505.40
Formula : C27H25BrN2O3
CAS_number :
PubChem : 137649792
UniChem : PVQMHOFRGQMXAP-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
References (1)
| Title : New tacrine-derived AChE\/BuChE inhibitors: Synthesis and biological evaluation of 5-amino-2-phenyl-4H-pyrano[2,3-b]quinoline-3-carboxylates - Eghtedari_2017_Eur.J.Med.Chem_128_237 |
| Author(s) : Eghtedari M , Sarrafi Y , Nadri H , Mahdavi M , Moradi A , Homayouni Moghadam F , Emami S , Firoozpour L , Asadipour A , Sabzevari O , Foroumadi A |
| Ref : Eur Journal of Medicinal Chemistry , 128 :237 , 2017 |
| Abstract : Eghtedari_2017_Eur.J.Med.Chem_128_237 |
| ESTHER : Eghtedari_2017_Eur.J.Med.Chem_128_237 |
| PubMedSearch : Eghtedari_2017_Eur.J.Med.Chem_128_237 |
| PubMedID: 28189905 |