CyC-8beta

General

Type : Organophosphate,Cyclic OP,Lipase inhibitor

Chemical_Nomenclature : methyl (2R,5R)-5-dodecyl-2-methoxy-7-methyl-2-oxo-4,5-dihydro-3H-1,2$l^{5}-oxaphosphepine-6-carboxylate

Canonical SMILES : CCCCCCCCCCCCC1CCP(=O)(OC(=C1C(=O)OC)C)OC

InChI : InChI=1S\/C21H39O5P\/c1-5-6-7-8-9-10-11-12-13-14-15-19-16-17-27(23,25-4)26-18(2)20(19)21(22)24-3\/h19H,5-17H2,1-4H3\/t19-,27-\/m1\/s1

InChIKey : ZWCSIELZWHDDDD-XHCCPWGMSA-N

Other name(s) : CyC8b,CyC-8b,9SW


MW : 402.51

Formula : C21H39O5P

CAS_number :

PubChem : 71457279

UniChem : ZWCSIELZWHDDDD-XHCCPWGMSA-N

IUPHAR :

Wikipedia :

Target

Families : CyC-8beta ligand of proteins in family: A85-Mycolyl-transferase

Stucture :

Protein : myctu-a85c

References (1)

Title : Cyclipostins and cyclophostin analogs inhibit the antigen 85C from Mycobacterium tuberculosis both in vitro and in vivo - Viljoen_2018_J.Biol.Chem_293_2755
Author(s) : Viljoen A , Richard M , Nguyen PC , Fourquet P , Camoin L , Paudal RR , Gnawali GR , Spilling CD , Cavalier JF , Canaan S , Blaise M , Kremer L
Ref : Journal of Biological Chemistry , 293 :2755 , 2018
Abstract : Viljoen_2018_J.Biol.Chem_293_2755
ESTHER : Viljoen_2018_J.Biol.Chem_293_2755
PubMedSearch : Viljoen_2018_J.Biol.Chem_293_2755
PubMedID: 29301937
Gene_locus related to this paper: myctu-a85c