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Inhibitor Report for: Diazepan-AJH

General
Type Trifluoro, Diazepan, Azepane
Chemical_Nomenclature 4-[4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-1,4-diazepane-1-carbonyl]benzoic acid
Canonical SMILES C1CN(CCN(C1)C(=O)C2=CC=C(C=C2)C(=O)O)C(=O)CC(CC3=CC(=C(C=C3F)F)F)N
InChI InChI=1S/C23H24F3N3O4/c24-18-13-20(26)19(25)11-16(18)10-17(27)12-21(30)28-6-1-7-29(9-8-28)22(31)14-2-4-15(5-3-14)23(32)33/h2-5,11,13,17H,1,6-10,12,27H2,(H,32,33)/t17-/m1/s1
InChIKey NXUBRAZWHJADLI-QGZVFWFLSA-N
Other name(s) AJH ; CHEMBL482154 ; CHEMBL1186902 ; BDBM50256569 ; (R)-4-(4-(3-amino-4-(2,4,5-trifluorophenyl)butanoyl)-1,4-diazepane-1-carbonyl)benzoic acid hydrochloride ; 4-({4-[(3r)-3-Amino-4-(2,4,5-Trifluorophenyl)butanoyl]-1,4-Diazepan-1-Yl}carbonyl)benzoic Acid
________________________________________________________________________________________________
MW|463.45
Formula|C23H24F3N3O4
CAS_number|
PubChem|25021195
UniChem|NXUBRAZWHJADLI-QGZVFWFLSA-N
IUPHAR|
Wikipedia|

Target
Families | Diazepan-AJH ligand of proteins in family: DPP4N_Peptidase_S9
Stucture | 1 structure: 3EIO: Crystal Structure Analysis of DPPIV Inhibitor
Protein | human-DPP4

References:
Search PubMed for references concerning: Diazepan-AJH
    Title: Synthesis and biological evaluation of homopiperazine derivatives with beta-aminoacyl group as dipeptidyl peptidase IV inhibitors
    Ahn JH, Park WS, Jun MA, Shin MS, Kang SK, Kim KY, Rhee SD, Bae MA, Kim KR and Kim SS <7 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 18:6525, 2008 : PubMed

            

    Title: Synthesis and biological evaluation of pyrazoline analogues with beta-amino acyl group as dipeptidyl peptidase IV inhibitors
    Jun MA, Park WS, Kang SK, Kim KY, Kim KR, Rhee SD, Bae MA, Kang NS, Sohn SK and Ahn JH <5 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 43:1889, 2008 : PubMed