Donepezil-Melatonin-4u
General
Type : Derivative of Donepezil,Derivative of Tryptamine,Indole,Alkyl linked bis-ligand,Multitarget,Antioxidant
Chemical_Nomenclature : N-[2-(1-benzylpiperidin-4-yl)ethyl]-3-(1H-indol-3-yl)propanamide
Canonical SMILES : C1CN(CCC1CCNC(=O)CCC2=CNC3=CC=CC=C32)CC4=CC=CC=C4
InChI : InChI=1S\/C25H31N3O\/c29-25(11-10-22-18-27-24-9-5-4-8-23(22)24)26-15-12-20-13-16-28(17-14-20)19-21-6-2-1-3-7-21\/h1-9,18,20,27H,10-17,19H2,(H,26,29)
InChIKey : WXTKBXGKRLFVQP-UHFFFAOYSA-N
Other name(s) : CHEMBL3824248,SCHEMBL3147014,BDBM50187201,J3.561.706J,N-[2-(1-Benzyl-4-piperidinyl)ethyl]-1H-indole-3-propanamide
MW : 389.5
Formula : C25H31N3O
CAS_number :
PubChem : 11625278
UniChem : WXTKBXGKRLFVQP-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
References (1)
| Title : Synthesis and evaluation of multi-target-directed ligands for the treatment of Alzheimer's disease based on the fusion of donepezil and melatonin - Wang_2016_Bioorg.Med.Chem_24_4324 |
| Author(s) : Wang J , Wang ZM , Li XM , Li F , Wu JJ , Kong LY , Wang XB |
| Ref : Bioorganic & Medicinal Chemistry , 24 :4324 , 2016 |
| Abstract : Wang_2016_Bioorg.Med.Chem_24_4324 |
| ESTHER : Wang_2016_Bioorg.Med.Chem_24_4324 |
| PubMedSearch : Wang_2016_Bioorg.Med.Chem_24_4324 |
| PubMedID: 27460699 |