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Inhibitor Report for: Flouroolefin-2

General
Type Sulfur Compound, Cyclopropyl, Oxadiazol, Sulfonyl
Chemical_Nomenclature (2S,3S)-3-[3-(2-chloro-4-methylsulfonylphenyl)-1,2,4-oxadiazol-5-yl]-1-cyclopentylidene-4-cycloprop-2-en-1-yl-1-fluorobutan-2-amine
Canonical SMILES CS(=O)(=O)C1=CC(=C(C=C1)C2=NOC(=N2)C(CC3C=C3)C(C(=C4CCCC4)F)N)Cl
InChI InChI=1S/C21H23ClFN3O3S/c1-30(27,28)14-8-9-15(17(22)11-14)20-25-21(29-26-20)16(10-12-6-7-12)19(24)18(23)13-4-2-3-5-13/h6-9,11-12,16,19H,2-5,10,24H2,1H3/t16-,19-/m0/s1
InChIKey KAFTWRNSMBZRAP-LPHOPBHVSA-N XCCSSVMRGIQMGF-LPHOPBHVSA-N
Other name(s) 317 ; CHEMBL402163 ; CHEMBL1185242 ; BDBM50374938 ; DB06994 ; (2S,3S)-3-[3-(2-chloro-4-methanesulfonylphenyl)-1,2,4-oxadiazol-5-yl]-1-[(1Z)-cyclopentylidene]-4-cyclopropyl-1-fluorobutan-2-amine
________________________________________________________________________________________________
MW|451.94
Formula|C21H23ClFN3O3S
CAS_number|
PubChem|44629664, 24768547
UniChem|KAFTWRNSMBZRAP-LPHOPBHVSA-N, XCCSSVMRGIQMGF-LPHOPBHVSA-N
IUPHAR|
Wikipedia|

Target
Families | Flouroolefin-2 ligand of proteins in family: DPP4N_Peptidase_S9
Stucture | 1 structure: 3C45: Human dipeptidyl peptidase IV/CD26 in complex with a flouroolefin inhibitor 2
Protein | human-DPP4

References:
Search PubMed for references concerning: Flouroolefin-2
    Title: Fluoroolefins as amide bond mimics in dipeptidyl peptidase IV inhibitors
    Edmondson SD, Wei L, Xu J, Shang J, Xu S, Pang J, Chaudhary A, Dean DC, He H and Weber AE <8 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 18:2409, 2008 : PubMed