Geranylphenazinediol from Streptomyces sp. strain LB173. This strain was isolated from ambient sediment of a Saccharina latissima specimen growing in the Kiel Fjord.IC50 geranylphenazinediol 2.62+/- 0.35 microM
Type : Natural,Phenazine
Chemical_Nomenclature : 9-[(2E)-3,7-dimethylocta-2,6-dienyl]-6-hydroxy-5H-phenazin-1-one
Canonical SMILES : C\/C(=CCc1ccc(c2c1nc1c(O)cccc1n2)O)\/CCC=C(C)C || CC(=CCCC(=CCC1=C2C(=C(C=C1)O)NC3=CC=CC(=O)C3=N2)C)C
InChI : InChI=1S\/C22H24N2O2\/c1-14(2)6-4-7-15(3)10-11-16-12-13-19(26)22-20(16)24-21-17(23-22)8-5-9-18(21)25\/h5-6,8-10,12-13,25-26H,4,7,11H2,1-3H3\/b15-10+
InChIKey : KMFWEUARPSOWSB-XNTDXEJSSA-N
Other name(s) : Geranyl-phenazine-diol,CHEMBL2071424,BDBM50390003
MW : 348.43
Formula : C22H24N2O2
CAS_number :
PubChem : 60201712
UniChem : KMFWEUARPSOWSB-XNTDXEJSSA-N
IUPHAR :
Wikipedia :
Title : Geranylphenazinediol, an acetylcholinesterase inhibitor produced by a Streptomyces species - Ohlendorf_2012_J.Nat.Prod_75_1400 |
Author(s) : Ohlendorf B , Schulz D , Erhard A , Nagel K , Imhoff JF |
Ref : Journal of Natural Products , 75 :1400 , 2012 |
Abstract : Ohlendorf_2012_J.Nat.Prod_75_1400 |
ESTHER : Ohlendorf_2012_J.Nat.Prod_75_1400 |
PubMedSearch : Ohlendorf_2012_J.Nat.Prod_75_1400 |
PubMedID: 22775474 |