Germinone-A
not to be confounded with 2H-germine 1-oxide also called germinone || IC50 (nM)with YLG as substrate: rac-GR24, AT14 32.9 +/- 6.0; Germinone AT14 12.2 +/- 10; KAI2 585 +/- 36; dMgerminone AT14 162 +/- 9.0; KAI2 46.4 +/- 3.0
General
Type : Strigolactone,Debranone,Strigolactone receptors ligand
Chemical_Nomenclature : 5-(4-Phenyl-2-nitrophenoxy)-3-methylfuran-2(5H)-one
Canonical SMILES : C1(=C(C=CC(=C1)C2=CC=CC=C2)OC3C=C(C(O3)=O)C)[N+](=O)[O-]
InChI : InChI=1S\/C17H13NO5\/c1-11-9-16(23-17(11)19)22-15-8-7-13(10-14(15)18(20)21)12-5-3-2-4-6-12\/h2-10,16H,1H3
InChIKey : KEACYGRJKSMAJH-UHFFFAOYSA-N
Other name(s) :
MW : 311.29
Formula : C17H13NO5
CAS_number :
PubChem :
UniChem : KEACYGRJKSMAJH-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
Families : Germinone-A ligand of proteins in family: RsbQ-like
Stucture :
Protein : arath-KAI2.D14L || arath-AtD14
References (2)
| Title : Desmethyl type germinone, a specific agonist for the HTL\/KAI2 receptor, induces the Arabidopsis seed germination in a gibberellin-independent manner - Okabe_2023_Biochem.Biophys.Res.Commun_649_110 |
| Author(s) : Okabe S , Kitaoka K , Suzuki T , Kuruma M , Hagihara S , Yamaguchi S , Fukui K , Seto Y |
| Ref : Biochemical & Biophysical Research Communications , 649 :110 , 2023 |
| Abstract : Okabe_2023_Biochem.Biophys.Res.Commun_649_110 |
| ESTHER : Okabe_2023_Biochem.Biophys.Res.Commun_649_110 |
| PubMedSearch : Okabe_2023_Biochem.Biophys.Res.Commun_649_110 |
| PubMedID: 36764113 |
| Title : Synthetic agonist of HTL\/KAI2 shows potent stimulating activity for Arabidopsis seed germination - Fukui_2019_Bioorg.Med.Chem.Lett_29_2487 |
| Author(s) : Fukui K , Arai K , Kasahara H , Asami T , Hayashi KI |
| Ref : Bioorganic & Medicinal Chemistry Lett , 29 :2487 , 2019 |
| Abstract : Fukui_2019_Bioorg.Med.Chem.Lett_29_2487 |
| ESTHER : Fukui_2019_Bioorg.Med.Chem.Lett_29_2487 |
| PubMedSearch : Fukui_2019_Bioorg.Med.Chem.Lett_29_2487 |
| PubMedID: 31345632 |
| Gene_locus related to this paper: arath-KAI2.D14L |