Histidine

histidine does not, or only weakly inhibits, Hnl activity

General

Type : Peptide,Imidazole

Chemical_Nomenclature : (2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid

Canonical SMILES : C1=C(NC=N1)CC(C(=O)O)N

InChI : InChI=1S\/C6H9N3O2\/c7-5(6(10)11)1-4-2-8-3-9-4\/h2-3,5H,1,7H2,(H,8,9)(H,10,11)\/t5-\/m0\/s1

InChIKey : HNDVDQJCIGZPNO-YFKPBYRVSA-N

Other name(s) : His,L-histidine,Histidine,H-His-OH,Glyoxaline-5-alanine,Anti-rheuma


MW : 155.15

Formula : C6H9N3O2

CAS_number : 71-00-1

PubChem : 6274

UniChem : HNDVDQJCIGZPNO-YFKPBYRVSA-N

IUPHAR :

Wikipedia :

Target

Families : Histidine ligand of proteins in family: Hydroxynitrile_lyase

Stucture : 1YAS Rubber tree hydroxynitrile lyase + histidine

Protein : hevbr-hnl

References (3)

Title : Hydroxynitrile lyase from Hevea brasiliensis: molecular characterization and mechanism of enzyme catalysis - Hasslacher_1997_Proteins_27_438
Author(s) : Hasslacher M , Kratky C , Griengl H , Schwab H , Kohlwein SD
Ref : Proteins , 27 :438 , 1997
Abstract : Hasslacher_1997_Proteins_27_438
ESTHER : Hasslacher_1997_Proteins_27_438
PubMedSearch : Hasslacher_1997_Proteins_27_438
PubMedID: 9094745
Gene_locus related to this paper: hevbr-hnl

Title : Molecular cloning of the full-length cDNA of (S)-hydroxynitrile lyase from Hevea brasiliensis. Functional expression in Escherichia coli and Saccharomyces cerevisiae and identification of an active site residue - Hasslacher_1996_J.Biol.Chem_271_5884
Author(s) : Hasslacher M , Schall M , Hayn M , Griengl H , Kohlwein SD , Schwab H
Ref : Journal of Biological Chemistry , 271 :5884 , 1996
Abstract : Hasslacher_1996_J.Biol.Chem_271_5884
ESTHER : Hasslacher_1996_J.Biol.Chem_271_5884
PubMedSearch : Hasslacher_1996_J.Biol.Chem_271_5884
PubMedID: 8621461
Gene_locus related to this paper: hevbr-hnl

Title : Mechanism of cyanogenesis: the crystal structure of hydroxynitrile lyase from Hevea brasiliensis - Wagner_1996_Structure_4_811
Author(s) : Wagner UG , Hasslacher M , Griengl H , Schwab H , Kratky C
Ref : Structure , 4 :811 , 1996
Abstract : Wagner_1996_Structure_4_811
ESTHER : Wagner_1996_Structure_4_811
PubMedSearch : Wagner_1996_Structure_4_811
PubMedID: 8805565
Gene_locus related to this paper: hevbr-hnl