Imidocarb

Imidocarb is a urea derivative used in veterinary medicine as an antiprotozoal agent for the treatment of infection with Babesia and other parasites. Poor inhibitor of butyrylcholinesterase. Imidocarb dipropionate; 55750-06-6; Imidocarb (dipropionate) is the formulated drug

General

Type : Urea derivative,Drug

Chemical_Nomenclature : 1,3-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea

Canonical SMILES : C1CN=C(N1)C2=CC(=CC=C2)NC(=O)NC3=CC=CC(=C3)C4=NCCN4

InChI : InChI=1S\/C19H20N6O\/c26-19(24-15-5-1-3-13(11-15)17-20-7-8-21-17)25-16-6-2-4-14(12-16)18-22-9-10-23-18\/h1-6,11-12H,7-10H2,(H,20,21)(H,22,23)(H2,24,25,26)

InChIKey : SCEVFJUWLLRELN-UHFFFAOYSA-N

Other name(s) : Imidocarbum,Imidocarbe,CHEMBL427342,SCHEMBL203921,ZINC73661,CHEBI:51804,Imidocarb dipropionate,55750-06-6,Imidocarb (dipropionate),Imidocarb propionate


MW : 348.4

Formula : C19H20N6O

CAS_number : 27885-92-3

PubChem : 21389

UniChem : SCEVFJUWLLRELN-UHFFFAOYSA-N

IUPHAR :

Wikipedia :

Target

Families :

Stucture :

Protein :

References (6)

Title : Repurposing of the Malaria Box for Babesia microti in mice identifies novel active scaffolds against piroplasmosis - Rizk_2022_Parasit.Vectors_15_329
Author(s) : Rizk MA , Baghdadi HB , El-Sayed SAE , Eltaysh R , Igarashi I
Ref : Parasit Vectors , 15 :329 , 2022
Abstract : Rizk_2022_Parasit.Vectors_15_329
ESTHER : Rizk_2022_Parasit.Vectors_15_329
PubMedSearch : Rizk_2022_Parasit.Vectors_15_329
PubMedID: 36123705

Title : Imidocarb dipropionate in the treatment of Anaplasma marginale in cattle: Effects on enzymes of the antioxidant, cholinergic, and adenosinergic systems - Doyle_2016_Microb.Pathog_97_226
Author(s) : Doyle RL , Fritzen A , Bottari NB , Alves MS , da Silva AD , Morsch VM , Schetinger MR , Martins JR , Santos JS , Machado G , Da Silva AS
Ref : Microb Pathog , 97 :226 , 2016
Abstract : Doyle_2016_Microb.Pathog_97_226
ESTHER : Doyle_2016_Microb.Pathog_97_226
PubMedSearch : Doyle_2016_Microb.Pathog_97_226
PubMedID: 27301742

Title : Determination of whole blood cholinesterase in different animal species using specific substrates - Tecles_2001_Res.Vet.Sci_70_233
Author(s) : Tecles F , Ceron JJ
Ref : Res Vet Sci , 70 :233 , 2001
Abstract : Tecles_2001_Res.Vet.Sci_70_233
ESTHER : Tecles_2001_Res.Vet.Sci_70_233
PubMedSearch : Tecles_2001_Res.Vet.Sci_70_233
PubMedID: 11676619

Title : Effect of induced hypomagnesaemia on the toxicity of imidocarb in calves - Michell_1986_Res.Vet.Sci_40_264
Author(s) : Michell AR , White DG , Higgins AJ , Moss P , Lees P
Ref : Res Vet Sci , 40 :264 , 1986
Abstract : Michell_1986_Res.Vet.Sci_40_264
ESTHER : Michell_1986_Res.Vet.Sci_40_264
PubMedSearch : Michell_1986_Res.Vet.Sci_40_264
PubMedID: 3704346

Title : Some effects of imidocarb in goats - Ali_1985_Vet.Hum.Toxicol_27_477
Author(s) : Ali BH , Hassan T , Suliman HB , Abdelsalam EB
Ref : Vet Hum Toxicol , 27 :477 , 1985
Abstract : Ali_1985_Vet.Hum.Toxicol_27_477
ESTHER : Ali_1985_Vet.Hum.Toxicol_27_477
PubMedSearch : Ali_1985_Vet.Hum.Toxicol_27_477
PubMedID: 4082455

Title : The kinetic constants for the inhibition of acetylcholinesterases by esters of phosphonodithioimidocarbonic acids -
Author(s) : Mehrotra KN , Lal S
Ref : Indian J Biochem , 7 :167 , 1970
PubMedID: 4252570