KK073

KK073 induced formation of the D14-D53 complex (KK052 inhibited SL-induced formation of the D14-D53 complex)

General

Type : Urea derivative,Trifluoro,Triazol

Chemical_Nomenclature : 1,2,3-triazol-1-yl-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]methanone

Canonical SMILES : FC(F)(F)c1ccc(cc1)N1CCN(CC1)C(=O)n1ccnn1

InChI : InChI=1S\/C14H14F3N5O\/c15-14(16,17)11-1-3-12(4-2-11)20-7-9-21(10-8-20)13(23)22-6-5-18-19-22\/h1-6H,7-10H2

InChIKey : HHQYTTYRIFYYCO-UHFFFAOYSA-N

Other name(s) : 9GU


MW : 325.29

Formula : C14H14F3N5O

CAS_number :

PubChem : 137348821

UniChem : HHQYTTYRIFYYCO-UHFFFAOYSA-N

IUPHAR :

Wikipedia :

Target

Families : KK073 ligand of proteins in family: RsbQ-like

Stucture : 5ZHT Crystal structure of OsD14 in complex with covalently bound KK073

Protein : orysj-Q10QA5

References (1)

Title : Triazole Ureas Covalently Bind to Strigolactone Receptor and Antagonize Strigolactone Responses - Nakamura_2019_Mol.Plant_12_44
Author(s) : Nakamura H , Hirabayashi K , Miyakawa T , Kikuzato K , Hu W , Xu Y , Jiang K , Takahashi I , Niiyama R , Dohmae N , Tanokura M , Asami T
Ref : Mol Plant , 12 :44 , 2019
Abstract : Nakamura_2019_Mol.Plant_12_44
ESTHER : Nakamura_2019_Mol.Plant_12_44
PubMedSearch : Nakamura_2019_Mol.Plant_12_44
PubMedID: 30391752
Gene_locus related to this paper: orysj-Q10QA5