Mercury-acetate
Compounds inhibiting cysteine - dependant enzymes, so not really inhibitors of serine hydrolases, but used as tools whene active serine is mutated to cysteins
General
Type :
Chemical_Nomenclature : mercury(1+)\;acetate
Canonical SMILES : CC(=O)[O-].[Hg+]
InChI : InChI=1S\/C2H4O2.Hg\/c1-2(3)4\;\/h1H3,(H,3,4)\;\/q\;+1\/p-1
InChIKey : WRYNUJYAXVDTCB-UHFFFAOYSA-M
Other name(s) : Mercurous acetate,Mercury acetate (HgOAc),Mercury acetate,Mercury monoacetate,Dimercury di(acetate),EINECS 211-161-3
MW : 259.63
Formula : C2H3HgO2
CAS_number : 631-60-7
PubChem : 61181
UniChem : WRYNUJYAXVDTCB-UHFFFAOYSA-M
IUPHAR :
Wikipedia :
Target
Families : Mercury-acetate ligand of proteins in family: Cutinase
Stucture : 1XZB Fusarium solani cutinase S129C mutant + mercury acetate
Protein : fusso-cutas
References (2)
| Title : Dynamics of Fusarium solani cutinase investigated through structural comparison among different crystal forms of its variants - Longhi_1996_Proteins_26_442 |
| Author(s) : Longhi S , Nicolas A , Creveld L , Egmond M , Verrips CT , de Vlieg J , Martinez C , Cambillau C |
| Ref : Proteins , 26 :442 , 1996 |
| Abstract : Longhi_1996_Proteins_26_442 |
| ESTHER : Longhi_1996_Proteins_26_442 |
| PubMedSearch : Longhi_1996_Proteins_26_442 |
| PubMedID: 8990497 |
| Gene_locus related to this paper: fusso-cutas |
| Title : Engineering cysteine mutants to obtain crystallographic phases with a cutinase from Fusarium solani pisi - Martinez_1993_Protein.Eng_6_157 |
| Author(s) : Martinez C , de Geus P , Stanssens P , Lauwereys M , Cambillau C |
| Ref : Protein Engineering , 6 :157 , 1993 |
| Abstract : Martinez_1993_Protein.Eng_6_157 |
| ESTHER : Martinez_1993_Protein.Eng_6_157 |
| PubMedSearch : Martinez_1993_Protein.Eng_6_157 |
| PubMedID: 8475042 |
| Gene_locus related to this paper: fusso-cutas |