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Inhibitor Report for: N-1-adamantyl-N'-cyclohexylurea

General
Type Adamantyl, Urea derivative
Chemical_Nomenclature 1-(1-adamantyl)-3-cyclohexylurea
Canonical SMILES C1CCC(CC1)NC(=O)NC23CC4CC(C2)CC(C4)C3
InChI InChI=1S/C17H28N2O/c20-16(18-15-4-2-1-3-5-15)19-17-9-12-6-13(10-17)8-14(7-12)11-17/h12-15H,1-11H2,(H2,18,19,20)
InChIKey VESXWSWSGQONHC-UHFFFAOYSA-N
Other name(s) ACU ; CHEMBL242255 ; N-1-adamantyl-N'-cyclohexylurea ; ST51030996 ; AC1NMPQQ ; Urea-based compound, 13 ; ChemDiv3_000178
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MW|276.42
Formula|C17H28N2O
CAS_number|
PubChem|5029871
UniChem|VESXWSWSGQONHC-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | N-1-adamantyl-N'-cyclohexylurea ligand of proteins in family: Epoxide_hydrolase
Protein | human-EPHX2

References:
Search PubMed for references concerning: N-1-adamantyl-N'-cyclohexylurea
    Title: Mammalian soluble epoxide hydrolase is identical to liver hepoxilin hydrolase
    Cronin A, Decker M, Arand M
    Ref: J Lipid Res, 52:712, 2011 : PubMed

            

    Title: Inhibition of the soluble epoxide hydrolase by tyrosine nitration
    Barbosa-Sicard E, Fromel T, Keseru B, Brandes RP, Morisseau C, Hammock BD, Braun T, Kruger M, Fleming I
    Ref: Journal of Biological Chemistry, 284:28156, 2009 : PubMed

            

    Title: Rapid determination of soluble epoxide hydrolase inhibitors in rat hepatic microsomes by high-performance liquid chromatography with electrospray tandem mass spectrometry
    Watanabe T, Hammock BD
    Ref: Analytical Biochemistry, 299:227, 2001 : PubMed