NBD-HE-HP
ABPP-Probe labels many serine hydrolases and not only alpha/beta hydrolases . Compound XXX1 in Oskolkova_2003_Chem.Phys.Lipids_125_103
General
Type : Organophosphate,ABPP-Probe,NBD-nitro-benzoxadiazol-fluorescent,pNP,Benzoxadiazole
Chemical_Nomenclature : N-[2-[hexyl-(4-nitrophenoxy)phosphoryl]oxyethyl]-6-[(4-nitro-2,1,3-benzoxadiazol-7-yl)amino]hexanamide
Canonical SMILES : CCCCCCP(=O)(OCCNC(=O)CCCCCNC1=CC=C(C2=NON=C12)[N+](=O)[O-])OC3=CC=C(C=C3)[N+](=O)[O-]
InChI : InChI=1S\/C26H35N6O9P\/c1-2-3-4-8-19-42(38,40-21-12-10-20(11-13-21)31(34)35)39-18-17-28-24(33)9-6-5-7-16-27-22-14-15-23(32(36)37)26-25(22)29-41-30-26\/h10-15,27H,2-9,16-19H2,1H3,(H,28,33)
InChIKey : ZFHHVTNYROZCIO-UHFFFAOYSA-N
Other name(s) : AC1LD8L8,SCHEMBL13199489,LP106166,2-{6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexaneamido}ethyl 4-nitrophenyl hexylphosphonate,689264-29-7,N-[2-[hexyl-(4-nitrophenoxy)phosphoryl]oxyethyl]-6-[(4-nitro-2,1,3-benzoxadiazol-7-yl)amino]hexanamide,(O-((6-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)hexanoyl)aminoethyl-O-(n-hexyl)phosphonic acid p-nitrophenyl ester
MW : 606.56
Formula : C26H35N6O9P
CAS_number :
PubChem : 644117
UniChem : ZFHHVTNYROZCIO-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
Families : NBD-HE-HP ligand of proteins in family: Hormone-sensitive_lipase_like || Carb_B_Chordata || Monoglyceridelipase_lysophospholip || A85-EsteraseD-FGH || ABHD11-Acetyl_transferase || LYsophospholipase_carboxylesterase || PPase_methylesterase_euk || ACPH_Peptidase_S9 || CGI-58_ABHD5_ABHD4 || Bacterial_lip_FamI.2 || Lipase_3 || Carb_B_Arthropoda || Juvenile_hormone_esterase || S9N_PPCE_Peptidase_S9
Stucture :
References (5)
| Title : Functional fat body proteomics and gene targeting reveal in vivo functions of Drosophila melanogaster a-Esterase-7 - Birner-Gruenberger_2012_Insect.Biochem.Mol.Biol_42_220 |
| Author(s) : Birner-Gruenberger R , Bickmeyer I , Lange J , Hehlert P , Hermetter A , Kollroser M , Rechberger GN , Kuhnlein RP |
| Ref : Insect Biochemistry & Molecular Biology , 42 :220 , 2012 |
| Abstract : Birner-Gruenberger_2012_Insect.Biochem.Mol.Biol_42_220 |
| ESTHER : Birner-Gruenberger_2012_Insect.Biochem.Mol.Biol_42_220 |
| PubMedSearch : Birner-Gruenberger_2012_Insect.Biochem.Mol.Biol_42_220 |
| PubMedID: 22198472 |
| Gene_locus related to this paper: drome-aes02 , drome-aes05 , drome-CG1882 , drome-CG2059 , drome-CG5355 , drome-CG8425 , drome-CG18815 , drome-EST23aes07 , drome-este6 |
| Title : Functional proteomic analysis of lipases and esterases in cultured human adipocytes - Schicher_2010_J.Proteome.Res_9_6334 |
| Author(s) : Schicher M , Morak M , Birner-Gruenberger R , Kayer H , Stojcic B , Rechberger G , Kollroser M , Hermetter A |
| Ref : J Proteome Res , 9 :6334 , 2010 |
| Abstract : Schicher_2010_J.Proteome.Res_9_6334 |
| ESTHER : Schicher_2010_J.Proteome.Res_9_6334 |
| PubMedSearch : Schicher_2010_J.Proteome.Res_9_6334 |
| PubMedID: 20942458 |
| Title : Novel fluorescent phosphonic acid esters for discrimination of lipases and esterases - Schmidinger_2005_Chembiochem_6_1776 |
| Author(s) : Schmidinger H , Birner-Gruenberger R , Riesenhuber G , Saf R , Susani-Etzerodt H , Hermetter A |
| Ref : Chembiochem , 6 :1776 , 2005 |
| Abstract : Schmidinger_2005_Chembiochem_6_1776 |
| ESTHER : Schmidinger_2005_Chembiochem_6_1776 |
| PubMedSearch : Schmidinger_2005_Chembiochem_6_1776 |
| PubMedID: 16094692 |
| Title : The lipolytic proteome of mouse adipose tissue - Birner-Gruenberger_2005_Mol.Cell.Proteomics_4_1710 |
| Author(s) : Birner-Gruenberger R , Susani-Etzerodt H , Waldhuber M , Riesenhuber G , Schmidinger H , Rechberger G , Kollroser M , Strauss JG , Lass A , Zimmermann R , Haemmerle G , Zechner R , Hermetter A |
| Ref : Mol Cell Proteomics , 4 :1710 , 2005 |
| Abstract : Birner-Gruenberger_2005_Mol.Cell.Proteomics_4_1710 |
| ESTHER : Birner-Gruenberger_2005_Mol.Cell.Proteomics_4_1710 |
| PubMedSearch : Birner-Gruenberger_2005_Mol.Cell.Proteomics_4_1710 |
| PubMedID: 16048907 |
| Title : Fluorescent organophosphonates as inhibitors of microbial lipases - Oskolkova_2003_Chem.Phys.Lipids_125_103 |
| Author(s) : Oskolkova OV , Saf R , Zenzmaier E , Hermetter A |
| Ref : Chemistry & Physic of Lipids , 125 :103 , 2003 |
| Abstract : Oskolkova_2003_Chem.Phys.Lipids_125_103 |
| ESTHER : Oskolkova_2003_Chem.Phys.Lipids_125_103 |
| PubMedSearch : Oskolkova_2003_Chem.Phys.Lipids_125_103 |
| PubMedID: 14499469 |