PSK

General

Type : Organophosphate

Chemical_Nomenclature : [(3R,4S)-4-hydroxy-3-methyl-2-oxohexyl]phosphinic acid

Canonical SMILES : CCC(C(C)C(=O)CP(=O)O)O

InChI : InChI=1S\/C7H15O4P\/c1-3-6(8)5(2)7(9)4-12(10)11\/h5-6,8,12H,3-4H2,1-2H3,(H,10,11)\/t5-,6+\/m1\/s1

InChIKey : UXHVQAJQXZWLAW-RITPCOANSA-N

Other name(s) : PSK,DB08431


MW : 194.16

Formula : C7H15O4P

CAS_number :

PubChem : 46937177

UniChem : UXHVQAJQXZWLAW-RITPCOANSA-N

IUPHAR :

Wikipedia :

Target

Families : PSK ligand of proteins in family: Thioesterase

Stucture : 2H7Y Pikromycin Thioesterase with covalent affinity label

Protein : strve-PIKAIV

References (1)

Title : Structural and mechanistic insights into polyketide macrolactonization from polyketide-based affinity labels - Giraldes_2006_Nat.Chem.Biol_2_531
Author(s) : Giraldes JW , Akey DL , Kittendorf JD , Sherman DH , Smith JL , Fecik RA
Ref : Nat Chemical Biology , 2 :531 , 2006
Abstract : Giraldes_2006_Nat.Chem.Biol_2_531
ESTHER : Giraldes_2006_Nat.Chem.Biol_2_531
PubMedSearch : Giraldes_2006_Nat.Chem.Biol_2_531
PubMedID: 16969373
Gene_locus related to this paper: strve-PIKAIV