RG6
General
Type : Strigolactone receptors ligand
Chemical_Nomenclature : 2-[1-[(4-ethoxyphenyl)methyl]-4-[3-(4-methoxyphenyl)prop-2-enyl]piperazin-2-yl]ethanol
Canonical SMILES : CCOC1=CC=C(C=C1)CN2CCN(CC2CCO)CC=CC3=CC=C(C=C3)OC
InChI : InChI=1S\/C25H34N2O3\/c1-3-30-25-12-8-22(9-13-25)19-27-17-16-26(20-23(27)14-18-28)15-4-5-21-6-10-24(29-2)11-7-21\/h4-13,23,28H,3,14-20H2,1-2H3\/b5-4+\/t23-\/m0\/s1
InChIKey : MBXADFLSFSJJOZ-UHFFFAOYSA-N || MBXADFLSFSJJOZ-OIUIXCLQSA-N
Other name(s) : MCULE-8511489798,HFJ,2-{(2S)-1-[(4-ethoxyphenyl)methyl]-4-[(2E)-3-(4-methoxyphenyl)prop-2-en-1-yl]piperazin-2-yl}ethan-1-ol,2-[1-[(4-ethoxyphenyl)methyl]-4-[(~{E})-3-(4-methoxyphenyl)prop-2-enyl]piperazin-2-yl]ethanol,ZINC22913448
MW : 410.5
Formula : C25H34N2O3
CAS_number :
UniChem : MBXADFLSFSJJOZ-UHFFFAOYSA-N || MBXADFLSFSJJOZ-OIUIXCLQSA-N
IUPHAR :
Wikipedia :
Target
Families : RG6 ligand of proteins in family: RsbQ-like
Stucture : 7SNU Crystal structure of ShHTL7 from Striga hermonthica in complex with strigolactone antagonist RG6
Protein : strhe-ShHTL7
References (2)
| Title : A novel strigolactone receptor antagonist provides insights into the structural inhibition, conditioning, and germination of the crop parasite Striga - Arellano-Saab_2022_J.Biol.Chem_298_101734 |
| Author(s) : Arellano-Saab A , McErlean CSP , Lumba S , Savchenko A , Stogios PJ , McCourt P |
| Ref : Journal of Biological Chemistry , :101734 , 2022 |
| Abstract : Arellano-Saab_2022_J.Biol.Chem_298_101734 |
| ESTHER : Arellano-Saab_2022_J.Biol.Chem_298_101734 |
| PubMedSearch : Arellano-Saab_2022_J.Biol.Chem_298_101734 |
| PubMedID: 35181340 |
| Gene_locus related to this paper: strhe-ShHTL7 |
| Title : Small-molecule antagonists of germination of the parasitic plant Striga hermonthica - Holbrook-Smith_2016_Nat.Chem.Biol_12_724 |
| Author(s) : Holbrook-Smith D , Toh S , Tsuchiya Y , McCourt P |
| Ref : Nat Chemical Biology , 12 :724 , 2016 |
| Abstract : Holbrook-Smith_2016_Nat.Chem.Biol_12_724 |
| ESTHER : Holbrook-Smith_2016_Nat.Chem.Biol_12_724 |
| PubMedSearch : Holbrook-Smith_2016_Nat.Chem.Biol_12_724 |
| PubMedID: 27428512 |