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Inhibitor Report for: TAM5

General
Type Benzofuran, Morpholine
Chemical_Nomenclature ethyl 5-hydroxy-4-(morpholin-4-ylmethyl)-2-phenyl-1-benzofuran-3-carboxylate
Canonical SMILES CCOC(=O)C1=C(OC2=C1C(=C(C=C2)O)CN3CCOCC3)C4=CC=CC=C4
InChI InChI=1S/C22H23NO5/c1-2-27-22(25)20-19-16(14-23-10-12-26-13-11-23)17(24)8-9-18(19)28-21(20)15-6-4-3-5-7-15/h3-9,24H,2,10-14H2,1H3
InChIKey OGXGATRCXHSTEV-UHFFFAOYSA-N
Other name(s) MLS000061958 ; SMR000070819 ; Ethyl 5-hydroxy-4-(4-morpholinylmethyl)-2-phenyl-1-benzofuran-3-carboxylate ; 80592-84-3 ; BAS 01057783
________________________________________________________________________________________________
MW|381.42
Formula|C22H23NO5
CAS_number|
PubChem|1113703
UniChem|OGXGATRCXHSTEV-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | TAM5 ligand of proteins in family: Thioesterase
Stucture | 1 structure: 5V41: Crystal Structure of Mtb Pks13 Thioesterase domain in complex with inhibitor TAM5
Protein | myctu-PKS13

References:
Search PubMed for references concerning: TAM5
    Title: Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13
    Aggarwal A, Parai MK, Shetty N, Wallis D, Woolhiser L, Hastings C, Dutta NK, Galaviz S, Dhakal RC and Sacchettini JC <20 more author(s)>
    Ref: Cell, 170:249, 2017 : PubMed