Tolfenamic-acid

General

Type : Benzoate

Chemical_Nomenclature : 2-(3-chloro-2-methylanilino)benzoic acid

Canonical SMILES : CC1=C(C=CC=C1Cl)NC2=CC=CC=C2C(=O)O

InChI : InChI=1S\/C14H12ClNO2\/c1-9-11(15)6-4-8-12(9)16-13-7-3-2-5-10(13)14(17)18\/h2-8,16H,1H3,(H,17,18)

InChIKey : YEZNLOUZAIOMLT-UHFFFAOYSA-N

Other name(s) : Tolfenamic acid,Clotam,N-(3-Chloro-2-methylphenyl)anthranilic acid,2-[(3-Chloro-2-methylphenyl)amino]benzoic Acid,Tolfedine


MW : 261.70

Formula : C14H12ClNO2

CAS_number : 13710-19-5

PubChem : 610479

UniChem : YEZNLOUZAIOMLT-UHFFFAOYSA-N

IUPHAR :

Wikipedia :

Target

Families : Tolfenamic-acid ligand of proteins in family: RsbQ-like

Stucture : 6AP6 Crystal Structure of DAD2 in complex with tolfenamic acid

Protein : orysj-Q10QA5

References (1)

Title : Inhibition of strigolactone receptors by N-phenylanthranilic acid derivatives: Structural and functional insights - Hamiaux_2018_J.Biol.Chem_293_6530
Author(s) : Hamiaux C , Drummond RSM , Luo Z , Lee HW , Sharma P , Janssen BJ , Perry NB , Denny WA , Snowden KC
Ref : Journal of Biological Chemistry , 293 :6530 , 2018
Abstract : Hamiaux_2018_J.Biol.Chem_293_6530
ESTHER : Hamiaux_2018_J.Biol.Chem_293_6530
PubMedSearch : Hamiaux_2018_J.Biol.Chem_293_6530
PubMedID: 29523686
Gene_locus related to this paper: pethy-dad2