DPPIV peptidase activity is inhibited by N-terminal nonapeptide Tat-(1-9) of Tat protein from human immunodeficiency virus (HIV)-1 with amino acid sequence here a mutant with Trp2 MWPVDPNIE
Type : Peptide,Sulfur Compound
Chemical_Nomenclature : MWPVDPNIE
Canonical SMILES : CC.CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)O)NC(=O)C(CC(=O)N)NC(=O)C1CCCN1C(=O)C(CC(=O)O)NC(=O)C(C(C)C)NC(=O)C2CCCN2C(=O)C(CC3=CNC4C3CCC=C4)NC(=O)C(CCSC)N
InChI :
InChIKey :
Other name(s) : H-Met-Trp-Pro-Val-Asp-Pro-Asn-Ile-Glu-OH,MWPVDPNIE,HIV-1 Trp2 Tat(1-9),HIV-1 Trp2 tat Protein (1-9)
MW : 1104.28
Formula : C50H77N11O15S
CAS_number :
PubChem :
UniChem :
IUPHAR :
Wikipedia :
Families : Trp2-Tat-(1-9) ligand of proteins in family: DPP4N_Peptidase_S9
Stucture : 2BGN HIV-1 Tat protein derived N-terminal nonapeptide Trp2-Tat(1-9) bound to the active site of Dipeptidyl peptidase IV (CD26)
Protein : human-DPP4
Title : Crystal structures of HIV-1 Tat-derived nonapeptides Tat-(1-9) and Trp2-Tat-(1-9) bound to the active site of dipeptidyl-peptidase IV (CD26) - Weihofen_2005_J.Biol.Chem_280_14911 |
Author(s) : Weihofen WA , Liu J , Reutter W , Saenger W , Fan H |
Ref : Journal of Biological Chemistry , 280 :14911 , 2005 |
Abstract : Weihofen_2005_J.Biol.Chem_280_14911 |
ESTHER : Weihofen_2005_J.Biol.Chem_280_14911 |
PubMedSearch : Weihofen_2005_J.Biol.Chem_280_14911 |
PubMedID: 15695814 |
Gene_locus related to this paper: human-DPP4 |