Tyrosinamide
General
Type : Product-like inhibitor
Chemical_Nomenclature : [(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]azanium
Canonical SMILES : C1=CC(=CC=C1CC(C(=O)N)[NH3+])O
InChI : InChI=1S\/C9H12N2O2\/c10-8(9(11)13)5-6-1-3-7(12)4-2-6\/h1-4,8,12H,5,10H2,(H2,11,13)\/p+1\/t8-\/m0\/s1
InChIKey : PQFMNVGMJJMLAE-QMMMGPOBSA-O
Other name(s) : TYC,AC1OLQW2,[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]azanium
MW : 181.21
Formula : C9H13N2O2+
CAS_number :
PubChem : 7408188
UniChem : PQFMNVGMJJMLAE-QMMMGPOBSA-O
IUPHAR :
Wikipedia :
Target
Families : Tyrosinamide ligand of proteins in family: Valacyclovir-hydrolase
Stucture : 2OCI Crystal structure of valacyclovir hydrolase complexed with a product analogue
Protein : human-BPHL
References (1)
| Title : Molecular basis of prodrug activation by human valacyclovirase, an alpha-amino acid ester hydrolase - Lai_2008_J.Biol.Chem_283_9318 |
| Author(s) : Lai L , Xu Z , Zhou J , Lee KD , Amidon GL |
| Ref : Journal of Biological Chemistry , 283 :9318 , 2008 |
| Abstract : Lai_2008_J.Biol.Chem_283_9318 |
| ESTHER : Lai_2008_J.Biol.Chem_283_9318 |
| PubMedSearch : Lai_2008_J.Biol.Chem_283_9318 |
| PubMedID: 18256025 |
| Gene_locus related to this paper: human-BPHL |