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Inhibitor Report for: UB-EV-52

General
Type Adamantyl, Urea derivative
Chemical_Nomenclature 4-[4-(2-oxatricyclo[3.3.1.13,7]decan-1-ylcarbamoylamino)cyclohexyl]oxybenzoic acid
Canonical SMILES C1CC(CCC1NC(=O)NC23CC4CC(C2)CC(C4)O3)OC5=CC=C(C=C5)C(=O)O
InChI InChI=1S/C23H30N2O5/c26-21(27)16-1-5-18(6-2-16)29-19-7-3-17(4-8-19)24-22(28)25-23-12-14-9-15(13-23)11-20(10-14)30-23/h1-2,5-6,14-15,17,19-20H,3-4,7-13H2,(H,26,27)(H2,24,25,28)
InChIKey TUSNDHHKQPKMJV-UHFFFAOYSA-N
Other name(s) SCHEMBL18424948 ; SCHEMBL18424949
________________________________________________________________________________________________
MW|414.5
Formula|C23H30N2O5
CAS_number|
PubChem|126508342
UniChem|TUSNDHHKQPKMJV-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | UB-EV-52 ligand of proteins in family: Epoxide_hydrolase
Protein | human-EPHX2

References:
Search PubMed for references concerning: UB-EV-52
    Title: Inhibition of Soluble Epoxide Hydrolase Ameliorates Phenotype and Cognitive Abilities in a Murine Model of Niemann Pick Type C Disease
    Grinan-Ferre C, Companys-Alemany J, Jarne-Ferrer J, Codony S, Gonzalez-Castillo C, Ortuno-Sahagun D, Vilageliu L, Grinberg D, Vazquez S, Pallas M
    Ref: Int J Mol Sci, 22:, 2021 : PubMed

            

    Title: Pharmacological Inhibition of Soluble Epoxide Hydrolase as a New Therapy for Alzheimer's Disease
    Grinan-Ferre C, Codony S, Pujol E, Yang J, Leiva R, Escolano C, Puigoriol-Illamola D, Companys-Alemany J, Corpas R and Galdeano C <8 more author(s)>
    Ref: Neurotherapeutics, :, 2020 : PubMed