Gene Locus : human-BCHE
Mode of mutation : Site directed mutagenesis
Disease :
Summary : Peripheral Anionic Site A277 plays no role in catalytic activity Masson_1995_5th.ChE.Meeting.Madras__230 Masson_1996_Eur.J.Biochem_235_36
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : Peripheral Anionic Site
Torpedo_number : 279
Kinetic Parameter : No kinetic parameter
News : No news
Comment : p.A277W Ala277Trp (p.A305W Ala305Trp in primary sequence with 28 amino-acids signal peptide) A277 plays no role in catalytic activity
| Title : Importance of aspartate-70 in organophosphate inhibition, oxime re-activation and aging of human butyrylcholinesterase - Masson_1997_Biochem.J_325_53 |
| Author(s) : Masson P , Froment MT , Bartels CF , Lockridge O |
| Ref : Biochemical Journal , 325 :53 , 1997 |
| Abstract : Masson_1997_Biochem.J_325_53 |
| ESTHER : Masson_1997_Biochem.J_325_53 |
| PubMedSearch : Masson_1997_Biochem.J_325_53 |
| PubMedID: 9224629 |
| Title : Asp7O in the peripheral anionic site of human butyrylcholinesterase - Masson_1996_Eur.J.Biochem_235_36 |
| Author(s) : Masson P , Froment MT , Bartels CF , Lockridge O |
| Ref : European Journal of Biochemistry , 235 :36 , 1996 |
| Abstract : Masson_1996_Eur.J.Biochem_235_36 |
| ESTHER : Masson_1996_Eur.J.Biochem_235_36 |
| PubMedSearch : Masson_1996_Eur.J.Biochem_235_36 |
| PubMedID: 8631355 |
| Title : Peripheral Anionic Site of Wild-Type and Mutant Human Butyrylcholinesterase - |
| Author(s) : Masson P , Froment MT , Bartels CF , Lockridge O |
| Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :230 , 1995 |
| PubMedID: |