B5-174-A175-487-B488-575_mouse-chimerae-ACHE-BCHE

General

Gene Locus : mouse-BCHE, mouse-ACHE

Mode of mutation : Site directed mutagenesis

Disease :

Summary : Peripheral Anionic Site diff AChE\/BChE BW284C51 specificity affected by first 174 aa(Y72Y124),ethopropazine and iso OMPA by middle part F295F297Y337 Vellom_1993_Biochemistry_32_12 Radic_1993_Biochemistry_32_12074

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : Peripheral Anionic Site

Torpedo_number : Chimerae

Kinetic Parameter : Acetylthiocholine_B5-174-A175-487-B488-575_mouse-chimerae-ACHE-BCHE

News : No news

Comment :

References (2)

Title : Three distinct domains in the cholinesterase molecule confer selectivity for acetyl- and butyrylcholinesterase inhibitors - Radic_1993_Biochemistry_32_12074
Author(s) : Radic Z , Pickering NA , Vellom DC , Camp S , Taylor P
Ref : Biochemistry , 32 :12074 , 1993
Abstract : Radic_1993_Biochemistry_32_12074
ESTHER : Radic_1993_Biochemistry_32_12074
PubMedSearch : Radic_1993_Biochemistry_32_12074
PubMedID: 8218285

Title : Amino acid residues controlling acetylcholinesterase and butyrylcholinesterase specificity - Vellom_1993_Biochemistry_32_12
Author(s) : Vellom DC , Radic Z , Li Y , Pickering NA , Camp S , Taylor P
Ref : Biochemistry , 32 :12 , 1993
Abstract : Vellom_1993_Biochemistry_32_12
ESTHER : Vellom_1993_Biochemistry_32_12
PubMedSearch : Vellom_1993_Biochemistry_32_12
PubMedID: 8418833