Gene Locus : mouse-BCHE, mouse-ACHE
Mode of mutation : Site directed mutagenesis
Disease :
Summary : Peripheral Anionic Site diff AChE\/BChE BW284C51 specificity affected by first 174 aa(Y72Y124),ethopropazine and iso OMPA by middle part F295F297Y337 Vellom_1993_Biochemistry_32_12 Radic_1993_Biochemistry_32_12074
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : Peripheral Anionic Site
Torpedo_number : Chimerae
Kinetic Parameter : Acetylthiocholine_B5-174-A175-575_mouse-chimerae-ACHE-BCHE, WT-fasciculin2_B5-174-A175-575_mouse-chimerae-ACHE-BCHE
News : No news
Comment :
Title : Three distinct domains in the cholinesterase molecule confer selectivity for acetyl- and butyrylcholinesterase inhibitors - Radic_1993_Biochemistry_32_12074 |
Author(s) : Radic Z , Pickering NA , Vellom DC , Camp S , Taylor P |
Ref : Biochemistry , 32 :12074 , 1993 |
Abstract : Radic_1993_Biochemistry_32_12074 |
ESTHER : Radic_1993_Biochemistry_32_12074 |
PubMedSearch : Radic_1993_Biochemistry_32_12074 |
PubMedID: 8218285 |
Title : Amino acid residues controlling acetylcholinesterase and butyrylcholinesterase specificity - Vellom_1993_Biochemistry_32_12 |
Author(s) : Vellom DC , Radic Z , Li Y , Pickering NA , Camp S , Taylor P |
Ref : Biochemistry , 32 :12 , 1993 |
Abstract : Vellom_1993_Biochemistry_32_12 |
ESTHER : Vellom_1993_Biochemistry_32_12 |
PubMedSearch : Vellom_1993_Biochemistry_32_12 |
PubMedID: 8418833 |