Gene Locus : human-BCHE
Mode of mutation : Site directed mutagenesis
Disease :
Summary : Succinylthiocholine binding Higher Km lower kcat Masson_1997_Biochemistry_36_2266
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : Succinylthiocholine binding
Torpedo_number : 72
Kinetic Parameter : No kinetic parameter
News : No news
Comment : p.D70N Asp70Asn (p.D98N Asp98Asn in primary sequence with 28 amino-acids signal peptide) Higher Km lower kcat
Title : Role of aspartate 70 and tryptophan 82 in binding of succinyldithiocholine to human butyrylcholinesterase - Masson_1997_Biochemistry_36_2266 |
Author(s) : Masson P , Legrand P , Bartels CF , Froment MT , Schopfer LM , Lockridge O |
Ref : Biochemistry , 36 :2266 , 1997 |
Abstract : Masson_1997_Biochemistry_36_2266 |
ESTHER : Masson_1997_Biochemistry_36_2266 |
PubMedSearch : Masson_1997_Biochemistry_36_2266 |
PubMedID: 9047329 |