E432X_human-BCHE

General

Gene Locus : human-BCHE

Mode of mutation : Natural mutant

Disease :

Summary : Natural mutation Levano_2005_Anesthesiology_102_531

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity : Defect in Suxamethonium hydrolysis

Modification : Natural mutation

Torpedo_number : 434

Kinetic Parameter : No kinetic parameter

News : MAY-03-2005

Comment : p.E432X Glu432Ter nucleotide change c.1294G>T (p.E460X Glu460Ter in primary sequence with 28 amino-acids signal peptide) prolonged neuromuscular block after succinylcholine

References (1)

Title : Genotyping the butyrylcholinesterase in patients with prolonged neuromuscular block after succinylcholine - Levano_2005_Anesthesiology_102_531
Author(s) : Levano S , Ginz H , Siegemund M , Filipovic M , Voronkov E , Urwyler A , Girard T
Ref : Anesthesiology , 102 :531 , 2005
Abstract : Levano_2005_Anesthesiology_102_531
ESTHER : Levano_2005_Anesthesiology_102_531
PubMedSearch : Levano_2005_Anesthesiology_102_531
PubMedID: 15731589