Gene Locus : brafl-ACHE2
Mode of mutation : Site directed mutagenesis
Disease :
Summary : Acyl specificity\;Increase in kcat for BsCh\;Pezzementi_2003_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_136_813
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : Acyl specificity
Torpedo_number : 290
Kinetic Parameter : No kinetic parameter
News : APRIL-07-2006, DECEMBER-16-2003
Comment : p.Phe312Ile
| Title : Thermal denaturation of wild type and mutant recombinant acetylcholinesterase from amphioxus: effects of the temperature of in vitro expression and of reversible inhibitors - Perrin_2008_Invert.Neurosci_8_147 |
| Author(s) : Perrin B , Rowland M , Wolfe M , Tsigelny I , Pezzementi L |
| Ref : Invert Neurosci , 8 :147 , 2008 |
| Abstract : Perrin_2008_Invert.Neurosci_8_147 |
| ESTHER : Perrin_2008_Invert.Neurosci_8_147 |
| PubMedSearch : Perrin_2008_Invert.Neurosci_8_147 |
| PubMedID: 18677525 |
| Title : Inactivation of an invertebrate acetylcholinesterase by sulfhydryl reagents: the roles of two cysteines in the catalytic gorge of the enzyme - Pezzementi_2006_Invert.Neurosci_6_47 |
| Author(s) : Pezzementi L , Rowland M , Wolfe M , Tsigelny I |
| Ref : Invert Neurosci , 6 :47 , 2006 |
| Abstract : Pezzementi_2006_Invert.Neurosci_6_47 |
| ESTHER : Pezzementi_2006_Invert.Neurosci_6_47 |
| PubMedSearch : Pezzementi_2006_Invert.Neurosci_6_47 |
| PubMedID: 16586114 |
| Title : Amino acids defining the acyl pocket of an invertebrate cholinesterase - Pezzementi_2003_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_136_813 |
| Author(s) : Pezzementi L , Johnson K , Tsigelny I , Cotney J , Manning E , Barker A , Merritt S |
| Ref : Comparative Biochemistry & Physiology B Biochem Mol Biol , 136 :813 , 2003 |
| Abstract : Pezzementi_2003_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_136_813 |
| ESTHER : Pezzementi_2003_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_136_813 |
| PubMedSearch : Pezzementi_2003_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_136_813 |
| PubMedID: 14662305 |