G119S_tetur-ACHE

General

Gene Locus : tetur-ACHE

Mode of mutation : Natural mutant

Disease :

Summary : OP-resistance\;Insecticide resistance\;Kwon_2010_Pestic.Biochem.Physiol_96_36 || OP-resistance\;Insecticide resistance, amplified allele\;Kwon_2010_Insect.Mol.Biol_19_195 || OP-resistance\;Insecticide resistance, amplified allele\;Kwon_2012_Insect.Biochem.Mol.Biol_42_212

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : OP-resistance

Torpedo_number : 119

Kinetic Parameter : No kinetic parameter

News : No news

Comment : Anasawa et al. the strain TKD is the suceptible strain and the NCN is the resistant strain. Anasawa had found S in the TKD strain so it was probably already resistant see discussion in Kwon et al. || AChE gene duplication results in the proportional overexpression which is necessary for the reduced catalytic activity caused by mutations || p.Gly119Ser G119S G228S

References (7)

Title : Multiple TaqMan qPCR and droplet digital PCR (ddPCR) diagnostics for pesticide resistance monitoring and management, in the major agricultural pest Tetranychus urticae - Mavridis_2022_Pest.Manag.Sci_78_263
Author(s) : Mavridis K , Papapostolou KM , Riga M , Ilias A , Michaelidou K , Bass C , Van Leeuwen T , Tsagkarakou A , Vontas J
Ref : Pest Manag Sci , 78 :263 , 2022
Abstract : Mavridis_2022_Pest.Manag.Sci_78_263
ESTHER : Mavridis_2022_Pest.Manag.Sci_78_263
PubMedSearch : Mavridis_2022_Pest.Manag.Sci_78_263
PubMedID: 34480408

Title : Identification and characterization of striking multiple-insecticide resistance in a Tetranychus urticae field population from Greece - Papapostolou_2021_Pest.Manag.Sci_77_666
Author(s) : Papapostolou KM , Riga M , Charamis J , Skoufa E , Souchlas V , Ilias A , Dermauw W , Ioannidis P , Van Leeuwen T , Vontas J
Ref : Pest Manag Sci , 77 :666 , 2021
Abstract : Papapostolou_2021_Pest.Manag.Sci_77_666
ESTHER : Papapostolou_2021_Pest.Manag.Sci_77_666
PubMedSearch : Papapostolou_2021_Pest.Manag.Sci_77_666
PubMedID: 33051974
Gene_locus related to this paper: tetur-ACHE

Title : Global distribution and origin of target site insecticide resistance mutations in Tetranychus urticae - Ilias_2014_Insect.Biochem.Mol.Biol_48_17
Author(s) : Ilias A , Vontas J , Tsagkarakou A
Ref : Insect Biochemistry & Molecular Biology , 48 :17 , 2014
Abstract : Ilias_2014_Insect.Biochem.Mol.Biol_48_17
ESTHER : Ilias_2014_Insect.Biochem.Mol.Biol_48_17
PubMedSearch : Ilias_2014_Insect.Biochem.Mol.Biol_48_17
PubMedID: 24602758
Gene_locus related to this paper: tetur-ACHE

Title : The overexpression of acetylcholinesterase compensates for the reduced catalytic activity caused by resistance-conferring mutations in Tetranychus urticae - Kwon_2012_Insect.Biochem.Mol.Biol_42_212
Author(s) : Kwon DH , Choi JY , Je YH , Lee SH
Ref : Insect Biochemistry & Molecular Biology , 42 :212 , 2012
Abstract : Kwon_2012_Insect.Biochem.Mol.Biol_42_212
ESTHER : Kwon_2012_Insect.Biochem.Mol.Biol_42_212
PubMedSearch : Kwon_2012_Insect.Biochem.Mol.Biol_42_212
PubMedID: 22198354
Gene_locus related to this paper: tetur-ACHE

Title : Acetylcholinesterase point mutations putatively associated with monocrotophos resistance in the two-spotted spider mite - Kwon_2010_Pestic.Biochem.Physiol_96_36
Author(s) : Kwon DH , Im JS , Ahn JJ , Lee J-H , Clark JM , Lee SH
Ref : Pesticide Biochemistry and Physiology , 96 :36 , 2010
Abstract : Kwon_2010_Pestic.Biochem.Physiol_96_36
ESTHER : Kwon_2010_Pestic.Biochem.Physiol_96_36
PubMedSearch : Kwon_2010_Pestic.Biochem.Physiol_96_36
PubMedID:
Gene_locus related to this paper: tetur-ACHE

Title : Extensive gene duplication of acetylcholinesterase associated with organophosphate resistance in the two-spotted spider mite - Kwon_2010_Insect.Mol.Biol_19_195
Author(s) : Kwon DH , Clark JM , Lee SH
Ref : Insect Molecular Biology , 19 :195 , 2010
Abstract : Kwon_2010_Insect.Mol.Biol_19_195
ESTHER : Kwon_2010_Insect.Mol.Biol_19_195
PubMedSearch : Kwon_2010_Insect.Mol.Biol_19_195
PubMedID: 20002213
Gene_locus related to this paper: tetur-ACHE

Title : Sequence of a cDNA encoding acetylcholinesterase from susceptible and resistant two-spotted spider mite, Tetranychus urticae - Anazawa_2003_Insect.Biochem.Mol.Biol_33_509
Author(s) : Anazawa Y , Tomita T , Aiki Y , Kozaki T , Kono Y
Ref : Insect Biochemistry & Molecular Biology , 33 :509 , 2003
Abstract : Anazawa_2003_Insect.Biochem.Mol.Biol_33_509
ESTHER : Anazawa_2003_Insect.Biochem.Mol.Biol_33_509
PubMedSearch : Anazawa_2003_Insect.Biochem.Mol.Biol_33_509
PubMedID: 12706630
Gene_locus related to this paper: tetur-ACHE