M303I_musdo-EST23aes07

General

Gene Locus : musdo-EST23aes07

Mode of mutation : Natural mutant

Disease :

Summary : OP-resistance\;\;Zhang_2018_Sci.Rep_8_224 || OP-resistance\;\;Zhang_2010_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_156_6

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : OP-resistance

Torpedo_number : 287

Kinetic Parameter : No kinetic parameter

News : No news

Comment : p.Met303Ile n.G909A. For S250T W251S M303I L334L W378R S383T majority of female carried the homozygous susceptible allele in susceptible strain while males were primary heterozygous for these alleles. In resistant strains both male and females were homozygous for the mutation. T found also in some suceptible strains Zhang et al. 2010 Claudianos et al. 1999 and M found in Rutgers resistant strain

References (2)

Title : Multiple mutations and overexpression of the MdaE7 carboxylesterase gene associated with male-linked malathion resistance in housefly, Musca domestica (Diptera: Muscidae) - Zhang_2018_Sci.Rep_8_224
Author(s) : Zhang Y , Li J , Ma Z , Shan C , Gao X
Ref : Sci Rep , 8 :224 , 2018
Abstract : Zhang_2018_Sci.Rep_8_224
ESTHER : Zhang_2018_Sci.Rep_8_224
PubMedSearch : Zhang_2018_Sci.Rep_8_224
PubMedID: 29317643
Gene_locus related to this paper: musdo-EST23aes07

Title : Quantitative and qualitative changes of the carboxylesterase associated with beta-cypermethrin resistance in the housefly, Musca domestica (Diptera: Muscidae) - Zhang_2010_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_156_6
Author(s) : Zhang L , Shi J , Shi X , Liang P , Gao J , Gao X
Ref : Comparative Biochemistry & Physiology B Biochem Mol Biol , 156 :6 , 2010
Abstract : Zhang_2010_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_156_6
ESTHER : Zhang_2010_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_156_6
PubMedSearch : Zhang_2010_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_156_6
PubMedID: 20117228
Gene_locus related to this paper: musdo-EST23aes07