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Mutation Report for: N83Q_human-BCHE

N83Q_human-BCHE
Gene_Locus|human-BCHE
Mode of mutation|Site directed mutagenesis
Amino Acid change|N83Q
Torpedo number|85
Summary|
Comment|p.N83Q Asn83Gln (p.N111Q Asn111Gln in primary sequence with 28 amino-acids signal peptide) loss of substrate activation
Kinetic parameters|none


References:
    Title: Effects of mutations of active site residues and amino acids interacting with the Omega loop on substrate activation of butyrylcholinesterase
    Masson P, Xie W, Froment MT, Lockridge O
    Ref: Biochimica & Biophysica Acta, 1544:166, 2001 : PubMed

            




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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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