Gene Locus : human-BCHE
Mode of mutation : Site directed mutagenesis
Disease :
Summary : Catalysis No activity Gnatt_1994_J.Neurochem_62_749 || Catalytic triad No activity Gnatt_1994_J.Neurochem_62_749
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : Catalytic triad || Catalysis
Torpedo_number : 200
Kinetic Parameter : No kinetic parameter
News : No news
Comment : p.S198D Ser198Asp (p.S226D Ser226Asp in primary sequence with 28 amino-acids signal peptide) No activity active site serine
| Title : Site-directed mutagenesis of active site residues reveals plasticity of human butyrylcholinesterase in substrate and inhibitor interactions - Gnatt_1994_J.Neurochem_62_749 |
| Author(s) : Gnatt A , Loewenstein Y , Yaron A , Schwarz M , Soreq H |
| Ref : Journal of Neurochemistry , 62 :749 , 1994 |
| Abstract : Gnatt_1994_J.Neurochem_62_749 |
| ESTHER : Gnatt_1994_J.Neurochem_62_749 |
| PubMedSearch : Gnatt_1994_J.Neurochem_62_749 |
| PubMedID: 8294937 |