Gene Locus : human-ACHE
Mode of mutation : Site directed mutagenesis
Disease :
Summary : Catalysis Conserved serine no activity Shafferman_2005_Chem.Biol.Interact_157-158_123
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : Catalysis
Torpedo_number : 226
Kinetic Parameter : No kinetic parameter
News : No news
Comment : p.S229A Ser229Ala (p.S250A Ser250Ala in primary sequence with 31 amino-acids signal peptide) Catalysis\;Conserved serine no activity. A mutation of this Ser gives a nul mutant in zebrafish
| Title : Functional requirements for the optimal catalytic configuration of the AChE active center - Shafferman_2005_Chem.Biol.Interact_157-158_123 |
| Author(s) : Shafferman A , Barak D , Kaplan D , Ordentlich A , Kronman C , Velan B |
| Ref : Chemico-Biological Interactions , 157-158 :123 , 2005 |
| Abstract : Shafferman_2005_Chem.Biol.Interact_157-158_123 |
| ESTHER : Shafferman_2005_Chem.Biol.Interact_157-158_123 |
| PubMedSearch : Shafferman_2005_Chem.Biol.Interact_157-158_123 |
| PubMedID: 16256968 |